Radiogenomics in head and neck cancer: correlation of radiomic heterogeneity and somatic mutations in TP53, FAT1 and KMT2D

Tumor mutational load predicts survival after immunotherapy across multiple cancer types

(2019) Robert M. Samstein et al.   NATURE GENETICS

Definitive radiochemotherapy or initial surgery for oropharyngeal cancer

(2019) Anouchka Modesto et al.   STRAHLENTHERAPIE UND ONKOLOGIE

Strelka2: fast and accurate calling of germline and somatic variants

(2018) Sangtae Kim et al.   NATURE METHODS

Tumor volume as a prognostic marker in p16-positive and p16-negative oropharyngeal cancer patients treated with definitive intensity-modulated radiotherapy

(2018) Timo Carpén et al.   STRAHLENTHERAPIE UND ONKOLOGIE

Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations

(2018) David Tamborero et al.   Genome Medicine

FAT1 modulates EMT and stemness genes expression in hypoxic glioblastoma

(2017) Chitrangda Srivastava et al.   INTERNATIONAL JOURNAL OF CANCER

Targeted next-generation sequencing identifies molecular subgroups in squamous cell carcinoma of the head and neck with distinct outcome after concurrent chemoradiation

(2016) I. Tinhofer et al.   ANNALS OF ONCOLOGY

FAT1: a potential target for monoclonal antibody therapy in colon cancer

(2016) Piero Pileri et al.   BRITISH JOURNAL OF CANCER

Association between FAT1 mutation and overall survival in patients with human papillomavirus-negative head and neck squamous cell carcinoma

(2016) Ki Tae Kim et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

HPV status, cancer stem cell marker expression, hypoxia gene signatures and tumour volume identify good prognosis subgroups in patients with HNSCC after primary radiochemotherapy: A multicentre retrospective study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG)

(2016) Annett Linge et al.   RADIOTHERAPY AND ONCOLOGY

External validation of a prognostic CT-based radiomic signature in oropharyngeal squamous cell carcinoma

(2015) Ralph T. H. Leijenaar et al.   ACTA ONCOLOGICA

Comprehensive genomic characterization of head and neck squamous cell carcinomas

(2015)   NATURE

Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach

(2014) Hugo J. W. L. Aerts et al.   Nature Communications

Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation

(2013) Luc G T Morris et al.   NATURE GENETICS

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

Predicting outcomes in radiation oncology—multifactorial decision support systems

(2012) Philippe Lambin et al.   Nature Reviews Clinical Oncology

FAT1 acts as an upstream regulator of oncogenic and inflammatory pathways, via PDCD4, in glioma cells

(2012) B Dikshit et al.   ONCOGENE

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Human FAT1 cadherin controls cell migration and invasion of oral squamous cell carcinoma through the localization of β-catenin

(2011) Tatsuhiko Miyazaki   ONCOLOGY REPORTS

Tumor volume as prognostic factor in chemoradiation for advanced head and neck cancer

(2010) Joost L. Knegjens et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 93 randomised trials and 17,346 patients

(2009) Jean-Pierre Pignon et al.   RADIOTHERAPY AND ONCOLOGY