The role of bioactive lipids in attenuating the neuroinflammatory cascade in traumatic brain injury

Plasma Lipidomic Analyses in Cohorts With mTBI and/or PTSD Reveal Lipids Differentially Associated With Diagnosis and APOE ε4 Carrier Status

(2020) Claire J. C. Huguenard et al.   Frontiers in Physiology

Microglia: Agents of the CNS Pro-Inflammatory Response

(2020) José A. Rodríguez-Gómez et al.   Cells

Mitochondrial dysfunctioning and neuroinflammation: Recent highlights on the possible mechanisms involved in Traumatic Brain Injury

(2019) Deepak Kumar Sahel et al.   NEUROSCIENCE LETTERS

Pro- and anti-inflammatory biomarkers and traumatic brain injury outcomes: A review

(2018) Tamar Rodney et al.   CYTOKINE

OXIDIZED PHOSPHOLIPID SIGNALING IN TRAUMATIC BRAIN INJURY

(2018) Tamil S. Anthonymuthu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Discovery of Lipidome Alterations Following Traumatic Brain Injury via High-Resolution Metabolomics

(2018) Scott R. Hogan et al.   JOURNAL OF PROTEOME RESEARCH

Resolvin D1 Halts Remote Neuroinflammation and Improves Functional Recovery after Focal Brain Damage Via ALX/FPR2 Receptor-Regulated MicroRNAs

(2018) Elisa Bisicchia et al.   MOLECULAR NEUROBIOLOGY

Mannitol and Hypertonic Saline Reduce Swelling and Modulate Inflammatory Markers in a Rat Model of Intracerebral Hemorrhage

(2018) David L. Schreibman et al.   Neurocritical Care

Bioactive Lipids and Chronic Inflammation: Managing the Fire Within

(2018) Valerio Chiurchiù et al.   Frontiers in Immunology

Disruption in Brain Phospholipid Content in a Humanized Tau Transgenic Model Following Repetitive Mild Traumatic Brain Injury

(2018) Joseph O. Ojo et al.   Frontiers in Neuroscience

Phase II Clinical Trial of Atorvastatin in Mild Traumatic Brain Injury

(2017) Claudia S. Robertson et al.   JOURNAL OF NEUROTRAUMA

Elovanoids are a novel class of homeostatic lipid mediators that protect neural cell integrity upon injury

(2017) Surjyadipta Bhattacharjee et al.   Science Advances

Recent Advances in Pathophysiology of Traumatic Brain Injury

(2017) Parmeet Kaur et al.   Current Neuropharmacology

Targeting coagulation factor XII as a novel therapeutic option in brain trauma

(2016) Sarah Hopp et al.   ANNALS OF NEUROLOGY

Mitochondrial division inhibitor 1 (Mdivi-1) offers neuroprotection through diminishing cell death and improving functional outcome in a mouse model of traumatic brain injury

(2016) Qiong Wu et al.   BRAIN RESEARCH

Treatment of traumatic brain injury with anti-inflammatory drugs

(2016) Peter J. Bergold   EXPERIMENTAL NEUROLOGY

Microglia in the TBI brain: The good, the bad, and the dysregulated

(2016) David J. Loane et al.   EXPERIMENTAL NEUROLOGY

Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation

(2016) Kristina N. Ekdahl et al.   IMMUNOLOGICAL REVIEWS

Plasma Lipidomic Profiling in a Military Population of Mild Traumatic Brain Injury and Post-Traumatic Stress Disorder with Apolipoprotein E ɛ4–Dependent Effect

(2016) Tanja Emmerich et al.   JOURNAL OF NEUROTRAUMA

Functions and mechanisms of microglia/macrophages in neuroinflammation and neurogenesis after stroke

(2016) Xiao-Yi Xiong et al.   PROGRESS IN NEUROBIOLOGY

Lipoxin A4 Reduces Inflammation Through Formyl Peptide Receptor 2/p38 MAPK Signaling Pathway in Subarachnoid Hemorrhage Rats

(2016) Zongduo Guo et al.   STROKE

Traumatic Brain Injury and Mitochondrial Dysfunction

(2015) John B. Hiebert et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Resolvins AT-D1 and E1 differentially impact functional outcome, post-traumatic sleep, and microglial activation following diffuse brain injury in the mouse

(2015) Jordan L. Harrison et al.   BRAIN BEHAVIOR AND IMMUNITY

Immunometabolism governs dendritic cell and macrophage function

(2015) Luke A.J. O’Neill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lipopolysaccharide-induced blood-brain barrier disruption: roles of cyclooxygenase, oxidative stress, neuroinflammation, and elements of the neurovascular unit

(2015) William A. Banks et al.   Journal of Neuroinflammation

Clinical evidence of inflammation driving secondary brain injury

(2015) Holly E. Hinson et al.   Journal of Trauma and Acute Care Surgery

Traumatic Brain Injury and NADPH Oxidase: A Deep Relationship

(2015) Cristina Angeloni et al.   Oxidative Medicine and Cellular Longevity

The Role of Lipids Mediators in Inflammation and Resolution

(2015) Alexandre de Paula Rogerio et al.   Biomed Research International

Clinical evidence of inflammation driving secondary brain injury

(2015) Holly E. Hinson et al.   Journal of Trauma and Acute Care Surgery

Hippocampal Neuro-Networks and Dendritic Spine Perturbations in Epileptogenesis Are Attenuated by Neuroprotectin D1

(2015) Alberto E. Musto et al.   PLoS One

Targeted Lipid Profiling Discovers Plasma Biomarkers of Acute Brain Injury

(2015) Sunil A. Sheth et al.   PLoS One

Lipidomic analyses identify injury-specific phospholipid changes 3 mo after traumatic brain injury

(2014) Laila Abdullah et al.   FASEB JOURNAL

Melatonin stimulates antioxidant enzymes and reduces oxidative stress in experimental traumatic brain injury: the Nrf2–ARE signaling pathway as a potential mechanism

(2014) Ke Ding et al.   FREE RADICAL BIOLOGY AND MEDICINE

Melatonin reduced microglial activation and alleviated neuroinflammation induced neuron degeneration in experimental traumatic brain injury: Possible involvement of mTOR pathway

(2014) Ke Ding et al.   NEUROCHEMISTRY INTERNATIONAL

Dementia Risk After Traumatic Brain Injury vs Nonbrain Trauma

(2014) Raquel C. Gardner et al.   JAMA Neurology

Aspirin-Triggered Lipoxin A4 Stimulates Alternative Activation of Microglia and Reduces Alzheimer Disease–Like Pathology in Mice

(2013) Rodrigo Medeiros et al.   AMERICAN JOURNAL OF PATHOLOGY

Lipoxin A4 attenuates brain damage and downregulates the production of pro-inflammatory cytokines and phosphorylated mitogen-activated protein kinases in a mouse model of traumatic brain injury

(2013) Cheng-Liang Luo et al.   BRAIN RESEARCH

Coagulopathy after traumatic brain injury: incidence, pathogenesis, and treatment options

(2013) Marc Maegele   TRANSFUSION

Metabolic Crisis in Severely Head-Injured Patients: Is Ischemia Just the Tip of the Iceberg?

(2013) Emilie Carre et al.   Frontiers in Neurology

Therapeutic use of omega-3 fatty acids in severe head trauma

(2012) Michael Lewis et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Results of a phase II placebo-controlled randomized trial of minocycline in acute spinal cord injury

(2012) Steven Casha et al.   BRAIN

Novel aspirin-triggered neuroprotectin D1 attenuates cerebral ischemic injury after experimental stroke

(2012) Nicolas G. Bazan et al.   EXPERIMENTAL NEUROLOGY

The immunology of traumatic brain injury: a prime target for Alzheimer’s disease prevention

(2012) Brian Giunta et al.   Journal of Neuroinflammation

Exposure to Lipopolysaccharide and/or Unconjugated Bilirubin Impair the Integrity and Function of Brain Microvascular Endothelial Cells

(2012) Filipa L. Cardoso et al.   PLoS One

Acute Minocycline Treatment Mitigates the Symptoms of Mild Blast-Induced Traumatic Brain Injury

(2012) Erzsebet Kovesdi et al.   Frontiers in Neurology

A Lipoxin A4 Analog Ameliorates Blood–Brain Barrier Dysfunction and Reduces MMP-9 Expression in a Rat Model of Focal Cerebral Ischemia–Reperfusion Injury

(2011) Yan Wu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Role of Bcl-2 family proteins and caspases in the regulation of apoptosis

(2011) Mohammad Shamsul Ola et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Oral fish oil restores striatal dopamine release after traumatic brain injury

(2011) Samuel S. Shin et al.   NEUROSCIENCE LETTERS

Specialized pro-resolving lipid mediators in the inflammatory response: An update

(2010) Gerard Bannenberg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation

(2010) J.-C. Rodriguez-Prados et al.   JOURNAL OF IMMUNOLOGY

Omega-3 fatty acid supplementation and reduction of traumatic axonal injury in a rodent head injury model

(2010) James D. Mills et al.   JOURNAL OF NEUROSURGERY

Docosahexaenoic Acid Reduces Traumatic Axonal Injury in a Rodent Head Injury Model

(2010) Julian E. Bailes et al.   JOURNAL OF NEUROTRAUMA

Hypertonic saline ameliorates cerebral edema through downregulation of aquaporin-4 expression in the astrocytes

(2010) H.K. Zeng et al.   NEUROSCIENCE

Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies

(2010) David J. Loane et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Minocycline effects on cerebral edema: Relations with inflammatory and oxidative stress markers following traumatic brain injury in mice

(2009) Shadi Homsi et al.   BRAIN RESEARCH

Lipopolysaccharide-Induced Apoptosis in Transformed Bovine Brain Endothelial Cells and Human Dermal Microvessel Endothelial Cells: The Role of JNK

(2009) H. Karahashi et al.   JOURNAL OF IMMUNOLOGY

The Nitrone Free Radical Scavenger NXY-059 Is Neuroprotective when Administered after Traumatic Brain Injury in the Rat

(2009) Fredrik Clausen et al.   JOURNAL OF NEUROTRAUMA

Temporal Profile of Thrombogenesis in the Cerebral Microcirculation after Traumatic Brain Injury in Mice

(2009) Susanne M. Schwarzmaier et al.   JOURNAL OF NEUROTRAUMA

VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown

(2009) Azeb Tadesse Argaw et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid Mediators in Health and Disease: Enzymes and Receptors as Therapeutic Targets for the Regulation of Immunity and Inflammation

(2008) Takao Shimizu   Annual Review of Pharmacology and Toxicology

Neuroprotective Effects of Tempol, a Catalytic Scavenger of Peroxynitrite-Derived Free Radicals, in a Mouse Traumatic Brain Injury Model

(2008) Ying Deng-Bryant et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Surviving a Mine Explosion

(2008) Lawrence Roberts et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS