Spreading of TDP-43 pathology via pyramidal tract induces ALS-like phenotypes in TDP-43 transgenic mice
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Spreading of TDP-43 pathology via pyramidal tract induces ALS-like phenotypes in TDP-43 transgenic mice
Authors
Keywords
-
Journal
Acta Neuropathologica Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-01-19
DOI
10.1186/s40478-020-01112-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The basis of clinicopathological heterogeneity in TDP-43 proteinopathy
- (2019) Ito Kawakami et al. ACTA NEUROPATHOLOGICA
- Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons
- (2018) Adam J. Svahn et al. ACTA NEUROPATHOLOGICA
- Patient-derived frontotemporal lobar degeneration brain extracts induce formation and spreading of TDP-43 pathology in vivo
- (2018) Sílvia Porta et al. Nature Communications
- Amyotrophic lateral sclerosis
- (2017) Michael A van Es et al. LANCET
- Amyotrophic Lateral Sclerosis
- (2017) Robert H. Brown et al. NEW ENGLAND JOURNAL OF MEDICINE
- Thioflavin T as an amyloid dye: fibril quantification, optimal concentration and effect on aggregation
- (2017) Christine Xue et al. Royal Society Open Science
- Formation and spreading of TDP-43 aggregates in cultured neuronal and glial cells demonstrated by time-lapse imaging
- (2017) Tomohiro Ishii et al. PLoS One
- Templated Aggregation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Seeding with TDP-43 Peptide Fibrils
- (2016) Shotaro Shimonaka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Decoding ALS: from genes to mechanism
- (2016) J. Paul Taylor et al. NATURE
- In vitro prion-like behaviour of TDP-43 in ALS
- (2016) Phillip Smethurst et al. NEUROBIOLOGY OF DISEASE
- Diagnostic criteria in amyotrophic lateral sclerosis
- (2016) Nimeshan Geevasinga et al. NEUROLOGY
- TDP-43 is intercellularly transmitted across axon terminals
- (2015) Marisa S. Feiler et al. JOURNAL OF CELL BIOLOGY
- The cell biology of prion-like spread of protein aggregates: mechanisms and implication in neurodegeneration
- (2015) Maddalena Costanzo et al. BIOCHEMICAL JOURNAL
- TDP-43 pathology and neuronal loss in amyotrophic lateral sclerosis spinal cord
- (2014) Johannes Brettschneider et al. ACTA NEUROPATHOLOGICA
- Tissue Triage and Freezing for Models of Skeletal Muscle Disease
- (2014) Hui Meng et al. Jove-Journal of Visualized Experiments
- Stages of pTDP-43 pathology in amyotrophic lateral sclerosis
- (2013) Johannes Brettschneider et al. ANNALS OF NEUROLOGY
- Structural Transformation of the Amyloidogenic Core Region of TDP-43 Protein Initiates Its Aggregation and Cytoplasmic Inclusion
- (2013) Lei-Lei Jiang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Synthetic Tau Fibrils Mediate Transmission of Neurofibrillary Tangles in a Transgenic Mouse Model of Alzheimer's-Like Tauopathy
- (2013) M. Iba et al. JOURNAL OF NEUROSCIENCE
- Self-propagation of pathogenic protein aggregates in neurodegenerative diseases
- (2013) Mathias Jucker et al. NATURE
- Amyotrophic lateral sclerosis—a model of corticofugal axonal spread
- (2013) Heiko Braak et al. Nature Reviews Neurology
- What’s to like about the prion-like hypothesis for the spreading of aggregated α-synuclein in Parkinson disease?
- (2013) Christopher J.R. Dunning et al. Prion
- Prion-like Properties of Pathological TDP-43 Aggregates from Diseased Brains
- (2013) Takashi Nonaka et al. Cell Reports
- Deciphering amyotrophic lateral sclerosis: What phenotype, neuropathology and genetics are telling us about pathogenesis
- (2013) John Ravits et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Trans-cellular Propagation of Tau Aggregation by Fibrillar Species
- (2012) Najla Kfoury et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Can regional spreading of amyotrophic lateral sclerosis motor symptoms be explained by prion-like propagation?
- (2012) Tadashi Kanouchi et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- A Seeding Reaction Recapitulates Intracellular Formation of Sarkosyl-insoluble Transactivation Response Element (TAR) DNA-binding Protein-43 Inclusions
- (2011) Yoshiaki Furukawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amyotrophic lateral sclerosis is a non-amyloid disease in which extensive misfolding of SOD1 is unique to the familial form
- (2010) Aaron Kerman et al. ACTA NEUROPATHOLOGICA
- Mutation-dependent Polymorphism of Cu,Zn-Superoxide Dismutase Aggregates in the Familial Form of Amyotrophic Lateral Sclerosis
- (2010) Yoshiaki Furukawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cell-to-cell transmission of non-prion protein aggregates
- (2010) Seung-Jae Lee et al. Nature Reviews Neurology
- Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy
- (2010) Tetsuaki Arai et al. NEUROPATHOLOGY
- Mice overexpressing corticotropin-releasing factor show brain atrophy and motor dysfunctions
- (2010) Miriam Goebel et al. NEUROSCIENCE LETTERS
- TDP-43 Is Intrinsically Aggregation-prone, and Amyotrophic Lateral Sclerosis-linked Mutations Accelerate Aggregation and Increase Toxicity
- (2009) Brian S. Johnson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Transcellular Spread of Cytosolic Amyloids, Prions, and Prionoids
- (2009) Adriano Aguzzi et al. NEURON
- Enrichment of C-Terminal Fragments in TAR DNA-Binding Protein-43 Cytoplasmic Inclusions in Brain but not in Spinal Cord of Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
- (2008) Lionel M. Igaz et al. AMERICAN JOURNAL OF PATHOLOGY
- Electrodiagnostic criteria for diagnosis of ALS
- (2008) Mamede de Carvalho et al. CLINICAL NEUROPHYSIOLOGY
- An Animal Model of Oral Dysphagia in Amyotrophic Lateral Sclerosis
- (2008) Teresa E. Lever et al. DYSPHAGIA
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started