Inhibition of the Notch1 Pathway Promotes the Effects of Nucleus Pulposus Cell-Derived Exosomes on the Differentiation of Mesenchymal Stem Cells into Nucleus Pulposus-Like Cells in Rats

Notch1 regulates endothelial apoptosis via ERK pathway in chronic obstructive pulmonary disease

(2018) Dandan Zong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mesenchymal stromal cell-derived extracellular vesicles: regenerative and immunomodulatory effects and potential applications in sepsis

(2018) Guoping Zheng et al.   CELL AND TISSUE RESEARCH

Transplantation of allogenic nucleus pulposus cells attenuates intervertebral disc degeneration by inhibiting apoptosis and increasing migration

(2018) Weiheng Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Exosomes derived from human umbilical cord mesenchymal stem cells improve myocardial repair via upregulation of Smad7

(2018) Xin‑Long Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Notch-1-PTEN-ERK1/2 signaling axis promotes HER2+ breast cancer cell proliferation and stem cell survival

(2018) Andrew Baker et al.   ONCOGENE

Primary tumor-derived exosomes facilitate metastasis by regulating adhesion of circulating tumor cells via SMAD3 in liver cancer

(2018) Qihan Fu et al.   ONCOGENE

Treatment of lumbar degenerative disc disease-associated radicular pain with culture-expanded autologous mesenchymal stem cells: a pilot study on safety and efficacy

(2017) Christopher Centeno et al.   Journal of Translational Medicine

hucMSC Exosome-Derived GPX1 Is Required for the Recovery of Hepatic Oxidant Injury

(2017) Yongmin Yan et al.   MOLECULAR THERAPY

MSC exosome as a cell-free MSC therapy for cartilage regeneration: Implications for osteoarthritis treatment

(2017) Wei Seong Toh et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Oleanolic Acid Enhances Mesenchymal Stromal Cell Osteogenic Potential by Inhibition of Notch Signaling

(2017) Bing Shu et al.   Scientific Reports

Basic fibroblast growth factor reduces scar by inhibiting the differentiation of epidermal stem cells to myofibroblasts via the Notch1/Jagged1 pathway

(2017) Peng Wang et al.   Stem Cell Research & Therapy

Exosomes as potential alternatives to stem cell therapy for intervertebral disc degeneration: in-vitro study on exosomes in interaction of nucleus pulposus cells and bone marrow mesenchymal stem cells

(2017) Kang Lu et al.   Stem Cell Research & Therapy

Modulation of the gene expression of annulus fibrosus-derived stem cells using poly(ether carbonate urethane)urea scaffolds of tunable elasticity

(2016) Caihong Zhu et al.   Acta Biomaterialia

Thermally triggered injectable hydrogel, which induces mesenchymal stem cell differentiation to nucleus pulposus cells: Potential for regeneration of the intervertebral disc

(2016) A.A. Thorpe et al.   Acta Biomaterialia

Autogenous Mesenchymal Stem Cells from the Vertebral Body Enhance Intervertebral Disc Regeneration via Paracrine Interaction: An in Vitro Pilot Study

(2016) Eun-Kyung Shim et al.   CELL TRANSPLANTATION

MIF Plays a Key Role in Regulating Tissue-Specific Chondro-Osteogenic Differentiation Fate of Human Cartilage Endplate Stem Cells under Hypoxia

(2016) Yuan Yao et al.   Stem Cell Reports

Osteoclast-derived microRNA-containing exosomes selectively inhibit osteoblast activity

(2016) Weijia Sun et al.   Cell Discovery

Exosomes: Vehicles of Intercellular Signaling, Biomarkers, and Vectors of Cell Therapy

(2015) Stella Kourembanas   Annual Review of Physiology

Inhibition of Notch Signaling Promotes the Adipogenic Differentiation of Mesenchymal Stem Cells Through Autophagy Activation and PTEN-PI3K/AKT/mTOR Pathway

(2015) Bao-quan Song et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Effect of lentivirus-mediated survivin transfection on the morphology and apoptosis of nucleus pulposus cells derived from degenerative human disc in vitro

(2015) XUEXIAO MA et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Notch inhibits chondrogenic differentiation of mesenchymal progenitor cells by targeting Twist1

(2015) Ye Tian et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Growth differentiation factor 6 and transforming growth factor-beta differentially mediate mesenchymal stem cell differentiation, composition, and micromechanical properties of nucleus pulposus constructs

(2014) Louise E Clarke et al.   ARTHRITIS RESEARCH & THERAPY

Optimization of culture of mesenchymal stem cells: a comparison of conventional plate and microcarrier cultures

(2012) J. Chang et al.   CELL PROLIFERATION

Hypoxia inhibits the differentiation of mesenchymal stem cells into osteoblasts by activation of Notch signaling

(2012) Ningru Xu et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Theo Vos et al.   LANCET

The Effect of Two- and Three-Dimensional Cell Culture on the Chondrogenic Potential of Human Adipose-Derived Mesenchymal Stem Cells after Subcutaneous Transplantation with an Injectable Hydrogel

(2011) Christophe Merceron et al.   CELL TRANSPLANTATION

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY

Adipose-Derived Stem Cell Therapy for Intervertebral Disc Regeneration: An In Vitro Reconstructed Tissue in Alginate Capsules

(2008) Paolo Gaetani et al.   TISSUE ENGINEERING PART A