Understanding GroEL and DnaK Stress Response Proteins as Antigens for Bacterial Diseases

Autologous extracellular Hsp70 exerts a dual role in rheumatoid arthritis

(2020) Stefan Tukaj et al.   CELL STRESS & CHAPERONES

Recent advances in understanding catalysis of protein folding by molecular chaperones

(2020) David Balchin et al.   FEBS LETTERS

Could the Heat Shock Proteins 70 Family Members Exacerbate the Immune Response in Multiple Sclerosis? An in Silico Study

(2020) Luigi Chiricosta et al.   Genes

MUC1 is a receptor for the Salmonella SiiE adhesin that enables apical invasion into enterocytes

(2019) Xinyue Li et al.   PLoS Pathogens

Impact of a Heat Shock Protein Impurity on the Immunogenicity of Biotherapeutic Monoclonal Antibodies

(2019) Shraddha S. Rane et al.   PHARMACEUTICAL RESEARCH

Immunoproteomic analysis of Lawsonia intracellularis identifies candidate neutralizing antibody targets for use in subunit vaccine development

(2019) Milan Obradovic et al.   VETERINARY MICROBIOLOGY

Immunoinformatics approaches to explore Helicobacter Pylori proteome (Virulence Factors) to design B and T cell multi-epitope subunit vaccine

(2019) Mazhar Khan et al.   Scientific Reports

Comparison of protective efficacy between two DNA vaccines encoding DnaK and GroEL against fish nocardiosis

(2019) Jianlin Chen et al.   FISH & SHELLFISH IMMUNOLOGY

Pneumococcal DNA-binding proteins released through autolysis induce the production of proinflammatory cytokines via toll-like receptor 4

(2018) Kosuke Nagai et al.   CELLULAR IMMUNOLOGY

Plasminogen-binding proteins as an evasion mechanism of the host's innate immunity in infectious diseases.

(2018) Dolores A. Ayón-Núñez et al.   BIOSCIENCE REPORTS

GroEL, a novel vaccine candidate of piscine Streptococcus agalactiae identified by immunoproteome

(2018) Wei Li et al.   FISH & SHELLFISH IMMUNOLOGY

MoonProt 2.0: an expansion and update of the moonlighting proteins database

(2017) Chang Chen et al.   NUCLEIC ACIDS RESEARCH

Helicobacter pylori Seropositivity and Childhood Neurodevelopment, the Rhea Birth Cohort in Crete, Greece

(2017) Marianna Karachaliou et al.   PAEDIATRIC AND PERINATAL EPIDEMIOLOGY

Clostridium difficile flagellin FliC: Evaluation as adjuvant and use in a mucosal vaccine against Clostridium difficile

(2017) Jean-François Bruxelle et al.   PLoS One

Inactivation of the dnaK gene in Clostridium difficile 630 Δerm yields a temperature-sensitive phenotype and increases biofilm-forming ability

(2017) Shailesh Jain et al.   Scientific Reports

The surface-displayed chaperones GroEL and DnaK of Mycoplasma pneumoniae interact with human plasminogen and components of the extracellular matrix

(2017) Lisa Hagemann et al.   Pathogens and Disease

Plasmin cleaves fibrinogen and the human complement proteins C3b and C5 in the presence of Leptospira interrogans proteins: A new role of LigA and LigB in invasion and complement immune evasion

(2016) Mónica Marcela Castiblanco-Valencia et al.   IMMUNOBIOLOGY

Influence of Escherichia coli chaperone DnaK on protein immunogenicity

(2016) Kirsty D. Ratanji et al.   IMMUNOLOGY

DNA vaccine encoding molecular chaperone GroEL of Edwardsiella tarda confers protective efficacy against edwardsiellosis

(2016) Fuguo Liu et al.   MOLECULAR IMMUNOLOGY

The GroEL–GroES Chaperonin Machine: A Nano-Cage for Protein Folding

(2016) Manajit Hayer-Hartl et al.   TRENDS IN BIOCHEMICAL SCIENCES

Development of recombinant vaccine candidate molecule against Shigella infection

(2016) S.T.S. Chitradevi et al.   VACCINE

Co-administration of rIpaB domain of Shigella with rGroEL of S. Typhi enhances the immune responses and protective efficacy against Shigella infection

(2015) Sekar Tamil Selvi Chitradevi et al.   Cellular & Molecular Immunology

Heat shock protein vaccines against glioblastoma: from bench to bedside

(2015) Leonel Ampie et al.   JOURNAL OF NEURO-ONCOLOGY

Guillain Barré syndrome (GBS): new insights in the molecular mimicry between C. jejuni and human peripheral nerve (HPN) proteins

(2015) Aida Loshaj-Shala et al.   JOURNAL OF NEUROIMMUNOLOGY

Vaccination with recombinant 4×M2e.HSP70c fusion protein as a universal vaccine candidate enhances both humoral and cell-mediated immune responses and decreases viral shedding against experimental challenge of H9N2 influenza in chickens

(2014) Mehran Dabaghian et al.   VETERINARY MICROBIOLOGY

Pilot study of intratumoral injection of recombinant heat shock protein 70 in the treatment of malignant brain tumors in children

(2014) Maxim Shevtsov et al.   OncoTargets and Therapy

Molecular Chaperone Functions in Protein Folding and Proteostasis

(2013) Yujin E. Kim et al.   Annual Review of Biochemistry

Binational outbreak of Guillain–Barré syndrome associated with Campylobacter jejuni infection, Mexico and USA, 2011

(2013) B. R. JACKSON et al.   EPIDEMIOLOGY AND INFECTION

Increased incidence of Campylobacter jejuni-associated Guillain–Barré syndromes in the Greater Paris area

(2013) V. SIVADON-TARDY et al.   EPIDEMIOLOGY AND INFECTION

Helicobacter pylorisecretes the chaperonin GroEL (HSP60), which binds iron

(2013) Marco Antonio González-López et al.   FEBS LETTERS

Increased Levels of IgG Antibodies against Human HSP60 in Patients with Spondyloarthritis

(2013) Astrid Hjelholt et al.   PLoS One

Epitopes of Microbial and Human Heat Shock Protein 60 and Their Recognition in Myalgic Encephalomyelitis

(2013) Amal Elfaitouri et al.   PLoS One

A novel insecticidal GroEL protein from Xenorhabdus nematophila confers insect resistance in tobacco

(2013) Punam Kumari et al.   TRANSGENIC RESEARCH

An insecticidal protein from Xenorhabdus ehlersii stimulates the innate immune response in Galleria mellonella

(2013) HuaiXing Shi et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Human Milk Mucin 1 and Mucin 4 Inhibit Salmonella enterica Serovar Typhimurium Invasion of Human Intestinal Epithelial Cells In Vitro

(2012) Bo Liu et al.   JOURNAL OF NUTRITION

Role of Streptococcus intermedius DnaK chaperone system in stress tolerance and pathogenicity

(2011) Toshifumi Tomoyasu et al.   CELL STRESS & CHAPERONES

CpG DNA as a vaccine adjuvant

(2011) Christian Bode et al.   Expert Review of Vaccines

Enhancement of antibody responses to native G protein-coupled receptors using E. coli GroEL as a molecular adjuvant in DNA immunization

(2011) Akira Fujimoto et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Mechanisms of the Hsp70 chaperone systemThis paper is one of a selection of papers published in this special issue entitled “Canadian Society of Biochemistry, Molecular & Cellular Biology 52nd Annual Meeting — Protein Folding: Principles and Diseases” and has undergone the Journal's usual peer review process.

(2010) Jason C. Young   Biochemistry and Cell Biology

Immunological efficacy of heat shock protein 60 peptide DiaPep277TM therapy in clinical type I diabetes

(2010) V. A. L. Huurman et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Unique Host Iron Utilization Mechanisms of Helicobacter pylori Revealed with Iron-Deficient Chemically Defined Media

(2010) O. Senkovich et al.   INFECTION AND IMMUNITY

Cellular strategies for the assembly of molecular machines

(2010) Ashwin Chari et al.   TRENDS IN BIOCHEMICAL SCIENCES

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

Converging concepts of protein folding in vitro and in vivo

(2009) F Ulrich Hartl et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Th17 cells in human disease

(2008) Laura A. Tesmer et al.   IMMUNOLOGICAL REVIEWS