The Mitochondrial Chaperone TRAP1 as a Candidate Target of Oncotherapy
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Title
The Mitochondrial Chaperone TRAP1 as a Candidate Target of Oncotherapy
Authors
Keywords
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Journal
Frontiers in Oncology
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-01-26
DOI
10.3389/fonc.2020.585047
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Note: Only part of the references are listed.- TRAP1 is a predictive biomarker of platinum-based adjuvant chemotherapy benefits in patients with resected lung adenocarcinoma
- (2020) Yuki KUCHITSU et al. BIOMEDICAL RESEARCH-TOKYO
- Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1
- (2020) Hye-Kyung Park et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Tumor Necrosis Factor Receptor-Associated Protein 1 Protects against Mitochondrial Injury by Preventing High Glucose-Induced mPTP Opening in Diabetes
- (2020) Lerong Liu et al. Oxidative Medicine and Cellular Longevity
- Rational Design of Allosteric and Selective Inhibitors of the Molecular Chaperone TRAP1
- (2020) Carlos Sanchez-Martin et al. Cell Reports
- Membrane-Associated Heat Shock Proteins in Oncology: From Basic Research to New Theranostic Targets
- (2020) Maxim Shevtsov et al. Cells
- Cyclophilin D counterbalances mitochondrial calcium uniporter-mediated brain mitochondrial calcium uptake
- (2020) Bei Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mitochondrial chaperone, TRAP1 modulates mitochondrial dynamics and promotes tumor metastasis
- (2020) Shrikant Purushottam Dharaskar et al. MITOCHONDRION
- Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth
- (2019) Ekta Agarwal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of LXR Receptors and Inhibition of TRAP1 Causes Synthetic Lethality in Solid Tumors
- (2019) Trang Thi Thu Nguyen et al. Cancers
- New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting
- (2018) R. Rondanin et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- TRAP1 Regulation of Cancer Metabolism: Dual Role as Oncogene or Tumor Suppressor
- (2018) Danilo Matassa et al. Genes
- Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors
- (2017) Hye-Kyung Park et al. JOURNAL OF MEDICINAL CHEMISTRY
- Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy
- (2017) Rhianna C. Laker et al. Nature Communications
- Absence of Neurofibromin Induces an Oncogenic Metabolic Switch via Mitochondrial ERK-Mediated Phosphorylation of the Chaperone TRAP1
- (2017) Ionica Masgras et al. Cell Reports
- Oxidative metabolism drives inflammation-induced platinum resistance in human ovarian cancer
- (2016) D S Matassa et al. CELL DEATH AND DIFFERENTIATION
- Targeting HSP90/Survivin using a cell permeable structure based peptido-mimetic shepherdin in retinoblastoma
- (2016) Nalini Venkatesan et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Downregulation of TRAP1 sensitizes glioblastoma cells to temozolomide chemotherapy through regulating metabolic reprogramming
- (2016) Jianing Wu et al. NEUROREPORT
- TRAP1 downregulation in human ovarian cancer enhances invasion and epithelial–mesenchymal transition
- (2016) Maria R Amoroso et al. Cell Death & Disease
- TRAP1 controls cell migration of cancer cells in metabolic stress conditions: Correlations with AKT/p70S6K pathways
- (2015) Ilenia Agliarulo et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- TRAP1 Provides Protection Against Myocardial Ischemia-Reperfusion Injury by Ameliorating Mitochondrial Dysfunction
- (2015) Peng Zhang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Berberine induces cell apoptosis through cytochrome C/apoptotic protease-activating factor 1/caspase-3 and apoptosis inducing factor pathway in mouse insulinoma cells
- (2015) Xin Fang et al. Chinese Journal of Integrative Medicine
- Overexpression of mitochondrial Hsp75 protects neural stem cells against microglia-derived soluble factor-induced neurotoxicity by regulating mitochondrial permeability transition pore opening in vitro
- (2015) YAN WANG et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- CXCL5/CXCR2 axis promotes bladder cancer cell migration and invasion by activating PI3K/AKT-induced upregulation of MMP2/MMP9
- (2015) YE GAO et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Aberrantly upregulated TRAP1 is required for tumorigenesis of breast cancer
- (2015) Bo Zhang et al. Oncotarget
- Targeting TRAP1 as a downstream effector of BRAF cytoprotective pathway: a novel strategy for human BRAF-driven colorectal carcinoma
- (2015) Valentina Condelli et al. Oncotarget
- Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells
- (2015) Giulia Guzzo et al. Oncotarget
- Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation
- (2015) Anna Pastò et al. Oncotarget
- Combination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of Bim
- (2014) Hye-Kyung Park et al. BMC CANCER
- Microenvironmental acidosis in carcinogenesis and metastases: new strategies in prevention and therapy
- (2014) Stefano Fais et al. CANCER AND METASTASIS REVIEWS
- TRAP1 Is Involved in BRAF Regulation and Downstream Attenuation of ERK Phosphorylation and Cell-Cycle Progression: A Novel Target for BRAF-Mutated Colorectal Tumors
- (2014) V. Condelli et al. CANCER RESEARCH
- Novel insights into the mitochondrial permeability transition
- (2014) Massimo Bonora et al. CELL CYCLE
- Suppression of tumor necrosis factor receptor-associated protein 1 expression induces inhibition of cell proliferation and tumor growth in human esophageal cancer cells
- (2014) Xin Tian et al. FEBS Journal
- TRAP1 Regulates Proliferation, Mitochondrial Function, and Has Prognostic Significance in NSCLC
- (2014) Jackeline Agorreta et al. MOLECULAR CANCER RESEARCH
- TRAP1-dependent regulation of p70S6K is involved in the attenuation of protein synthesis and cell migration: Relevance in human colorectal tumors
- (2014) Danilo Swann Matassa et al. Molecular Oncology
- Sirtuin1 Over-Expression Does Not Impact Retinal Vascular and Neuronal Degeneration in a Mouse Model of Oxygen-Induced Retinopathy
- (2014) Shaday Michan et al. PLoS One
- The MMP-1, MMP-2, and MMP-9 gene polymorphisms and susceptibility to bladder cancer: a meta-analysis
- (2014) Yulan Yan et al. TUMOR BIOLOGY
- Inhibition of the mitochondrial Hsp90 chaperone network: A novel, efficient treatment strategy for cancer?
- (2013) Markus D. Siegelin CANCER LETTERS
- The Mitochondrial Chaperone TRAP1 Promotes Neoplastic Growth by Inhibiting Succinate Dehydrogenase
- (2013) Marco Sciacovelli et al. Cell Metabolism
- Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells
- (2013) M. Cecilia Caino et al. JOURNAL OF CLINICAL INVESTIGATION
- Resistance to paclitxel in breast carcinoma cells requires a quality control of mitochondrial antiapoptotic proteins by TRAP1
- (2013) Francesca Maddalena et al. Molecular Oncology
- Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis
- (2013) S. Yoshida et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1
- (2013) D S Matassa et al. Cell Death & Disease
- Landscape of the mitochondrial Hsp90 metabolome in tumours
- (2013) Young Chan Chae et al. Nature Communications
- Mitochondrial permeability transition in rat hepatocytes after anoxia/reoxygenation: role of Ca2+-dependent mitochondrial formation of reactive oxygen species
- (2012) Jae-Sung Kim et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components
- (2012) Masato Ogura et al. BIOCHEMICAL JOURNAL
- Altered metabolism in cancer
- (2012) Jason W Locasale et al. BMC BIOLOGY
- Role of TRAP1 and estrogen receptor alpha in patients with ovarian cancer -A study of the OVCAD consortium
- (2012) Stefanie Aust et al. Molecular Cancer
- Combinatorial drug therapy for cancer in the post-genomic era
- (2012) Bissan Al-Lazikani et al. NATURE BIOTECHNOLOGY
- Endoplasmic reticulum–mitochondria contacts: function of the junction
- (2012) Ashley A. Rowland et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The unfolded protein response: controlling cell fate decisions under ER stress and beyond
- (2012) Claudio Hetz NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease
- (2011) B H Kang et al. BRITISH JOURNAL OF CANCER
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- TRAP1 and the proteasome regulatory particle TBP7/Rpt3 interact in the endoplasmic reticulum and control cellular ubiquitination of specific mitochondrial proteins
- (2011) M R Amoroso et al. CELL DEATH AND DIFFERENTIATION
- Mitochondrial TRAP1 regulates the unfolded protein response in the endoplasmic reticulum
- (2011) Kana Takemoto et al. NEUROCHEMISTRY INTERNATIONAL
- Molecular signature of response and potential pathways related to resistance to the HSP90 inhibitor, 17AAG, in breast cancer
- (2010) Magdalena Zajac et al. BMC Medical Genomics
- Tumor necrosis factor receptor-associated protein 1(TRAP1) regulates genes involved in cell cycle and metastases
- (2010) Dongxia Liu et al. CANCER LETTERS
- Mitochondrial Chaperone Trap1 and the Calcium Binding Protein Sorcin Interact and Protect Cells against Apoptosis Induced by Antiblastic Agents
- (2010) M. Landriscina et al. CANCER RESEARCH
- Hypoxia and energetic tumour metabolism
- (2010) M Christiane Brahimi-Horn et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Mitochondrial chaperone tumour necrosis factor receptor-associated protein 1 protects cardiomyocytes from hypoxic injury by regulating mitochondrial permeability transition pore opening
- (2010) Fei Xiang et al. FEBS Journal
- Targeting heat shock protein 72 enhances Hsp90 inhibitor-induced apoptosis in myeloma
- (2010) E L Davenport et al. LEUKEMIA
- Global Targeting of Subcellular Heat Shock Protein-90 Networks for Therapy of Glioblastoma
- (2010) M. D. Siegelin et al. MOLECULAR CANCER THERAPEUTICS
- Cytoprotective Mitochondrial Chaperone TRAP-1 As a Novel Molecular Target in Localized and Metastatic Prostate Cancer
- (2009) Irwin Leav et al. AMERICAN JOURNAL OF PATHOLOGY
- TRAP1, a novel mitochondrial chaperone responsible for multi-drug resistance and protection from apoptotis in human colorectal carcinoma cells
- (2009) Eleonora Costantino et al. CANCER LETTERS
- Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90
- (2009) Byoung Heon Kang et al. JOURNAL OF CLINICAL INVESTIGATION
- Apoptosis in animal models of virus-induced disease
- (2009) Penny Clarke et al. NATURE REVIEWS MICROBIOLOGY
- Brick by brick: metabolism and tumor cell growth
- (2008) Ralph J DeBerardinis et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Transcriptional patterns, biomarkers and pathways characterizing nasopharyngeal carcinoma of Southern China
- (2008) Weiyi Fang et al. Journal of Translational Medicine
- Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
- (2008) D. R. Wise et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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