ADCC against MICA/B Is Mediated against Differentiated Oral and Pancreatic and Not Stem-Like/Poorly Differentiated Tumors by the NK Cells; Loss in Cancer Patients due to Down-Modulation of CD16 Receptor

Prognostic value of peripheral blood natural killer cells in colorectal cancer

(2020) Yan-ping Tang et al.   BMC GASTROENTEROLOGY

EGFR-upregulated LIFR promotes SUCLG2-dependent castration resistance and neuroendocrine differentiation of prostate cancer

(2020) Shian-Ren Lin et al.   ONCOGENE

Bispecific NKG2D-CD3 and NKG2D-CD16 fusion proteins for induction of NK and T cell reactivity against acute myeloid leukemia

(2019) Melanie Märklin et al.   Journal for ImmunoTherapy of Cancer

Post-treatment improvement of NK cell numbers predicts better survival in myeloma patients treated with thalidomide-based regimens

(2019) Jorge Vela-Ojeda et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Anti-Colorectal Cancer Effects of Probiotic-Derived p8 Protein

(2019) Byung Chull An et al.   Genes

Probiotic-Treated Super-Charged NK Cells Efficiently Clear Poorly Differentiated Pancreatic Tumors in Hu-BLT Mice

(2019) Kawaljit Kaur et al.   Cancers

Natural killer cells target and differentiate cancer stem-like cells/undifferentiated tumors: strategies to optimize their growth and expansion for effective cancer immunotherapy

(2018) Kawaljit Kaur et al.   CURRENT OPINION IN IMMUNOLOGY

Super-charged NK cells inhibit growth and progression of stem-like/poorly differentiated oral tumors in vivo in humanized BLT mice; effect on tumor differentiation and response to chemotherapeutic drugs

(2018) Kawaljit Kaur et al.   OncoImmunology

Augmentation of antibody-dependent cellular cytotoxicity with defucosylated monoclonal antibodies in patients with GI-tract cancer

(2017) Takahiro Nakajima et al.   Oncology Letters

Prognostic value of MICA/B in cancers: a systematic review and meta-analysis

(2017) Yijing Zhao et al.   Oncotarget

Endothelial cells express NKG2D ligands and desensitize antitumor NK responses

(2017) Thornton W Thompson et al.   eLife

Differentiation by NK cells is a prerequisite for effective targeting of cancer stem cells/poorly differentiated tumors by chemopreventive and chemotherapeutic drugs

(2017) Anna Kozlowska et al.   Journal of Cancer

MICA Expression Is Regulated by Cell Adhesion and Contact in a FAK/Src-Dependent Manner

(2017) Gerald Moncayo et al.   Frontiers in Immunology

Novel Strategy to Expand Super-Charged NK Cells with Significant Potential to Lyse and Differentiate Cancer Stem Cells: Differences in NK Expansion and Function between Healthy and Cancer Patients

(2017) Kawaljit Kaur et al.   Frontiers in Immunology

The anti-SLAMF7 antibody elotuzumab mediates NK cell activation through both CD16-dependent and –independent mechanisms

(2017) Tatiana Pazina et al.   OncoImmunology

Impaired NK cell recognition of vemurafenib-treated melanoma cells is overcome by simultaneous application of histone deacetylase inhibitors

(2017) Sheila López-Cobo et al.   OncoImmunology

NKG2D Acts as a Co-Receptor for Natural Killer Cell-Mediated Anti-HIV-1 Antibody-Dependent Cellular Cytotoxicity

(2016) Matthew S. Parsons et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Resistance to cytotoxicity and sustained release of interleukin-6 and interleukin-8 in the presence of decreased interferon-γ after differentiation of glioblastoma by human natural killer cells

(2016) Anna K. Kozlowska et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The influence of NK cell-mediated ADCC: Structure and expression of the CD16 molecule differ among FcγRIIIa-V158F genotypes in healthy Japanese subjects

(2016) Wataru Oboshi et al.   HUMAN IMMUNOLOGY

CD16 is indispensable for antibody-dependent cellular cytotoxicity by human monocytes

(2016) Wei Hseun Yeap et al.   Scientific Reports

Split anergized Natural Killer cells halt inflammation by inducing stem cell differentiation, resistance to NK cell cytotoxicity and prevention of cytokine and chemokine secretion

(2015) Han-Ching Tseng et al.   Oncotarget

Taxanes enhance trastuzumab-mediated ADCC on tumor cells through NKG2D-mediated NK cell recognition

(2015) Martina Di Modica et al.   Oncotarget

Regulation of split anergy in natural killer cells by inhibition of cathepsins C and H and cystatin F

(2015) Spela Magister et al.   Oncotarget

Differential Targeting of Stem Cells and Differentiated Glioblastomas by NK Cells

(2015) Han-Ching Tseng et al.   Journal of Cancer

Augmented IFN-γ and TNF-α Induced by Probiotic Bacteria in NK Cells Mediate Differentiation of Stem-Like Tumors Leading to Inhibition of Tumor Growth and Reduction in Inflammatory Cytokine Release; Regulation by IL-10

(2015) Vickie T. Bui et al.   Frontiers in Immunology

NK cell-mediated antibody-dependent cellular cytotoxicity in cancer immunotherapy

(2015) Wei Wang   Frontiers in Immunology

Identification of an ADAM17 Cleavage Region in Human CD16 (FcγRIII) and the Engineering of a Non-Cleavable Version of the Receptor in NK Cells

(2015) Yawu Jing et al.   PLoS One

FcγRIII (CD16)-mediated ADCC by NK cells is regulated by monocytes and FcγRII (CD32)

(2014) Nupur Bhatnagar et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Macrophage Migration Inhibitory Factor Contributes to the Immune Escape of Ovarian Cancer by Down-Regulating NKG2D

(2014) M. Krockenberger et al.   JOURNAL OF IMMUNOLOGY

A Think Tank of TINK/TANKs: Tumor-Infiltrating/Tumor-Associated Natural Killer Cells in Tumor Progression and Angiogenesis

(2014) Antonino Bruno et al.   JNCI-Journal of the National Cancer Institute

Decreased expression of NKG2D, NKp46, DNAM-1 receptors, and intracellular perforin and STAT-1 effector molecules in NK cells and their dim and bright subsets in metastatic melanoma patients

(2014) Katarina M. Mirjačić Martinović et al.   MELANOMA RESEARCH

Induction of Split Anergy Conditions Natural Killer Cells to Promote Differentiation of Stem Cells through Cell–Cell Contact and Secreted Factors

(2014) Han-Ching Tseng et al.   Frontiers in Immunology

Regulation of Ligands for the NKG2D Activating Receptor

(2013) David H. Raulet et al.   Annual Review of Immunology

Cancer Immunosurveillance and Immunoediting by Natural Killer Cells

(2013) Emilie Gross et al.   CANCER JOURNAL

Targeting Natural Killer Cells to Acute Myeloid Leukemia In Vitro with a CD16 x 33 Bispecific Killer Cell Engager and ADAM17 Inhibition

(2013) A. Wiernik et al.   CLINICAL CANCER RESEARCH

CD3−CD16−CD56bright Immunoregulatory NK Cells are Increased in the Tumor Microenvironment and Inversely Correlate with Advanced Stages in Patients with Papillary Thyroid Cancer

(2013) Foteini Gogali et al.   THYROID

Dual Functions of Natural Killer Cells in Selection and Differentiation of Stem Cells; Role in Regulation of Inflammation and Regeneration of Tissues

(2013) Anahid Jewett et al.   Journal of Cancer

Melanoma Cells Inhibit Natural Killer Cell Function by Modulating the Expression of Activating Receptors and Cytolytic Activity

(2012) G. Pietra et al.   CANCER RESEARCH

Human NK cell lytic granules and regulation of their exocytosis

(2012) Konrad Krzewski et al.   Frontiers in Immunology

Clinical Cancer Therapy by NK Cells via Antibody-Dependent Cell-Mediated Cytotoxicity

(2011) Kory L. Alderson et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Natural Killer Cells in Human Cancer: From Biological Functions to Clinical Applications

(2011) Estrella Mariel Levy et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

NK cell dysfunction with down-regulated CD16 and up-regulated CD56 molecules in patients with esophageal squamous cell carcinoma

(2010) M. Watanabe et al.   DISEASES OF THE ESOPHAGUS

Activating and inhibitory receptors of natural killer cells

(2010) Hollie J Pegram et al.   IMMUNOLOGY AND CELL BIOLOGY

MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells

(2010) Jennifer AA Gubbels et al.   Molecular Cancer

Increased Lysis of Stem Cells but Not Their Differentiated Cells by Natural Killer Cells; De-Differentiation or Reprogramming Activates NK Cells

(2010) Han-Ching Tseng et al.   PLoS One

New views on natural killer cell-based immunotherapy for melanoma treatment

(2010) Shannon Burke et al.   TRENDS IN IMMUNOLOGY

Primary Human Tumor Cells Expressing CD155 Impair Tumor Targeting by Down-Regulating DNAM-1 on NK Cells

(2009) M. Carlsten et al.   JOURNAL OF IMMUNOLOGY

Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity

(2009) M. Balsamo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid and potent induction of cell death and loss of NK cell cytotoxicity against oral tumors by F(ab′)2 fragment of anti-CD16 antibody

(2008) Anahid Jewett et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Natural killer cells and lung transplantation, roles in rejection, infection, and tolerance

(2008) J.E. Fildes et al.   TRANSPLANT IMMUNOLOGY