Tissue-Resident Macrophages Limit Pulmonary CD8 Resident Memory T Cell Establishment

PPAR-γ in macrophages limits pulmonary inflammation and promotes host recovery following respiratory viral infection

(2019) Su Huang et al.   JOURNAL OF VIROLOGY

Targeting Peroxisome Proliferator-Activated Receptor-Gamma Decreases Host Mortality After Influenza Infection in Obese Mice

(2019) Su Huang et al.   VIRAL IMMUNOLOGY

PD-1hi CD8+ resident memory T cells balance immunity and fibrotic sequelae

(2019) Zheng Wang et al.   Science Immunology

KLRG1 + Effector CD8 + T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity

(2018) Dietmar Herndler-Brandstetter et al.   IMMUNITY

Inflammatory monocytes contribute to the persistence of CXCR3hi CX3CR1lo circulating and lung-resident memory CD8+ T cells following respiratory virus infection

(2018) Pritesh Desai et al.   IMMUNOLOGY AND CELL BIOLOGY

PPAR-γ in innate and adaptive lung immunity

(2018) Samuel Philip Nobs et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Pulmonary antigen encounter regulates the establishment of tissue-resident CD8 memory T cells in the lung airways and parenchyma

(2018) Sean R. McMaster et al.   Mucosal Immunology

Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory

(2018) Lalit K. Beura et al.   NATURE IMMUNOLOGY

Local proliferation maintains a stable pool of tissue-resident memory T cells after antiviral recall responses

(2018) Simone L. Park et al.   NATURE IMMUNOLOGY

Niches for the Long-Term Maintenance of Tissue-Resident Memory T Cells

(2018) Shiki Takamura   Frontiers in Immunology

Tissue-Resident Memory CD8+ T Cells: From Phenotype to Function

(2018) David J. Topham et al.   Frontiers in Immunology

Influenza A Virus Infection Causes Chronic Lung Disease Linked to Sites of Active Viral RNA Remnants

(2018) Shamus P. Keeler et al.   JOURNAL OF IMMUNOLOGY

Genealogy, Dendritic Cell Priming, and Differentiation of Tissue-Resident Memory CD8+ T Cells

(2018) Michel Enamorado et al.   Frontiers in Immunology

Armed and Ready: Transcriptional Regulation of Tissue-Resident Memory CD8 T Cells

(2018) Felix M. Behr et al.   Frontiers in Immunology

Trained Immunity and Local Innate Immune Memory in the Lung

(2018) Mihai G. Netea et al.   CELL

Induction of Autonomous Memory Alveolar Macrophages Requires T Cell Help and Is Critical to Trained Immunity

(2018) Yushi Yao et al.   CELL

Cutting Edge: Tissue-Resident Memory T Cells Generated by Multiple Immunizations or Localized Deposition Provide Enhanced Immunity

(2017) Brooke Davies et al.   JOURNAL OF IMMUNOLOGY

Persistence in Temporary Lung Niches: A Survival Strategy of Lung-Resident Memory CD8+ T Cells

(2017) Shiki Takamura   VIRAL IMMUNOLOGY

Local Inflammatory Cues Regulate Differentiation and Persistence of CD8 + Tissue-Resident Memory T Cells

(2017) Tessa Bergsbaken et al.   Cell Reports

B7-H1 Influences the Accumulation of Virus-Specific Tissue Resident Memory T Cells in the Central Nervous System

(2017) Kevin D. Pavelko et al.   Frontiers in Immunology

Optimal Generation of Tissue-Resident but Not Circulating Memory T Cells during Viral Infection Requires Crosspriming by DNGR-1 + Dendritic Cells

(2016) Salvador Iborra et al.   IMMUNITY

Specific niches for lung-resident memory CD8 + T cells at the site of tissue regeneration enable CD69-independent maintenance

(2016) Shiki Takamura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Context-Dependent Role for IL-21 in Modulating the Differentiation, Distribution, and Abundance of Effector and Memory CD8 T Cell Subsets

(2016) Yuan Tian et al.   JOURNAL OF IMMUNOLOGY

Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β

(2016) Javed Mohammed et al.   NATURE IMMUNOLOGY

The Effects of Acute Neutrophil Depletion on Resolution of Acute Influenza Infection, Establishment of Tissue Resident Memory (TRM), and Heterosubtypic Immunity

(2016) Emma C. Reilly et al.   PLoS One

CD301b+ dendritic cells stimulate tissue-resident memory CD8+ T cells to protect against genital HSV-2

(2016) Haina Shin et al.   Nature Communications

A Distinct Lung-Interstitium-Resident Memory CD8 + T Cell Subset Confers Enhanced Protection to Lower Respiratory Tract Infection

(2016) Pavlo Gilchuk et al.   Cell Reports

Tissue-Resident CD169 + Macrophages Form a Crucial Front Line against Plasmodium Infection

(2016) Pravesh Gupta et al.   Cell Reports

Smad4 Promotes Differentiation of Effector and Circulating Memory CD8 T Cells but Is Dispensable for Tissue-Resident Memory CD8 T Cells

(2015) Yinghong Hu et al.   JOURNAL OF IMMUNOLOGY

Tissue-Resident Memory T Cells and Fixed Immune Surveillance in Nonlymphoid Organs

(2015) Francis R. Carbone   JOURNAL OF IMMUNOLOGY

Antibody-targeted vaccination to lung dendritic cells generates tissue-resident memory CD8 T cells that are highly protective against influenza virus infection

(2015) L M Wakim et al.   Mucosal Immunology

Proinflammatory microenvironments within the intestine regulate the differentiation of tissue-resident CD8+ T cells responding to infection

(2015) Tessa Bergsbaken et al.   NATURE IMMUNOLOGY

Hair follicle–derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma

(2015) Takeya Adachi et al.   NATURE MEDICINE

Transforming growth factor-β signaling is constantly shaping memory T-cell population

(2015) Chaoyu Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutrophil trails guide influenza-specific CD8+ T cells in the airways

(2015) K. Lim et al.   SCIENCE

Intestinal CD169+ macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes

(2015) Kenichi Asano et al.   Nature Communications

Transient ablation of alveolar macrophages leads to massive pathology of influenza infection without affecting cellular adaptive immunity

(2014) Christina Purnama et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Oral Infection Drives a Distinct Population of Intestinal Resident Memory CD8+ T Cells with Enhanced Protective Function

(2014) Brian S. Sheridan et al.   IMMUNITY

Altered Lymph Node Composition in Diphtheria Toxin Receptor–Based Mouse Models To Ablate Dendritic Cells

(2014) Janneke van Blijswijk et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Resident Memory CD8 T Cells Occupy Frontline Niches in Secondary Lymphoid Organs

(2014) J. M. Schenkel et al.   JOURNAL OF IMMUNOLOGY

Vascular-Resident CD169-Positive Monocytes and Macrophages Control Neutrophil Accumulation in the Kidney with Ischemia-Reperfusion Injury

(2014) K. Karasawa et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Control of pathogenic effector T-cell activities in situ by PD-L1 expression on respiratory inflammatory dendritic cells during respiratory syncytial virus infection

(2014) S Yao et al.   Mucosal Immunology

Resident memory CD8 T cells trigger protective innate and adaptive immune responses

(2014) J. M. Schenkel et al.   SCIENCE

Skin-resident memory CD8+ T cells trigger a state of tissue-wide pathogen alert

(2014) S. Ariotti et al.   SCIENCE

A local macrophage chemokine network sustains protective tissue-resident memory CD4 T cells

(2014) N. Iijima et al.   SCIENCE

Dendritic cell subsets require cis-activation for cytotoxic CD8 T-cell induction

(2014) A Nicole Desch et al.   Nature Communications

Alveolar Macrophages Are Essential for Protection from Respiratory Failure and Associated Morbidity following Influenza Virus Infection

(2014) Christoph Schneider et al.   PLoS Pathogens

Flow Cytometric Analysis of Macrophages and Dendritic Cell Subsets in the Mouse Lung

(2013) Alexander V. Misharin et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Advantages and limitations of mouse models to deplete dendritic cells

(2013) Janneke van Blijswijk et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human CD1c+ Dendritic Cells Drive the Differentiation of CD103+ CD8+ Mucosal Effector T Cells via the Cytokine TGF-β

(2013) Chun I. Yu et al.   IMMUNITY

Transforming Growth Factor-β Signaling Controls the Formation and Maintenance of Gut-Resident Memory T Cells by Regulating Migration and Retention

(2013) Nu Zhang et al.   IMMUNITY

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

Splenic Priming of Virus-Specific CD8 T Cells following Influenza Virus Infection

(2013) D. L. Turner et al.   JOURNAL OF VIROLOGY

Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells

(2013) Cara N Skon et al.   NATURE IMMUNOLOGY

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

(2013) Laura K Mackay et al.   NATURE IMMUNOLOGY

Resident CD8+ and Migratory CD103+ Dendritic Cells Control CD8 T Cell Immunity during Acute Influenza Infection

(2013) Jason Waithman et al.   PLoS One

Memory T Cell Subsets, Migration Patterns, and Tissue Residence

(2012) Scott N. Mueller et al.   Annual Review of Immunology

Derivation and Maintenance of Virtual Memory CD8 T Cells

(2012) A. D. Akue et al.   JOURNAL OF IMMUNOLOGY

Priming with very low-affinity peptide ligands gives rise to CD8+ T-cell effectors with enhanced function but with greater susceptibility to transforming growth factor (TGF)β-mediated suppression

(2011) Jeremy A. O’Sullivan et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Different patterns of peripheral migration by memory CD4+ and CD8+ T cells

(2011) Thomas Gebhardt et al.   NATURE

Cross-dressed dendritic cells drive memory CD8+ T-cell activation after viral infection

(2011) Linda M. Wakim et al.   NATURE

Gene Regulation and Chromatin Remodeling by IL-12 and Type I IFN in Programming for CD8 T Cell Effector Function and Memory

(2009) P. Agarwal et al.   JOURNAL OF IMMUNOLOGY

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

(2009) Thomas Gebhardt et al.   NATURE IMMUNOLOGY

Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10

(2009) Jie Sun et al.   NATURE MEDICINE

Effective collaboration between marginal metallophilic macrophages and CD8+ dendritic cells in the generation of cytotoxic T cells

(2009) R. Backer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA