Stereospecific and stereoconvergent nucleophilic substitution reactions at tertiary carbon centers

Nucleophilic Substitution at Quaternary Carbon Stereocenters

(2020) Veeranjaneyulu Lanke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An enantioconvergent halogenophilic nucleophilic substitution (SN2X) reaction

(2019) Xin Zhang et al.   SCIENCE

Coordination-Induced Stereocontrol over Carbocations: Asymmetric Reductive Deoxygenation of Racemic Tertiary Alcohols

(2019) Mayuko Isomura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diastereo- and Enantioselective Copper-Catalyzed Decarboxylative Ring-Opening [3 + 2] Annulation of Tertiary Propargylic Carbamates through Regioselective α-Attack of γ-Butenolides

(2019) You-Wei Xu et al.   ORGANIC LETTERS

Catalysis of Organic Reactions through Halogen Bonding

(2019) Revannath L. Sutar et al.   ACS Catalysis

Intramolecular substitutions of secondary and tertiary alcohols with chirality transfer by an iron(III) catalyst

(2019) Rahul A. Watile et al.   Nature Communications

Catalysis with Pnictogen, Chalcogen, and Halogen Bonds

(2018) Sebastian Benz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nucleophilic Substitution (SN 2): Dependence on Nucleophile, Leaving Group, Central Atom, Substituents, and Solvent

(2018) Trevor A. Hamlin et al.   CHEMPHYSCHEM

Formal enantioconvergent substitution of alkyl halides via catalytic asymmetric photoredox radical coupling

(2018) Jiangtao Li et al.   Nature Communications

Sigma-Hole Interactions in Anion Recognition

(2018) Jason Y.C. Lim et al.   Chem

Quaternary stereocentres via an enantioconvergent catalytic SN1 reaction

(2018) Alison E. Wendlandt et al.   NATURE

Catalytic Stereoselective SN 1-Type Reactions Promoted by Chiral Phosphoric Acids as Brønsted Acid Catalysts

(2018) Andrea Gualandi et al.   Asian Journal of Organic Chemistry

Stereoinversion of Unactivated Alcohols by Tethered Sulfonamides

(2018) Paul T. Marcyk et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic enantioconvergent coupling of secondary and tertiary electrophiles with olefins

(2018) Zhaobin Wang et al.   NATURE

Enantioselective Synthesis of Chiral α-Azido and α-Aryloxy Quaternary Stereogenic Centers via the Phase-Transfer-Catalyzed α-Alkylation of α-Bromomalonates, Followed by SN2 Substitution

(2017) Doyoung Kim et al.   JOURNAL OF ORGANIC CHEMISTRY

Chiral Brønsted Acid Catalyzed Enantioselective aza-Friedel–Crafts Reaction of Cyclic α-Diaryl N-Acyl Imines with Indoles

(2017) Danijel Glavač et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Hydrophosphonylation of in Situ Generated N-Acyl Ketimines Catalyzed by BINOL-Derived Phosphoric Acid

(2017) Arun Suneja et al.   ORGANIC LETTERS

Stereoselective SN1-Type Reaction of Enols and Enolates

(2017) Andrea Gualandi et al.   SYNTHESIS-STUTTGART

Chiral phosphoric acid catalyzed enantioselective addition of thiols to in situ generated ketimines: Synthesis of N , S -ketals

(2017) Rajshekhar A. Unhale et al.   TETRAHEDRON LETTERS

Enantioselective decarboxylative chlorination of β-ketocarboxylic acids

(2017) Kazutaka Shibatomi et al.   Nature Communications

Transition-Metal Catalysis of Nucleophilic Substitution Reactions: A Radical Alternative to SN1 and SN2 Processes

(2017) Gregory C. Fu   ACS Central Science

Stereospecific and stereoconvergent cross-couplings between alkyl electrophiles

(2017) Erika L. Lucas et al.   Nature Reviews Chemistry

Chiral Imidodiphosphoric Acids-Catalyzed Friedel-Crafts Reactions of Indoles/Pyrroles with 3-Hydroxy-indolyloxindoles: Enantioselective Synthesis of 3,3-Diaryloxindoles

(2016) Ming-Hua Zhuo et al.   ADVANCED SYNTHESIS & CATALYSIS

Chiral Brønsted acid-catalysed enantioselective synthesis of isoindolinone-derived N(acyl),S-acetals

(2016) Josipa Suć et al.   CHEMICAL COMMUNICATIONS

The Halogen Bond

(2016) Gabriella Cavallo et al.   CHEMICAL REVIEWS

Activation of the SN2 Reaction by Adjacent π Systems: The Critical Role of Electrostatic Interactions and of Dissociative Character

(2016) Raphaël Robiette et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric copper-catalyzed C-N cross-couplings induced by visible light

(2016) Q. M. Kainz et al.   SCIENCE

Enantioselective Copper(I)-Catalyzed Alkynylation of Oxocarbenium Ions to Set Diaryl Tetrasubstituted Stereocenters

(2015) Srimoyee Dasgupta et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective α-Alkylation of Aldehydes by Photoredox Organocatalysis: Rapid Access to Pharmacophore Fragments from β-Cyanoaldehydes

(2015) Eric R. Welin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric 1,6-Conjugate Addition ofpara-Quinone Methides: Formation of All-Carbon Quaternary Stereocenters

(2015) Zhaobin Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective and Enantiospecific Transition-Metal-Catalyzed Cross-Coupling Reactions of Organometallic Reagents To Construct C–C Bonds

(2015) Alan H. Cherney et al.   CHEMICAL REVIEWS

Enantioselective synthesis of tertiary α-chloro esters by non-covalent catalysis

(2015) Richard Y. Liu et al.   TETRAHEDRON LETTERS

Friedel–Crafts alkylation of heteroarenes and arenes with indolyl alcohols for construction of 3,3-disubstituted oxindoles

(2015) Xiaoxiao Wang et al.   RSC Advances

Enantioselective Formation of All-Carbon Quaternary Stereocenters from Indoles and Tertiary Alcohols Bearing A Directing Group

(2014) Wanxiang Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic enantioselective and (Z)-selective allylation of 3-indolylmethanol via hydrogen-bond activation

(2014) Yan Liu et al.   CHEMICAL COMMUNICATIONS

Highly diastereo- and enantioselective construction of a spiro[cyclopenta[b]indole-1,3′-oxindole] scaffold via catalytic asymmetric formal [3+2] cycloadditions

(2014) Wei Tan et al.   CHEMICAL COMMUNICATIONS

Brønsted Acid Catalyzed Asymmetric SN2-Type O-Alkylations

(2013) Ilija Čorić et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tertiary Alcohols as Substrates for SN2-Like Stereoinversion

(2013) Andreas F. B. Räder et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Organocatalytic Construction of Hexahydropyrroloindole by Means of α-Alkylation of Aldehydes Leading to the Total Synthesis of (+)-Gliocladin C

(2013) Jin Song et al.   CHEMISTRY-A EUROPEAN JOURNAL

Stereoinversion of tertiary alcohols to tertiary-alkyl isonitriles and amines

(2013) Sergey V. Pronin et al.   NATURE

Chiral phosphoric acid catalyzed asymmetric hydrogenolysis of racemic 3-aryl-3-hydroxyisoindolin-1-ones

(2013) Jian-Qing Zhou et al.   TETRAHEDRON LETTERS

The Direct Asymmetric α Alkylation of Ketones by Brønsted Acid Catalysis

(2012) Liu Song et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Brønsted Acid Catalyzed Enantioselective α-Amidoalkylation in the Synthesis of Isoindoloisoquinolines

(2012) Eider Aranzamendi et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly Enantioselective Chlorination of β-Keto Esters and Subsequent SN2 Displacement of Tertiary Chlorides: A Flexible Method for the Construction of Quaternary Stereogenic Centers

(2012) Kazutaka Shibatomi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nucleophilic substitution at the halogen atom (halogenophilic reactions)

(2012) Petr K Sazonov et al.   RUSSIAN CHEMICAL REVIEWS

Asymmetric hydrogenolysis of racemic tertiary alcohols, 3-substituted 3-hydroxyisoindolin-1-ones

(2011) Mu-Wang Chen et al.   CHEMICAL COMMUNICATIONS

Organocatalyzed Enantioselective Synthesis of Quaternary Carbon-Containing Isoindolin-1-ones

(2011) Xiaolei Yu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A cascade process for the synthesis of gem-difluoromethylene compounds

(2011) Zixian Chen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Chiral phosphoric acid-catalysed Friedel–Crafts alkylation reaction of indoles with racemic spiro indolin-3-ones

(2011) Qin Yin et al.   Chemical Science

Is Halogen Bonding the Basis for Iodothyronine Deiodinase Activity?

(2010) Craig A. Bayse et al.   INORGANIC CHEMISTRY

On the role of halogen bond in the halophilic reaction: A theoretical study

(2010) Yu Zhang   JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM

Mitsunobu Approach to the Synthesis of Optically Active α,α-Disubstituted Amino Acids

(2009) Jonathan E. Green et al.   ORGANIC LETTERS

Asymmetric Brønsted Acid Catalyzed Nucleophilic Addition to in situ Generated Chiral N-Acyliminium Ions

(2009) Magnus Rueping et al.   SYNLETT

Regio- and Enantioselective Catalytic Cyclization of Pyrroles ontoN-Acyliminium Ions

(2008) Izzat T. Raheem et al.   ORGANIC LETTERS

Merging Photoredox Catalysis with Organocatalysis: The Direct Asymmetric Alkylation of Aldehydes

(2008) D. A. Nicewicz et al.   SCIENCE

Asymmetric Brønsted Acid Catalysis: Enantioselective Nucleophilic Substitutions and 1,4-Additions

(2007) Magnus Rueping et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION