A weighted and integrated drug-target interactome: drug repurposing for schizophrenia as a use case

Computational Drug Repositioning: From Data to Therapeutics

(2013) M R Hurle et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Sibutramine in the treatment of antipsychotic-induced weight gain

(2013) Falko Biedermann et al.   INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY

Increasing the clozapine: Norclozapine ratio with co-administration of fluvoxamine to enhance efficacy and minimize side effects of clozapine therapy

(2013) Nancy Légaré et al.   MEDICAL HYPOTHESES

DGIdb: mining the druggable genome

(2013) Malachi Griffith et al.   NATURE METHODS

A Drug Repositioning Approach Identifies Tricyclic Antidepressants as Inhibitors of Small Cell Lung Cancer and Other Neuroendocrine Tumors

(2013) N. S. Jahchan et al.   Cancer Discovery

Antipsychotic agents screened as human carbonic anhydrase I and II inhibitors

(2013) Mahmut Erzengin et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Pharmacogenomics Knowledge for Personalized Medicine

(2012) M Whirl-Carrillo et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A Randomized, Double-Blind, Placebo-Controlled Trial of Fluvoxamine in Patients With Schizophrenia

(2012) Tomihisa Niitsu et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Use of genome-wide association studies for drug repositioning

(2012) Philippe Sanseau et al.   NATURE BIOTECHNOLOGY

Reducing antipsychotic-induced weight gain in schizophrenia: a double-blind placebo-controlled study of reboxetine–betahistine combination

(2012) Michael Poyurovsky et al.   PSYCHOPHARMACOLOGY

Drug discovery in the age of systems biology: the rise of computational approaches for data integration

(2011) Murat Iskar et al.   CURRENT OPINION IN BIOTECHNOLOGY

Systematic Drug Repositioning Based on Clinical Side-Effects

(2011) Lun Yang et al.   PLoS One

Polypharmacy in schizophrenia

(2010) Mathias Zink et al.   CURRENT OPINION IN PSYCHIATRY

Systems Pharmacology

(2010) Aislyn D. W. Boran et al.   MOUNT SINAI JOURNAL OF MEDICINE

PROMISCUOUS: a database for network-based drug-repositioning

(2010) J. von Eichborn et al.   NUCLEIC ACIDS RESEARCH

Entrez Gene: gene-centered information at NCBI

(2010) D. Maglott et al.   NUCLEIC ACIDS RESEARCH

A multi-dimensional evidence-based candidate gene prioritization approach for complex diseases–schizophrenia as a case

(2009) Jingchun Sun et al.   BIOINFORMATICS

Network analyses in systems pharmacology

(2009) S. I. Berger et al.   BIOINFORMATICS

SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions

(2009) Saskia Preissner et al.   NUCLEIC ACIDS RESEARCH

PubChem: a public information system for analyzing bioactivities of small molecules

(2009) Y. Wang et al.   NUCLEIC ACIDS RESEARCH

PDTD: a web-accessible protein database for drug target identification

(2008) Zhenting Gao et al.   BMC BIOINFORMATICS

Genomic-scale prioritization of drug targets: the TDR Targets database

(2008) Fernán Agüero et al.   NATURE REVIEWS DRUG DISCOVERY