Inhibition of the P53 / P21 Pathway Attenuates the Effects of Senescent Nucleus Pulposus Cell‐Derived Exosomes on the Senescence of Nucleus Pulposus Cells

Melatonin‐stimulated exosomes enhance the regenerative potential of chronic kidney disease‐derived mesenchymal stem/stromal cells via cellular prion proteins

(2020) Yeo Min Yoon et al.   JOURNAL OF PINEAL RESEARCH

p16 deficiency attenuates intervertebral disc degeneration by adjusting oxidative stress and nucleus pulposus cell cycle

(2020) Hui Che et al.   eLife

Biology of extracellular vesicles secreted from senescent cells as senescence‐associated secretory phenotype factors

(2020) Tomoka Misawa et al.   Geriatrics & Gerontology International

Premature senescence in human melanocytes after exposure to solar UVR: An exosome and UV‐miRNA connection

(2020) Jingfeng Sha et al.   Pigment Cell & Melanoma Research

Correction: Primary tumor-derived exosomes facilitate metastasis by regulating adhesion of circulating tumor cells via SMAD3 in liver cancer

(2019) Qihan Fu et al.   ONCOGENE

Inhibition of the Notch1 Pathway Promotes the Effects of Nucleus Pulposus Cell-Derived Exosomes on the Differentiation of Mesenchymal Stem Cells into Nucleus Pulposus-Like Cells in Rats

(2019) Wei-ren Lan et al.   Stem Cells International

Sirtuin 2 expression suppresses oxidative stress and senescence of nucleus pulposus cells through inhibition of the p53/p21 pathway

(2019) Maojie Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3

(2019) Michela Borghesan et al.   Cell Reports

hucMSC Exosome-Derived GPX1 Is Required for the Recovery of Hepatic Oxidant Injury

(2017) Yongmin Yan et al.   MOLECULAR THERAPY

MSC exosome as a cell-free MSC therapy for cartilage regeneration: Implications for osteoarthritis treatment

(2017) Wei Seong Toh et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2

(2017) Masaki Takasugi et al.   Nature Communications

Exosomes as potential alternatives to stem cell therapy for intervertebral disc degeneration: in-vitro study on exosomes in interaction of nucleus pulposus cells and bone marrow mesenchymal stem cells

(2017) Kang Lu et al.   Stem Cell Research & Therapy

PREPARE: Pre-surgery physiotherapy for patients with degenerative lumbar spine disorder: a randomized controlled trial protocol

(2016) Yvonne Lindbäck et al.   BMC MUSCULOSKELETAL DISORDERS

Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways

(2016) Chencheng Feng et al.   CELL CYCLE

Aging and age related stresses: a senescence mechanism of intervertebral disc degeneration

(2016) F. Wang et al.   OSTEOARTHRITIS AND CARTILAGE

Osteoclast-derived microRNA-containing exosomes selectively inhibit osteoblast activity

(2016) Weijia Sun et al.   Cell Discovery

The role of senescent cells in ageing

(2014) Jan M. van Deursen   NATURE

A role for TNFα in intervertebral disc degeneration: A non-recoverable catabolic shift

(2013) D. Purmessur et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

In vitro lifespan and senescence mechanisms of human nucleus pulposus chondrocytes

(2013) Seo-Won Jeong et al.   Spine Journal

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Theo Vos et al.   LANCET

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY