- Home
- Publications
- Publication Search
- Publication Details
Title
Mitophagy protects β cells from inflammatory damage in diabetes
Authors
Keywords
-
Journal
JCI Insight
Volume 5, Issue 24, Pages -
Publisher
American Society for Clinical Investigation
Online
2020-11-25
DOI
10.1172/jci.insight.141138
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- MitoTimer-based high-content screen identifies two chemically-related benzothiophene derivatives that enhance basal mitophagy
- (2020) Fernanda M. Cerqueira et al. BIOCHEMICAL JOURNAL
- The E3 ubiquitin ligase parkin is dispensable for metabolic homeostasis in murine pancreatic β cells and adipocytes
- (2019) Callie A. S. Corsa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Islet‐Immune Interactions in Type 1 Diabetes: The Nexus of Beta Cell Destruction
- (2019) Leeana Peters et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- The type 1 diabetes candidate gene Dexi does not affect disease risk in the nonobese diabetic mouse model
- (2019) Janice M. Nieves-Bonilla et al. GENES AND IMMUNITY
- Clarifying the function of genes at the chromosome 16p13 locus in type 1 diabetes: CLEC16A and DEXI
- (2019) Morgan A. Gingerich et al. GENES AND IMMUNITY
- The Good and the Bad of Mitochondrial Breakups
- (2019) Hans-Georg Sprenger et al. TRENDS IN CELL BIOLOGY
- A pipeline for multidimensional confocal analysis of mitochondrial morphology, function, and dynamics in pancreatic β-cells
- (2019) Ahsen Chaudhry et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Mitochondrial Reactive Oxygen Species and Type 1 Diabetes
- (2018) Jing Chen et al. ANTIOXIDANTS & REDOX SIGNALING
- A ubiquitin-dependent mitophagy complex maintains mitochondrial function and insulin secretion in beta cells
- (2018) Gemma Pearson et al. Autophagy
- Interleukin-6 Reduces β-Cell Oxidative Stress by Linking Autophagy With the Antioxidant Response
- (2018) Michelle R. Marasco et al. DIABETES
- CLEC16A regulates splenocyte and NK cell function in part through MEK signaling
- (2018) Rahul Pandey et al. PLoS One
- Elamipretide Promotes Mitophagosome Formation and Prevents Its Reduction Induced by Nutrient Excess in INS1 β-cells
- (2018) Anton Petcherski et al. JOURNAL OF MOLECULAR BIOLOGY
- Evolving and Expanding the Roles of Mitophagy as a Homeostatic and Pathogenic Process
- (2018) Åsa B. Gustafsson et al. PHYSIOLOGICAL REVIEWS
- A fluorescence-based imaging method to measure in vitro and in vivo mitophagy using mt-Keima
- (2017) Nuo Sun et al. Nature Protocols
- Inhibition of Miro1 disturbs mitophagy and pancreatic β-cell function interfering insulin release via IRS-Akt-Foxo1 in diabetes
- (2017) Lingling Chen et al. Oncotarget
- T cells display mitochondria hyperpolarization in human type 1 diabetes
- (2017) Jing Chen et al. Scientific Reports
- Phase Analysis of Metabolic Oscillations and Membrane Potential in Pancreatic Islet β -Cells
- (2016) Matthew J. Merrins et al. BIOPHYSICAL JOURNAL
- Lenalidomide Stabilizes the Erythropoietin Receptor by Inhibiting the E3 Ubiquitin Ligase RNF41
- (2016) A. A. Basiorka et al. CANCER RESEARCH
- NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria
- (2016) Zhenyu Zhong et al. CELL
- Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes
- (2016) James Dooley et al. NATURE GENETICS
- Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents
- (2016) Dongryeol Ryu et al. NATURE MEDICINE
- Clec16a is Critical for Autolysosome Function and Purkinje Cell Survival
- (2016) Veronika Redmann et al. Scientific Reports
- Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1
- (2016) Rebecca Rojansky et al. eLife
- Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis
- (2015) Marvin M. van Luijn et al. BRAIN
- Diabetes Susceptibility GenesPdx1andClec16aFunction in a Pathway Regulating Mitophagy in β-Cells
- (2015) Scott A. Soleimanpour et al. DIABETES
- The Autoimmunity-Associated Gene CLEC16A Modulates Thymic Epithelial Cell Autophagy and Alters T Cell Selection
- (2015) Cornelia Schuster et al. IMMUNITY
- MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5
- (2015) Catherine L. Nezich et al. JOURNAL OF CELL BIOLOGY
- MitoLoc: A method for the simultaneous quantification of mitochondrial network morphology and membrane potential in single cells
- (2015) Jakob Vowinckel et al. MITOCHONDRION
- Mitochondrial regulation of β-cell function: Maintaining the momentum for insulin release
- (2015) Brett A. Kaufman et al. MOLECULAR ASPECTS OF MEDICINE
- Measuring In Vivo Mitophagy
- (2015) Nuo Sun et al. MOLECULAR CELL
- The Diabetes Susceptibility Gene Clec16a Regulates Mitophagy
- (2014) Scott A. Soleimanpour et al. CELL
- Ins1 Cre knock-in mice for beta cell-specific gene recombination
- (2014) Bernard Thorens et al. DIABETOLOGIA
- Pentamethinium fluorescent probes: The impact of molecular structure on photophysical properties and subcellular localization
- (2014) T. Bříza et al. DYES AND PIGMENTS
- Nitric Oxide Induces Ataxia Telangiectasia Mutated (ATM) Protein-dependent γH2AX Protein Formation in Pancreatic β Cells
- (2014) Bryndon J. Oleson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Incretin-Modulated Beta Cell Energetics in Intact Islets of Langerhans
- (2014) David J. Hodson et al. MOLECULAR ENDOCRINOLOGY
- The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis
- (2013) Lindsey E. Padgett et al. Annals of the New York Academy of Sciences
- Loss of iron triggers PINK1/Parkin-independent mitophagy
- (2013) George F G Allen et al. EMBO REPORTS
- Islet inflammation: a unifying target for diabetes treatment?
- (2013) Yumi Imai et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Beta Cell Dysfunction and Insulin Resistance
- (2013) Marlon E. Cerf Frontiers in Endocrinology
- Divalent Metal Transporter 1 Regulates Iron-Mediated ROS and Pancreatic β Cell Fate in Response to Cytokines
- (2012) Jakob Bondo Hansen et al. Cell Metabolism
- PINK1- and Parkin-mediated mitophagy at a glance
- (2012) Seok Min Jin et al. JOURNAL OF CELL SCIENCE
- Impaired Mitochondrial Respiratory Functions and Oxidative Stress in Streptozotocin-Induced Diabetic Rats
- (2011) Haider Raza et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Autophagy: cellular and molecular mechanisms
- (2010) Danielle Glick et al. JOURNAL OF PATHOLOGY
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
- (2010) Josée Dupuis et al. NATURE GENETICS
- A genetically encoded fluorescent reporter of ATP:ADP ratio
- (2009) Jim Berg et al. NATURE METHODS
- Dynamics and diversity in autophagy mechanisms: lessons from yeast
- (2009) Hitoshi Nakatogawa et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia
- (2008) Hye Seung Jung et al. Cell Metabolism
- A novel method for the detection of viable human pancreatic beta cells by flow cytometry using fluorophores that selectively detect labile zinc, mitochondrial membrane potential and protein thiols
- (2008) Sundararajan Jayaraman CYTOMETRY PART A
- Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
- (2008) Gilad Twig et al. EMBO JOURNAL
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now