IgE Activates Monocytes from Cancer Patients to Acquire a Pro-Inflammatory Phenotype

Basophil activation test in cancer patient blood evaluating potential hypersensitivity to an anti‐tumor IgE therapeutic candidate

(2020) Heather J Bax et al.   ALLERGY

Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP

(2020) Yi Zhou et al.   IMMUNITY

Harnessing Therapeutic IgE Antibodies to Re-educate Macrophages against Cancer

(2020) Giulia Pellizzari et al.   TRENDS IN MOLECULAR MEDICINE

AllergoOncology: ultra-low IgE, a potential novel biomarker in cancer—a Position Paper of the European Academy of Allergy and Clinical Immunology (EAACI)

(2020) D. Ferastraoaru et al.   Clinical and Translational Allergy

Immune mediator expression signatures are associated with improved outcome in ovarian carcinoma

(2019) Mano Nakamura et al.   OncoImmunology

Human tumor-associated monocytes/macrophages and their regulation of T cell responses in early-stage lung cancer

(2019) Sunil Singhal et al.   Science Translational Medicine

AllergoOncology: Expression platform development and functional profiling of an anti‐HER2 IgE antibody

(2019) Kristina M. Ilieva et al.   ALLERGY

IgE re-programs alternatively-activated human macrophages towards pro-inflammatory anti-tumoural states

(2019) Giulia Pellizzari et al.   EBioMedicine

IgE deficiency is associated with high rates of new malignancies: Results of a longitudinal cohort study

(2019) Denisa Ferastraoaru et al.   Journal of Allergy and Clinical Immunology-In Practice

Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell–mediated tumor regression

(2019) Anders Etzerodt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Endless Saga of Monocyte Diversity

(2019) Stefania Canè et al.   Frontiers in Immunology

CD206+ tumor-associated macrophages promote proliferation and invasion in oral squamous cell carcinoma via EGF production

(2019) A. S. M. Rafiul Haque et al.   Scientific Reports

An immunologically relevant rodent model demonstrates safety of therapy using a tumour-specific IgE

(2018) Debra H Josephs et al.   ALLERGY

Rapid recruitment of CD14 + monocytes in experimentally induced allergic rhinitis in human subjects

(2016) Ibon Eguíluz-Gracia et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Allergen Valency, Dose, and FcεRI Occupancy Set Thresholds for Secretory Responses to Pen a 1 and Motivate Design of Hypoallergens

(2016) Avanika Mahajan et al.   JOURNAL OF IMMUNOLOGY

ReactomePA: an R/Bioconductor package for reactome pathway analysis and visualization

(2016) Guangchuang Yu et al.   Molecular BioSystems

IgE and mast cells in host defense against parasites and venoms

(2016) Kaori Mukai et al.   Seminars in Immunopathology

IFN  and CCL2 Cooperate to Redirect Tumor-Infiltrating Monocytes to Degrade Fibrosis and Enhance Chemotherapy Efficacy in Pancreatic Carcinoma

(2016) K. B. Long et al.   Cancer Discovery

The role of FcεRI expressed in dendritic cells and monocytes

(2015) Jeoung-Sook Shin et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Diverging biological roles among human monocyte subsets in the context of tuberculosis infection

(2015) Luciana Balboa et al.   CLINICAL SCIENCE

Structure and dynamics of IgE-receptor interactions: FcεRI and CD23/FcεRII

(2015) Brian J. Sutton et al.   IMMUNOLOGICAL REVIEWS

Distinct Contributions of Neutrophils and CCR2+Monocytes to Pulmonary Clearance of Different Klebsiella pneumoniae Strains

(2015) Huizhong Xiong et al.   INFECTION AND IMMUNITY

Ly6ChighMonocytes Control Cerebral Toxoplasmosis

(2015) Aindrila Biswas et al.   JOURNAL OF IMMUNOLOGY

Potential for monocyte recruitment by IgE immunotherapy for cancer in a rat model of tumour metastasis

(2015) Debra H Josephs et al.   LANCET

Functions of dendritic-cell-bound IgE in allergy

(2015) Barbara Platzer et al.   MOLECULAR IMMUNOLOGY

IgE/FcεRI-Mediated Antigen Cross-Presentation by Dendritic Cells Enhances Anti-Tumor Immune Responses

(2015) Barbara Platzer et al.   Cell Reports

Monocyte-Derived Dendritic Cells Are Essential for CD8+ T Cell Activation and Antitumor Responses After Local Immunotherapy

(2015) Sabine Kuhn et al.   Frontiers in Immunology

Rethinking the Role of Immunoglobulin E and Its High-Affinity Receptor: New Insights into Allergy and Beyond

(2014) Barbara Dema et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Dendritic cell-bound IgE functions to restrain allergic inflammation at mucosal sites

(2014) B Platzer et al.   Mucosal Immunology

Signaling Shifts in Allergy Responses

(2014) M. Daeron   SCIENCE

IgE cross-linking critically impairs human monocyte function by blocking phagocytosis

(2013) David M. Pyle et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients

(2012) Balázs Győrffy et al.   ENDOCRINE-RELATED CANCER

The Fyn-STAT5 Pathway: A New Frontier in IgE- and IgG-Mediated Mast Cell Signaling

(2012) Nicholas A. Pullen et al.   Frontiers in Immunology

Recombinant IgE antibodies for passive immunotherapy of solid tumours: from concept towards clinical application

(2011) Sophia N. Karagiannis et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Novel Mechanism for FcϵRI-mediated Signal Transducer and Activator of Transcription 5 (STAT5) Tyrosine Phosphorylation and the Selective Influence of STAT5B over Mast Cell Cytokine Production

(2011) Nicholas A. Pullen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IgE Mediates Killing of Intracellular Toxoplasma gondii by Human Macrophages through CD23-Dependent, Interleukin-10 Sensitive Pathway

(2011) Ioannis Vouldoukis et al.   PLoS One

Il-4 Induces The Expression of The Low Affinity IgE Receptor (CD23) on Human Mast Cells

(2008) E SWARTZ et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY