The Inflammatory Cytokine IL-3 Hampers Cardioprotection Mediated by Endothelial Cell-Derived Extracellular Vesicles Possibly via Their Protein Cargo

Ischemia Reperfusion Injury: Mechanisms of Damage/Protection and Novel Strategies for Cardiac Recovery/Regeneration

(2019) Andrea Caccioppo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Contrasting Role of Extracellular Vesicles in Vascular Inflammation and Tissue Repair

(2019) Silvia Oggero et al.   Frontiers in Pharmacology

Protective effects of circulating microvesicles derived from ischemic preconditioning on myocardial ischemia/reperfusion injury in rats by inhibiting endoplasmic reticulum stress

(2018) Miao Liu et al.   APOPTOSIS

Intra-Cardiac Release of Extracellular Vesicles Shapes Inflammation Following Myocardial InfarctionNovelty and Significance

(2018) Xavier Loyer et al.   CIRCULATION RESEARCH

Metaflammation: Tissue-Specific Alterations of the NLRP3 Inflammasome Platform in Metabolic Syndrome

(2018) Raffaella Mastrocola et al.   CURRENT MEDICINAL CHEMISTRY

Role of cytokines and inflammation in heart function during health and disease

(2018) Monika Bartekova et al.   HEART FAILURE REVIEWS

Cardiac macrophage biology in the steady-state heart, the aging heart, and following myocardial infarction

(2018) Yonggang Ma et al.   Translational Research

Plasma exosomes induced by remote ischaemic preconditioning attenuate myocardial ischaemia/reperfusion injury by transferring miR-24

(2018) Wen Minghua et al.   Cell Death & Disease

α-Cyclodextrin and α-Cyclodextrin Polymers as Oxygen Nanocarriers to Limit Hypoxia/Reoxygenation Injury: Implications from an In Vitro Model

(2018) Saveria Femminò et al.   Polymers

Cardioprotective Properties of Human Platelets Are Lost in Uncontrolled Diabetes Mellitus: A Study in Isolated Rat Hearts

(2018) Isabella Russo et al.   Frontiers in Physiology

Systematic Methodological Evaluation of a Multiplex Bead-Based Flow Cytometry Assay for Detection of Extracellular Vesicle Surface Signatures

(2018) Oscar P. B. Wiklander et al.   Frontiers in Immunology

Astroglial DJ-1 over-expression up-regulates proteins involved in redox regulation and is neuroprotective in vivo

(2018) Ann Kristin Frøyset et al.   Redox Biology

Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection

(2018) Hans Erik Bøtker et al.   BASIC RESEARCH IN CARDIOLOGY

Endothelial cells release cardioprotective exosomes that may contribute to ischaemic preconditioning

(2018) Sean M. Davidson et al.   Scientific Reports

Effects of tumor necrosis factor-α-induced exosomes on the endothelial cellular behavior, metabolism and bioenergetics

(2018) Bingwei Li et al.   MICROCIRCULATION

Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication

(2018) Mathilde Mathieu et al.   NATURE CELL BIOLOGY

Coronary Microvascular Injury in Reperfused Acute Myocardial Infarction: A View From an Integrative Perspective

(2018) Murat Sezer et al.   Journal of the American Heart Association

Obestatin regulates cardiovascular function and promotes cardioprotection through the nitric oxide pathway

(2017) Claudia Penna et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Upregulation of connexin43 by glucose deprivation in H9c2 cells via the extracellular signal‑regulated kinase/mitogen‑activated protein kinase signaling pathway

(2017) Guangyu Wang et al.   Molecular Medicine Reports

The HSP90 chaperone machinery

(2017) Florian H. Schopf et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Microvesicles derived from hypoxia/reoxygenation-treated human umbilical vein endothelial cells promote apoptosis and oxidative stress in H9c2 cardiomyocytes

(2016) Qi Zhang et al.   BMC CELL BIOLOGY

Maladaptive Modulations of NLRP3 Inflammasome and Cardioprotective Pathways Are Involved in Diet-Induced Exacerbation of Myocardial Ischemia/Reperfusion Injury in Mice

(2016) Raffaella Mastrocola et al.   Oxidative Medicine and Cellular Longevity

Epidemiological aspects of heart diseases

(2016) Aimin Shi et al.   Experimental and Therapeutic Medicine

Activated Stat5 trafficking Via Endothelial Cell-derived Extracellular Vesicles Controls IL-3 Pro-angiogenic Paracrine Action

(2016) Giusy Lombardo et al.   Scientific Reports

Endogenous Cardioprotective Agents: Role in Pre and Postconditioning

(2015) Claudia Penna et al.   CURRENT DRUG TARGETS

Direct Endothelial Nitric Oxide Synthase Activation Provides Atheroprotection in Diabetes-Accelerated Atherosclerosis

(2015) Arpeeta Sharma et al.   DIABETES

Reducing myocardial infarct size: challenges and future opportunities

(2015) Heerajnarain Bulluck et al.   HEART

Time-dependent release of extracellular vesicle subpopulations in tumor CABA I cells

(2015) ILARIA GIUSTI et al.   ONCOLOGY REPORTS

Catestatin Exerts Direct Protective Effects on Rat Cardiomyocytes Undergoing Ischemia/Reperfusion by Stimulating PI3K-Akt-GSK3β Pathway and Preserving Mitochondrial Membrane Potential

(2015) Eleonora Bassino et al.   PLoS One

Cardiac macrophages and their role in ischaemic heart disease

(2014) Stefan Frantz et al.   CARDIOVASCULAR RESEARCH

Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles

(2014) Zoltán Giricz et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The inflammatory response in myocardial injury, repair and remodelling

(2014) Nikolaos G. Frangogiannis   Nature Reviews Cardiology

The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia–reperfusion injury

(2013) Øystein Sandanger et al.   CARDIOVASCULAR RESEARCH

Correction: The MEK-ERK Pathway Is Necessary for Serine Phosphorylation of Mitochondrial STAT3 and Ras-Mediated Transformation

(2013) Daniel J. Gough et al.   PLoS One

Apelin-13 limits infarct size and improves cardiac postischemic mechanical recovery only if given after ischemia

(2011) Raffaella Rastaldo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Possible involvement of caveolin in attenuation of cardioprotective effect of ischemic preconditioning in diabetic rat heart

(2011) Preeti Ajmani et al.   BMC Cardiovascular Disorders

Inflammasome Activation of Cardiac Fibroblasts Is Essential for Myocardial Ischemia/Reperfusion Injury

(2011) Masanori Kawaguchi et al.   CIRCULATION