Tissue-resident CD4+ T helper cells assist the development of protective respiratory B and CD8+ T cell memory responses

Long-lived T follicular helper cells retain plasticity and help sustain humoral immunity

(2020) Marco Künzli et al.   Science Immunology

Memory T Cell Dynamics in the Lung during Influenza Virus Infection

(2019) Angela Pizzolla et al.   JOURNAL OF IMMUNOLOGY

Development of a Universal Influenza Vaccine

(2019) Leonardo D. Estrada et al.   JOURNAL OF IMMUNOLOGY

CD4+ resident memory T cells dominate immunosurveillance and orchestrate local recall responses

(2019) Lalit K. Beura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T Follicular Helper Cell Biology: A Decade of Discovery and Diseases

(2019) Shane Crotty   IMMUNITY

Establishment and Maintenance of Conventional and Circulation-Driven Lung-Resident Memory CD8+ T Cells Following Respiratory Virus Infections

(2019) Shiki Takamura et al.   Frontiers in Immunology

PD-1hi CD8+ resident memory T cells balance immunity and fibrotic sequelae

(2019) Zheng Wang et al.   Science Immunology

The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8+ T Cell Fitness and Functionality

(2019) Chaofan Li et al.   IMMUNITY

Inhibition of IL-2 responsiveness by IL-6 is required for the generation of GC-TFH cells

(2019) Amber Papillion et al.   Science Immunology

Kinetics and Phenotype of the CD4 T Cell Response to Influenza Virus Infections

(2019) Emma E. Hornick et al.   Frontiers in Immunology

Tissue-Resident Macrophages Limit Pulmonary CD8 Resident Memory T Cell Establishment

(2019) Nick P. Goplen et al.   Frontiers in Immunology

CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer

(2019) Ryan Zander et al.   IMMUNITY

Cross-Reactivity with Self-Antigen Tunes the Functional Potential of Naive B Cells Specific for Foreign Antigens

(2019) Holly R. Steach et al.   JOURNAL OF IMMUNOLOGY

Transcriptional programming of tissue-resident memory CD8 + T cells

(2018) J Justin Milner et al.   CURRENT OPINION IN IMMUNOLOGY

Understanding Subset Diversity in T Cell Memory

(2018) Stephen C. Jameson et al.   IMMUNITY

Annual estimates of the burden of seasonal influenza in the United States: A tool for strengthening influenza surveillance and preparedness

(2018) Melissa A. Rolfes et al.   Influenza and Other Respiratory Viruses

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory

(2018) Lalit K. Beura et al.   NATURE IMMUNOLOGY

Local proliferation maintains a stable pool of tissue-resident memory T cells after antiviral recall responses

(2018) Simone L. Park et al.   NATURE IMMUNOLOGY

T Cells That Help B Cells in Chronically Inflamed Tissues

(2018) Deepak A. Rao   Frontiers in Immunology

The establishment of resident memory B cells in the lung requires local antigen encounter

(2018) S. Rameeza Allie et al.   NATURE IMMUNOLOGY

Neonatal hyperoxia promotes asthma-like features through IL-33–dependent ILC2 responses

(2017) In Su Cheon et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis

(2017) Deepak A. Rao et al.   NATURE

Is It Possible to Develop a “Universal” Influenza Virus Vaccine?

(2017) Davide Angeletti et al.   Cold Spring Harbor Perspectives in Biology

Precocious Interleukin 21 Expression in Naive Mice Identifies a Natural Helper Cell Population in Autoimmune Disease

(2017) Elisabeth A. Marnik et al.   Cell Reports

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

(2017) Brahma V. Kumar et al.   Cell Reports

Environmental cues orchestrate regional immune surveillance and protection by pulmonary CTLs

(2016) Linda S. Cauley   JOURNAL OF LEUKOCYTE BIOLOGY

Access of protective antiviral antibody to neuronal tissues requires CD4 T-cell help

(2016) Norifumi Iijima et al.   NATURE

IL-21 and T Cell Differentiation: Consider the Context

(2016) Yuan Tian et al.   TRENDS IN IMMUNOLOGY

Local T/B cooperation in inflamed tissues is supported by T follicular helper-like cells

(2016) Dana Vu Van et al.   Nature Communications

Inducible Bronchus-Associated Lymphoid Tissue: Taming Inflammation in the Lung

(2016) Ji Young Hwang et al.   Frontiers in Immunology

Distinct germinal center selection at local sites shapes memory B cell response to viral escape

(2015) Yu Adachi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Airway-Resident Memory CD8 T Cells Provide Antigen-Specific Protection against Respiratory Virus Challenge through Rapid IFN-γ Production

(2015) Sean R. McMaster et al.   JOURNAL OF IMMUNOLOGY

Exit Strategies: S1P Signaling and T Cell Migration

(2015) Audrey Baeyens et al.   TRENDS IN IMMUNOLOGY

A Critical Role of IL-21-Induced BATF in Sustaining CD8-T-Cell-Mediated Chronic Viral Control

(2015) Gang Xin et al.   Cell Reports

TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection

(2015) Tuoqi Wu et al.   Cell Reports

Tissue-Resident Memory T Cells

(2014) Jason M. Schenkel et al.   IMMUNITY

CD4+ T Cell Help Guides Formation of CD103+ Lung-Resident Memory CD8+ T Cells during Influenza Viral Infection

(2014) Brian J. Laidlaw et al.   IMMUNITY

Epitope-Specific Regulation of Memory Programming by Differential Duration of Antigen Presentation to Influenza-Specific CD8+ T Cells

(2014) André Ballesteros-Tato et al.   IMMUNITY

Intravascular staining for discrimination of vascular and tissue leukocytes

(2014) Kristin G Anderson et al.   Nature Protocols

Interferon Regulatory Factor 4 Sustains CD8+ T Cell Expansion and Effector Differentiation

(2013) Shuyu Yao et al.   IMMUNITY

Insights into the Role of Bcl6 in Follicular Th Cells Using a New Conditional Mutant Mouse Model

(2013) K. Hollister et al.   JOURNAL OF IMMUNOLOGY

Highly Pathological Influenza A Virus Infection Is Associated with Augmented Expression of PD-1 by Functionally Compromised Virus-Specific CD8+ T Cells

(2013) J. A. Rutigliano et al.   JOURNAL OF VIROLOGY

Lung niches for the generation and maintenance of tissue-resident memory T cells

(2013) D L Turner et al.   Mucosal Immunology

Role of T cell immunity in recovery from influenza virus infection

(2013) Jie Sun et al.   Current Opinion in Virology

Memory B cells in the lung participate in protective humoral immune responses to pulmonary influenza virus reinfection

(2012) T. Onodera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antiviral CD8+T cell effector activities in situ are regulated by target cell type

(2010) Matthew M. Hufford et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD8+ T lymphocyte mobilization to virus-infected tissue requires CD4+ T-cell help

(2009) Yusuke Nakanishi et al.   NATURE

Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10

(2009) Jie Sun et al.   NATURE MEDICINE

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

Bcl6 Mediates the Development of T Follicular Helper Cells

(2009) R. I. Nurieva et al.   SCIENCE