In situ immunogenic clearance induced by a combination of photodynamic therapy and rho-kinase inhibition sensitizes immune checkpoint blockade response to elicit systemic antitumor immunity against intraocular melanoma and its metastasis

Phase Ib/II trial testing combined radiofrequency ablation and ipilimumab in uveal melanoma (SECIRA-UM)

(2020) Elisa A. Rozeman et al.   MELANOMA RESEARCH

Intrinsic cancer vaccination

(2019) Yoosoo Yang et al.   ADVANCED DRUG DELIVERY REVIEWS

An optimized protocol to determine the engulfment of cancer cells by phagocytes using flow cytometry and fluorescence microscopy

(2019) Gi-Hoon Nam et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Uveal Versus Cutaneous Melanoma; Same Origin, Very Distinct Tumor Types

(2019) Monique K. van der Kooij et al.   Cancers

Degradation of tumour stromal hyaluronan by small extracellular vesicle-PH20 stimulates CD103+ dendritic cells and in combination with PD-L1 blockade boosts anti-tumour immunity

(2019) Yeonsun Hong et al.   Journal of Extracellular Vesicles

Harnessing innate immunity in cancer therapy

(2019) Olivier Demaria et al.   NATURE

Dendritic cell activation by an E. coli-derived monophosphoryl lipid A enhances the efficacy of PD-1 blockade

(2019) Youngmin Jeong et al.   CANCER LETTERS

Nanocage-Therapeutics Prevailing Phagocytosis and Immunogenic Cell Death Awakens Immunity against Cancer

(2018) Eun Jung Lee et al.   ADVANCED MATERIALS

PD-L1 on host cells is essential for PD-L1 blockade–mediated tumor regression

(2018) Haidong Tang et al.   JOURNAL OF CLINICAL INVESTIGATION

PHOTODYNAMIC THERAPY AS PRIMARY TREATMENT FOR SMALL CHOROIDAL MELANOMA

(2018) Elif B. Turkoglu et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

Combined Rho-kinase inhibition and immunogenic cell death triggers and propagates immunity against cancer

(2018) Gi-Hoon Nam et al.   Nature Communications

Three-dimensional Epigenome Statistical Model: Genome-wide Chromatin Looping Prediction

(2018) Ziad Al Bkhetan et al.   Scientific Reports

The hallmarks of successful anticancer immunotherapy

(2018) Lorenzo Galluzzi et al.   Science Translational Medicine

Primary photodynamic therapy with verteporfin for small pigmented posterior pole choroidal melanoma

(2017) I D Fabian et al.   EYE

Melanoma subtypes demonstrate distinct PD-L1 expression profiles

(2017) Genevieve J Kaunitz et al.   LABORATORY INVESTIGATION

Treatment of metastatic uveal melanoma with adoptive transfer of tumour-infiltrating lymphocytes: a single-centre, two-stage, single-arm, phase 2 study

(2017) Smita S Chandran et al.   LANCET ONCOLOGY

A multireferral centre retrospective cohort analysis on the experience in treatment of metastatic uveal melanoma and utilization of sequential liver-directed treatment and immunotherapy

(2017) Malinda Itchins et al.   MELANOMA RESEARCH

Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression

(2017) Angel Garcia-Diaz et al.   Cell Reports

BRACHYTHERAPY ALONE OR WITH NEOADJUVANT PHOTODYNAMIC THERAPY FOR AMELANOTIC CHOROIDAL MELANOMA

(2016) Maria A. Blasi et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

Rational Selection of Syngeneic Preclinical Tumor Models for Immunotherapeutic Drug Discovery

(2016) Suzanne I.S. Mosely et al.   Cancer Immunology Research

Prognosis of uveal melanoma based on race in 8100 patients: The 2015 Doyne Lecture

(2015) C L Shields et al.   EYE

Long-term Results of the UCSF-LBNL Randomized Trial: Charged Particle With Helium Ion Versus Iodine-125 Plaque Therapy for Choroidal and Ciliary Body Melanoma

(2015) Kavita K. Mishra et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Neoantigens in cancer immunotherapy

(2015) T. N. Schumacher et al.   SCIENCE

Long Overall Survival After Dendritic Cell Vaccination in Metastatic Uveal Melanoma Patients

(2014) Kalijn F. Bol et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Phase I/II study of verteporfin photodynamic therapy in locally advanced pancreatic cancer

(2014) M T Huggett et al.   BRITISH JOURNAL OF CANCER

Treatment of posterior uveal melanoma with multi-dose photodynamic therapy

(2014) Paul Rundle   BRITISH JOURNAL OF OPHTHALMOLOGY

Plaque Radiotherapy for Juxtapapillary Choroidal Melanoma

(2014) Mandeep S. Sagoo et al.   JAMA Ophthalmology

SF3B1 Mutations Are Associated with Alternative Splicing in Uveal Melanoma

(2013) S. J. Furney et al.   Cancer Discovery

Immunogenic Cell Death: Can It Be Exploited in PhotoDynamic Therapy for Cancer?

(2012) Elisa Panzarini et al.   Biomed Research International

Synergistic growth inhibition based on small-molecule p53 activation as treatment for intraocular melanoma

(2011) J de Lange et al.   ONCOGENE

Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity

(2010) Mutsuki Amano et al.   Cytoskeleton

Heavy-Atomic Construction of Photosensitizer Nanoparticles for Enhanced Photodynamic Therapy of Cancer

(2010) Chang-Keun Lim et al.   Small

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

(2008) K. Hildner et al.   SCIENCE