The Era of Radiogenomics in Precision Medicine: An Emerging Approach to Support Diagnosis, Treatment Decisions, and Prognostication in Oncology

Cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Radiomics: A primer for the radiation oncologist

(2020) J.-E. Bibault et al.   Cancer Radiotherapie

Reliability and prognostic value of radiomic features are highly dependent on choice of feature extraction platform

(2020) Isabella Fornacon-Wood et al.   EUROPEAN RADIOLOGY

Artificial intelligence radiogenomics for advancing precision and effectiveness in oncologic care (Review)

(2020) Eleftherios Trivizakis et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Machine learning for radiation outcome modeling and prediction

(2020) Yi Luo et al.   MEDICAL PHYSICS

Comprehensive Evaluation of Relapse Risk (CERR) Score for Colorectal Liver Metastases: Development and Validation

(2020) Yijiao Chen et al.   ONCOLOGIST

The Image Biomarker Standardization Initiative: Standardized Quantitative Radiomics for High-Throughput Image-based Phenotyping

(2020) Alex Zwanenburg et al.   RADIOLOGY

Transcriptomics in cancer revealed by Positron Emission Tomography radiomics

(2020) Florent Tixier et al.   Scientific Reports

Don’t dismiss logistic regression: the case for sensible extraction of interactions in the era of machine learning

(2020) Joshua J. Levy et al.   BMC Medical Research Methodology

The Effect of Registration on Voxel-Wise Tofts Model Parameters and Uncertainties from DCE-MRI of Early-Stage Breast Cancer Patients Using 3DSlicer

(2020) Matthew Mouawad et al.   JOURNAL OF DIGITAL IMAGING

CroSSED sequence, a new tool for 3D processing in geosciences using the free software 3DSlicer

(2020) Javier Dorador et al.   Scientific Data

Radiogenomics in Clear Cell Renal Cell Carcinoma: Machine Learning–Based High-Dimensional Quantitative CT Texture Analysis in Predicting PBRM1 Mutation Status

(2019) Burak Kocak et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

Preoperative MRI-radiomics features improve prediction of survival in glioblastoma patients over MGMT methylation status alone

(2019) Florent Tixier et al.   Oncotarget

Predicting Breast Cancer Molecular Subtype with MRI Dataset Utilizing Convolutional Neural Network Algorithm

(2019) Richard Ha et al.   JOURNAL OF DIGITAL IMAGING

NCTN Assessment on Current Applications of Radiomics in Oncology

(2019) Ke Nie et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Renal cell carcinoma: predicting RUNX3 methylation level and its consequences on survival with CT features

(2019) Dongzhi Cen et al.   EUROPEAN RADIOLOGY

Deep Learning Predicts Lung Cancer Treatment Response from Serial Medical Imaging

(2019) Yiwen Xu et al.   CLINICAL CANCER RESEARCH

CT Imaging Characteristics of Non-Small Cell Lung Cancer with Anaplastic Lymphoma Kinase (ALK) Rearrangements: A Systematic Review and Meta-analysis

(2019) Dexter P. Mendoza et al.   Clinical Lung Cancer

Radiogenomics of rectal adenocarcinoma in the era of precision medicine: A pilot study of associations between qualitative and quantitative MRI imaging features and genetic mutations

(2019) Natally Horvat et al.   EUROPEAN JOURNAL OF RADIOLOGY

Prostate Cancer, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology

(2019) James L. Mohler et al.   Journal of the National Comprehensive Cancer Network

Reliability of tumor segmentation in glioblastoma: impact on the robustness of MRI ‐radiomic features

(2019) Florent Tixier et al.   MEDICAL PHYSICS

Radiogenomics in head and neck cancer: correlation of radiomic heterogeneity and somatic mutations in TP53, FAT1 and KMT2D

(2019) Kerstin Zwirner et al.   STRAHLENTHERAPIE UND ONKOLOGIE

Identification and Validation of a Biomarker Signature in Patients With Resectable Pancreatic Cancer via Genome-Wide Screening for Functional Genetic Variants

(2019) Christos Dimitrakopoulos et al.   JAMA Surgery

Radiogenomics: bridging imaging and genomics

(2019) Zuhir Bodalal et al.   Abdominal Radiology

Acute Tumor Transition Angle on Computed Tomography Predicts Chromosomal Instability Status of Primary Gastric Cancer: Radiogenomics Analysis from TCGA and Independent Validation

(2019) Ying-Chieh Lai et al.   Cancers

Deep learning for identifying radiogenomic associations in breast cancer

(2019) Zhe Zhu et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Impact of image preprocessing on the scanner dependence of multi-parametric MRI radiomic features and covariate shift in multi-institutional glioblastoma datasets

(2019) Hyemin Um et al.   PHYSICS IN MEDICINE AND BIOLOGY

Prediction of Aneurysm Stability Using a Machine Learning Model Based on PyRadiomics-Derived Morphological Features

(2019) QingLin Liu et al.   STROKE

Radiogenomics of breast cancer using dynamic contrast enhanced MRI and gene expression profiling

(2019) Albert C. Yeh et al.   CANCER IMAGING

Evolving the pulmonary nodules diagnosis from classical approaches to deep learning-aided decision support: three decades’ development course and future prospect

(2019) Bo Liu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Deep learning analysis of breast MRIs for prediction of occult invasive disease in ductal carcinoma in situ

(2019) Zhe Zhu et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Radiomics of 18F-FDG PET/CT images predicts clinical benefit of advanced NSCLC patients to checkpoint blockade immunotherapy

(2019) Wei Mu et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Technical Note: An IBEX adaption toward image biomarker standardization

(2019) Andrea Bettinelli et al.   MEDICAL PHYSICS

18F-FDG PET/CT Uptake Classification in Lymphoma and Lung Cancer by Using Deep Convolutional Neural Networks

(2019) Ludovic Sibille et al.   RADIOLOGY

Is There an Independent Role of TERT and NF1 in High Grade Gliomas?

(2019) Evangelia Razis et al.   Translational Oncology

Deep-Learning Convolutional Neural Networks Accurately Classify Genetic Mutations in Gliomas

(2018) P. Chang et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

CT Features of Ovarian Tumors: Defining Key Differences Between Serous Borderline Tumors and Low-Grade Serous Carcinomas

(2018) Stephanie Nougaret et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

Precision Medicine from a Public Health Perspective

(2018) Ramya Ramaswami et al.   Annual Review of Public Health

BRCA1/2 testing: therapeutic implications for breast cancer management

(2018) Nadine M. Tung et al.   BRITISH JOURNAL OF CANCER

Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics

(2018) Li Ding et al.   CELL

The FAIR guiding principles for data stewardship: fair enough?

(2018) Martin Boeckhout et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Radiogenomics correlation between MR imaging features and major genetic profiles in glioblastoma

(2018) Eun Kyoung Hong et al.   EUROPEAN RADIOLOGY

Machine learning algorithms for outcome prediction in (chemo)radiotherapy: An empirical comparison of classifiers

(2018) Timo M. Deist et al.   MEDICAL PHYSICS

Technical Note: Extension of CERR for computational radiomics: A comprehensive MATLAB platform for reproducible radiomics research

(2018) Aditya P. Apte et al.   MEDICAL PHYSICS

Non–Small Cell Lung Cancer Radiogenomics Map Identifies Relationships between Molecular and Imaging Phenotypes with Prognostic Implications

(2018) Mu Zhou et al.   RADIOLOGY

MR Imaging Features of Retinoblastoma: Association with Gene Expression Profiles

(2018) Robin W. Jansen et al.   RADIOLOGY

Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma

(2018) Diana Miao et al.   SCIENCE

Genome sequencing analysis of liver cancer for precision medicine

(2018) Hidewaki Nakagawa et al.   SEMINARS IN CANCER BIOLOGY

Appearance Constrained Semi-Automatic Segmentation from DCE-MRI is Reproducible and Feasible for Breast Cancer Radiomics: A Feasibility Study

(2018) Harini Veeraraghavan et al.   Scientific Reports

ALK- rearrangement in non-small-cell lung cancer (NSCLC)

(2018) Xue Du et al.   Thoracic Cancer

Guidelines and Experience Using Imaging Biomarker Explorer (IBEX) for Radiomics

(2018) Rachel B. Ger et al.   Jove-Journal of Visualized Experiments

MRI features predict p53 status in lower-grade gliomas via a machine-learning approach

(2018) Yiming Li et al.   NeuroImage-Clinical

Radiomics and radiogenomics of prostate cancer

(2018) Clayton P. Smith et al.   Abdominal Radiology

Machine Learning and Radiogenomics: Lessons Learned and Future Directions

(2018) John Kang et al.   Frontiers in Oncology

Genomic Deletion at 10q23 in Prostate Cancer: More Than PTEN Loss?

(2018) Raghavendra Tejo Karthik Poluri et al.   Frontiers in Oncology

A Deep Look into the Future of Quantitative Imaging in Oncology: A Statement of Working Principles and Proposal for Change

(2018) Olivier Morin et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Differentiation of clear cell and non-clear cell renal cell carcinomas by all-relevant radiomics features from multiphase CT: a VHL mutation perspective

(2018) Zhi-Cheng Li et al.   EUROPEAN RADIOLOGY

Radiogenomics for Precision Medicine With a Big Data Analytics Perspective

(2018) Andreas S. Panayides et al.   IEEE Journal of Biomedical and Health Informatics

Prognostic value and molecular correlates of a CT image-based quantitative pleural contact index in early stage NSCLC

(2017) Juheon Lee et al.   EUROPEAN RADIOLOGY

Imaging-based surrogate markers of transcriptome subclasses and signatures in hepatocellular carcinoma: preliminary results

(2017) Bachir Taouli et al.   EUROPEAN RADIOLOGY

A novel representation of inter-site tumour heterogeneity from pre-treatment computed tomography textures classifies ovarian cancers by clinical outcome

(2017) Hebert Alberto Vargas et al.   EUROPEAN RADIOLOGY

Volume of high-risk intratumoral subregions at multi-parametric MR imaging predicts overall survival and complements molecular analysis of glioblastoma

(2017) Yi Cui et al.   EUROPEAN RADIOLOGY

Radiogenomic Analysis of Oncological Data: A Technical Survey

(2017) Mariarosaria Incoronato et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Background, current role, and potential applications of radiogenomics

(2017) Katja Pinker et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

The preliminary radiogenomics association between MR perfusion imaging parameters and genomic biomarkers, and their predictive performance of overall survival in patients with glioblastoma

(2017) Xiang Liu et al.   JOURNAL OF NEURO-ONCOLOGY

Radiogenomics of lower-grade glioma: algorithmically-assessed tumor shape is associated with tumor genomic subtypes and patient outcomes in a multi-institutional study with The Cancer Genome Atlas data

(2017) Maciej A. Mazurowski et al.   JOURNAL OF NEURO-ONCOLOGY

Multiparametric MRI in the Detection of Clinically Significant Prostate Cancer

(2017) Jurgen J. Fütterer   KOREAN JOURNAL OF RADIOLOGY

Radiomics: the bridge between medical imaging and personalized medicine

(2017) Philippe Lambin et al.   Nature Reviews Clinical Oncology

Application of the 3D slicer chest imaging platform segmentation algorithm for large lung nodule delineation

(2017) Stephen S. F. Yip et al.   PLoS One

Heterogeneous Enhancement Patterns of Tumor-adjacent Parenchyma at MR Imaging Are Associated with Dysregulated Signaling Pathways and Poor Survival in Breast Cancer

(2017) Jia Wu et al.   RADIOLOGY

Radiogenomics Map: A Novel Approach for Noninvasive Identification of Molecular Properties?

(2017) Sizhe Chen et al.   RADIOLOGY

High-Grade Serous Ovarian Cancer: Associations between BRCA Mutation Status, CT Imaging Phenotypes, and Clinical Outcomes

(2017) Stephanie Nougaret et al.   RADIOLOGY

Epidemiology and Molecular Biology of Head and Neck Cancer

(2017) Adriana Jou et al.   Oncology Research and Treatment

BRCA mutation in ovarian cancer: testing, implications and treatment considerations

(2017) Robert T. Neff et al.   Therapeutic Advances in Medical Oncology

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015

(2017) et al.   JAMA Oncology

Exploitation of Gene Expression and Cancer Biomarkers in Paving the Path to Era of Personalized Medicine

(2017) Hala Fawzy Mohamed Kamel et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Predictive radiogenomics modeling of EGFR mutation status in lung cancer

(2017) Olivier Gevaert et al.   Scientific Reports

Delta-radiomics features for the prediction of patient outcomes in non–small cell lung cancer

(2017) Xenia Fave et al.   Scientific Reports

Quantitative Multiparametric MRI Features and PTEN Expression of Peripheral Zone Prostate Cancer: A Pilot Study

(2016) Stephanie M. McCann et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

Prediction of KRAS Mutation in Rectal Cancer Using MRI

(2016) YU RI SHIN et al.   ANTICANCER RESEARCH

Big Data and machine learning in radiation oncology: State of the art and future prospects

(2016) Jean-Emmanuel Bibault et al.   CANCER LETTERS

Radiogenomics – current status, challenges and future directions

(2016) Christian Nicolaj Andreassen et al.   CANCER LETTERS

Evidence-Based Diagnosis, Staging, and Treatment of Patients With Hepatocellular Carcinoma

(2016) Jordi Bruix et al.   GASTROENTEROLOGY

Low-grade serous ovarian cancer: A review

(2016) Anis Kaldawy et al.   GYNECOLOGIC ONCOLOGY

Periostin (POSTN) Regulates Tumor Resistance to Antiangiogenic Therapy in Glioma Models

(2016) S. Y. Park et al.   MOLECULAR CANCER THERAPEUTICS

Repeatability of Radiomic Features in Non-Small-Cell Lung Cancer [18F]FDG-PET/CT Studies: Impact of Reconstruction and Delineation

(2016) Floris H. P. van Velden et al.   MOLECULAR IMAGING AND BIOLOGY

Radiogenomics to characterize regional genetic heterogeneity in glioblastoma

(2016) Leland S. Hu et al.   NEURO-ONCOLOGY

Radiogenomics of Glioblastoma: Machine Learning–based Classification of Molecular Characteristics by Using Multiparametric and Multiregional MR Imaging Features

(2016) Philipp Kickingereder et al.   RADIOLOGY

Radiomics: Images Are More than Pictures, They Are Data

(2016) Robert J. Gillies et al.   RADIOLOGY

Emergence of the Noncoding Cancer Genome: A Target of Genetic and Epigenetic Alterations

(2016) S. Zhou et al.   Cancer Discovery

Addressing intra-tumoral heterogeneity and therapy resistance

(2016) Brad Rybinski et al.   Oncotarget

Association of multiparametric MRI quantitative imaging features with prostate cancer gene expression in MRI-targeted prostate biopsies

(2016) Radka Stoyanova et al.   Oncotarget

The Potential of Radiomic-Based Phenotyping in Precision Medicine

(2016) Hugo J. W. L. Aerts   JAMA Oncology

Assessing Discriminative Performance at External Validation of Clinical Prediction Models

(2016) Daan Nieboer et al.   PLoS One

Defining a Radiomic Response Phenotype: A Pilot Study using targeted therapy in NSCLC

(2016) Hugo J. W. L. Aerts et al.   Scientific Reports

CT textural analysis of hepatic metastatic colorectal cancer: pre-treatment tumor heterogeneity correlates with pathology and clinical outcomes

(2015) Meghan G. Lubner et al.   ABDOMINAL IMAGING

Radiogenomics of clear cell renal cell carcinoma: preliminary findings of The Cancer Genome Atlas–Renal Cell Carcinoma (TCGA–RCC) Imaging Research Group

(2015) Atul B. Shinagare et al.   ABDOMINAL IMAGING

Distinct clinicopathological phenotype of hepatocellular carcinoma with ethoxybenzyl-magnetic resonance imaging hyperintensity: association with gene expression signature

(2015) Tomoya Miura et al.   AMERICAN JOURNAL OF SURGERY

Genetic Alterations in Colorectal Cancer Have Different Patterns on 18F-FDG PET/CT

(2015) Shang-Wen Chen et al.   CLINICAL NUCLEAR MEDICINE

A computed tomography radiogenomic biomarker predicts microvascular invasion and clinical outcomes in hepatocellular carcinoma

(2015) Sudeep Banerjee et al.   HEPATOLOGY

Machine Learning Approaches for Predicting Radiation Therapy Outcomes: A Clinician's Perspective

(2015) John Kang et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Breast cancer subtype intertumor heterogeneity: MRI-based features predict results of a genomic assay

(2015) Elizabeth J. Sutton et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

MRI phenotype of breast cancer: Kinetic assessment for molecular subtypes

(2015) Eric Blaschke et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Computational approach to radiogenomics of breast cancer: Luminal A and luminal B molecular subtypes are associated with imaging features on routine breast MRI extracted using computer vision algorithms

(2015) Lars J. Grimm et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Comprehensive genomic characterization of head and neck squamous cell carcinomas

(2015)   NATURE

Deep learning

(2015) Yann LeCun et al.   NATURE

Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth

(2015) Wenchao Zhou et al.   NATURE CELL BIOLOGY

Metabolic consequences of oncogenic IDH mutations

(2015) Seth J. Parker et al.   PHARMACOLOGY & THERAPEUTICS

Breast Cancer: Radiogenomic Biomarker Reveals Associations among Dynamic Contrast-enhanced MR Imaging, Long Noncoding RNA, and Metastasis

(2015) Shota Yamamoto et al.   RADIOLOGY

IDH mutation status is associated with a distinct hypoxia/angiogenesis transcriptome signature which is non-invasively predictable with rCBV imaging in human glioma

(2015) Philipp Kickingereder et al.   Scientific Reports

Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): the TRIPOD statement

(2015) G. S. Collins et al.   BMJ-British Medical Journal

Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): the TRIPOD statement

(2015) G. S. Collins et al.   BMJ-British Medical Journal

Retinoblastoma

(2015) Helen Dimaras et al.   Nature Reviews Disease Primers

The Global Burden of Cancer 2013

(2015) Christina Fitzmaurice et al.   JAMA Oncology

Cholangiocarcinoma: Correlation between Molecular Profiling and Imaging Phenotypes

(2015) Eran Sadot et al.   PLoS One

Prognostic Impact of Microscopic Vessel Invasion and Visceral Pleural Invasion in Non–Small Cell Lung Cancer

(2014) Shinya Neri et al.   ANNALS OF SURGERY

Regional Chemotherapy for Unresectable Intrahepatic Cholangiocarcinoma: A Potential Role for Dynamic Magnetic Resonance Imaging as an Imaging Biomarker and a Survival Update from Two Prospective Clinical Trials

(2014) Ioannis T. Konstantinidis et al.   ANNALS OF SURGICAL ONCOLOGY

Radiogenomics: Radiobiology Enters the Era of Big Data and Team Science

(2014) Barry S. Rosenstein et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Multifunctional Imaging Signature for V-KI-RAS2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutations in Colorectal Cancer

(2014) K. A. Miles et al.   JOURNAL OF NUCLEAR MEDICINE

Comprehensive molecular characterization of gastric adenocarcinoma

(2014) Adam J. Bass et al.   NATURE

Quantitative multimodality imaging in cancer research and therapy

(2014) Thomas E. Yankeelov et al.   Nature Reviews Clinical Oncology

Robust Radiomics Feature Quantification Using Semiautomatic Volumetric Segmentation

(2014) Chintan Parmar et al.   PLoS One

Radiogenomic Analysis of Breast Cancer: Luminal B Molecular Subtype Is Associated with Enhancement Dynamics at MR Imaging

(2014) Maciej A. Mazurowski et al.   RADIOLOGY

Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach

(2014) Hugo J. W. L. Aerts et al.   Nature Communications

Renal cell carcinoma

(2014) E. Jonasch et al.   BMJ-British Medical Journal

Genetic markers associated with early cancer-specific mortality following prostatectomy

(2013) Wennuan Liu et al.   CANCER

Molecular Pathways: JAK/STAT Pathway: Mutations, Inhibitors, and Resistance

(2013) A. Quintas-Cardama et al.   CLINICAL CANCER RESEARCH

Effects on survival of BAP1 and PBRM1 mutations in sporadic clear-cell renal-cell carcinoma: a retrospective analysis with independent validation

(2013) Payal Kapur et al.   LANCET ONCOLOGY

NF-κB protein expression associates with 18F-FDG PET tumor uptake in non-small cell lung cancer: A radiogenomics validation study to understand tumor metabolism

(2013) Viswam S. Nair et al.   LUNG CANCER

A clear picture of renal cell carcinoma

(2013) A Ari Hakimi et al.   NATURE GENETICS

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2006-2010

(2013) Q. T. Ostrom et al.   NEURO-ONCOLOGY

Illuminating Radiogenomic Characteristics of Glioblastoma Multiforme through Integration of MR Imaging, Messenger RNA Expression, and DNA Copy Number Variation

(2013) Neema Jamshidi et al.   RADIOLOGY

Radiogenomics of Clear Cell Renal Cell Carcinoma: Associations between CT Imaging Features and Mutations

(2013) Christoph A. Karlo et al.   RADIOLOGY

Volumetric CT-based segmentation of NSCLC using 3D-Slicer

(2013) Emmanuel Rios Velazquez et al.   Scientific Reports

Radiogenomic Analysis of Breast Cancer Using MRI: A Preliminary Study to Define the Landscape

(2012) Shota Yamamoto et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

EGFRmutation testing in lung cancer: a review of available methods and their use for analysis of tumour tissue and cytology samples

(2012) Gillian Ellison et al.   JOURNAL OF CLINICAL PATHOLOGY

3D Slicer as an image computing platform for the Quantitative Imaging Network

(2012) Andriy Fedorov et al.   MAGNETIC RESONANCE IMAGING

Non–Small Cell Lung Cancer: Histopathologic Correlates for Texture Parameters at CT

(2012) Balaji Ganeshan et al.   RADIOLOGY

Carcinoma of the stomach: A review of epidemiology, pathogenesis, molecular genetics and chemoprevention

(2012) Siddavaram Nagini   World Journal of Gastrointestinal Oncology

EGFR Mutations and Lung Cancer

(2011) Gilda da Cunha Santos et al.   Annual Review of Pathology-Mechanisms of Disease

Association of BRCA1 and BRCA2 Mutations With Survival, Chemotherapy Sensitivity, and Gene Mutator Phenotype in Patients With Ovarian Cancer

(2011) Da Yang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

PTEN Signaling pathways in glioblastoma

(2010) Dimpy Koul   CANCER BIOLOGY & THERAPY

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Computerized segmentation and measurement of malignant pleural mesothelioma

(2010) William F. Sensakovic et al.   MEDICAL PHYSICS

Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma

(2010) S L Cooke et al.   ONCOGENE

RUNX3 is multifunctional in carcinogenesis of multiple solid tumors

(2010) L S H Chuang et al.   ONCOGENE

The Incidence and Epidemiology of Hepatocellular Carcinoma: A Global and Regional Perspective

(2010) A. P. Venook et al.   ONCOLOGIST

Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas

(2009) Christian Hartmann et al.   ACTA NEUROPATHOLOGICA

Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship

(2009) Julian R. Molina et al.   MAYO CLINIC PROCEEDINGS

Breast Cancer Molecular Subtypes in Patients With Locally Advanced Disease: Impact on Prognosis, Patterns of Recurrence, and Response to Therapy

(2009) Kathryn E. Huber et al.   SEMINARS IN RADIATION ONCOLOGY

New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)

(2008) E.A. Eisenhauer et al.   EUROPEAN JOURNAL OF CANCER

Effect ofBRCA1/2Mutations on Long-Term Survival of Patients With Invasive Ovarian Cancer: The National Israeli Study of Ovarian Cancer

(2007) Angela Chetrit et al.   JOURNAL OF CLINICAL ONCOLOGY