A Glance at the Use of Glucocorticoids in Rare Inflammatory and Autoimmune Diseases: Still an Indispensable Pharmacological Tool?

Glucocorticoid-Induced Leucine Zipper as a Druggable Target in Inflammatory Bowel Diseases

(2020) Simona Ronchetti et al.   INFLAMMATORY BOWEL DISEASES

Hemophagocytic lymphohistiocytosis: An update on pathogenesis, diagnosis, and therapy

(2020) Georgia Griffin et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Prolonged treatment with the synthetic glucocorticoid methylprednisolone affects adrenal steroidogenic function and response to inflammatory stress in the rat

(2020) Francesca Spiga et al.   BRAIN BEHAVIOR AND IMMUNITY

Extra-adrenal glucocorticoid biosynthesis: implications for autoimmune and inflammatory disorders

(2020) Radomir M. Slominski et al.   GENES AND IMMUNITY

Immunosuppressive and glucocorticoid therapy for the treatment of ANCA-asssociated vasculitis

(2020) Irmgard Neumann   RHEUMATOLOGY

Insulin Autoimmune Syndrome (Hirata Disease): A Comprehensive Review Fifty Years After Its First Description

(2020) Daniele Cappellani et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

IVIG in childhood primary angiitis of the central nervous system: A case report

(2020) Hiroya Nishida et al.   BRAIN & DEVELOPMENT

The great imitator with no diagnostic test: pyoderma gangrenosum

(2020) Teresa Alonso‐León et al.   International Wound Journal

Are the steroids a blanket solution for COVID‐19? A systematic review and meta‐analysis

(2020) Soumya Sarkar et al.   JOURNAL OF MEDICAL VIROLOGY

Glucocorticoid-Induced Leucine Zipper: A Novel Anti-inflammatory Molecule

(2019) Oxana Bereshchenko et al.   Frontiers in Pharmacology

Consensus-based recommendations for the management of juvenile localised scleroderma

(2019) Francesco Zulian et al.   ANNALS OF THE RHEUMATIC DISEASES

New causes of hypophysitis

(2019) Kevin C.J. Yuen et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Orphan drug development: the increasing role of clinical pharmacology

(2019) Mariam A. Ahmed et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile

(2019) Karen Dendoncker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pemphigus: Current and Future Therapeutic Strategies

(2019) Dario Didona et al.   Frontiers in Immunology

A General Introduction to Glucocorticoid Biology

(2019) Steven Timmermans et al.   Frontiers in Immunology

Strategies for treatment of childhood primary angiitis of the central nervous system

(2019) Jocelyne Beelen et al.   Neurology-Neuroimmunology & Neuroinflammation

Recent Advances in Pharmacological Treatments of Adult Dermatomyositis

(2019) Kristen L. Chen et al.   Current Rheumatology Reports

Glucocorticoids and Glucocorticoid-Induced-Leucine-Zipper (GILZ) in Psoriasis

(2019) Lisa M. Sevilla et al.   Frontiers in Immunology

Assessment of TNF-α inhibitors in airway involvement of relapsing polychondritis

(2019) Josette Biya et al.   MEDICINE

Synthetic glucocorticoid-induced leucine zipper peptide inhibits lipopolysaccharide-induced ocular inflammation in rats

(2019) Yue Guo et al.   OPHTHALMIC RESEARCH

Overview of Juvenile localized scleroderma and its management

(2019) Suzanne C. Li et al.   World Journal of Pediatrics

IgG4-related disease: a clinical perspective

(2019) Federica Maritati et al.   RHEUMATOLOGY

Efficacy and safety of biologics in relapsing polychondritis: a French national multicentre study

(2018) Guillaume Moulis et al.   ANNALS OF THE RHEUMATIC DISEASES

Therapeutic Mechanisms of Glucocorticoids

(2018) Jolien Vandewalle et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Pathogenetic and Clinical Aspects of Anti-Neutrophil Cytoplasmic Autoantibody-Associated Vasculitides

(2018) Peter Lamprecht et al.   Frontiers in Immunology

Defining the role of glucocorticoids in inflammation

(2018) Simona Ronchetti et al.   CLINICAL SCIENCE

Targeted Therapies for Autoimmune Bullous Diseases: Current Status

(2018) Kyle T. Amber et al.   DRUGS

Glucocorticoid-Induced Leucine Zipper Inhibits Interferon-Gamma Production in B Cells and Suppresses Colitis in Mice

(2018) Stefano Bruscoli et al.   Frontiers in Immunology

GILZ restrains neutrophil activation by inhibiting the MAPK pathway

(2018) Erika Ricci et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Glucocorticoid-Induced Leucine Zipper Promotes Neutrophil and T-Cell Polarization with Protective Effects in Acute Kidney Injury

(2018) Babak Baban et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Insulin autoimmune syndrome

(2018) Fangyuan Chen et al.   MEDICINE

Treatment with Synthetic Glucocorticoids and the Hypothalamus-Pituitary-Adrenal Axis

(2017) Rosa Maria Paragliola et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Prevention and management of glucocorticoid-induced side effects: A comprehensive review

(2017) Avrom Caplan et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

First-line rituximab combined with short-term prednisone versus prednisone alone for the treatment of pemphigus (Ritux 3): a prospective, multicentre, parallel-group, open-label randomised trial

(2017) Pascal Joly et al.   LANCET

Long-term side effects of glucocorticoids

(2016) Merih Oray et al.   Expert Opinion On Drug Safety

Low expression of the GILZ may contribute to adipose inflammation and altered adipokine production in human obesity

(2016) Mi-Jeong Lee et al.   JOURNAL OF LIPID RESEARCH

Predictors of disease relapse in IgG4-related disease following rituximab

(2016) Zachary S. Wallace et al.   RHEUMATOLOGY

Systemic glucocorticoid therapy and adrenal insufficiency in adults: A systematic review

(2016) Rebecca M. Joseph et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Activation of the Glucocorticoid Receptor in Acute Inflammation: the SEDIGRAM Concept

(2016) Karolien De Bosscher et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Tofacitinib Citrate for Refractory Cutaneous Dermatomyositis

(2016) Drew J. B. Kurtzman et al.   JAMA Dermatology

Circadian Clocks, Stress, and Immunity

(2016) Rebecca Dumbell et al.   Frontiers in Endocrinology

Characterization of Pharmacologic and Pharmacokinetic Properties of CCX168, a Potent and Selective Orally Administered Complement 5a Receptor Inhibitor, Based on Preclinical Evaluation and Randomized Phase 1 Clinical Study

(2016) Pirow Bekker et al.   PLoS One

Overexpression of Glucocorticoid-induced Leucine Zipper (GILZ) increases susceptibility to Imiquimod-induced psoriasis and involves cutaneous activation of TGF-β1

(2016) Elena Carceller et al.   Scientific Reports

Glucocorticoid-induced leucine zipper (GILZ) inhibits B cell activation in systemic lupus erythematosus

(2015) Sarah A Jones et al.   ANNALS OF THE RHEUMATIC DISEASES

The Treg/Th17 cell ratio is reduced in the skin lesions of patients with pyoderma gangrenosum

(2015) M. Caproni et al.   BRITISH JOURNAL OF DERMATOLOGY

GILZ regulates Th17 responses and restrains IL-17-mediated skin inflammation

(2015) Sarah A. Jones et al.   JOURNAL OF AUTOIMMUNITY

The Role and Effects of Glucocorticoid-Induced Leucine Zipper in the Context of Inflammation Resolution

(2015) Juliana P. Vago et al.   JOURNAL OF IMMUNOLOGY

The role of adjuvant therapy in pemphigus: A systematic review and meta-analysis

(2015) Lihi Atzmony et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

One Hormone, Two Actions: Anti- and Pro-Inflammatory Effects of Glucocorticoids

(2015) Diana Cruz-Topete et al.   NEUROIMMUNOMODULATION

Selective glucocorticoid receptor modulation: New directions with non-steroidal scaffolds

(2015) Nora Sundahl et al.   PHARMACOLOGY & THERAPEUTICS

Interleukin-6 in ANCA-associated vasculitis: Rationale for successful treatment with tocilizumab

(2015) Alvise Berti et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Rare Disease Terminology and Definitions—A Systematic Global Review: Report of the ISPOR Rare Disease Special Interest Group

(2015) Trevor Richter et al.   VALUE IN HEALTH

Probability of remaining in unsustained complete remission after steroid therapy withdrawal in patients with primary warm-antibody reactive autoimmune hemolytic anemia

(2015) Johanna Kulpa et al.   WIENER KLINISCHE WOCHENSCHRIFT

GILZ as a Mediator of the Anti-Inflammatory Effects of Glucocorticoids

(2015) Simona Ronchetti et al.   Frontiers in Endocrinology

Downregulation of the glucocorticoid-induced leucine zipper (GILZ) promotes vascular inflammation

(2014) Rebecca T. Hahn et al.   ATHEROSCLEROSIS

Amendment of the Japanese Consensus Guidelines for Autoimmune Pancreatitis, 2013 III. Treatment and prognosis of autoimmune pancreatitis

(2014) Terumi Kamisawa et al.   JOURNAL OF GASTROENTEROLOGY

GILZ Promotes Production of Peripherally Induced Treg Cells and Mediates the Crosstalk between Glucocorticoids and TGF-β Signaling

(2014) Oxana Bereshchenko et al.   Cell Reports

Live Cell Imaging Unveils Multiple Domain Requirements for In Vivo Dimerization of the Glucocorticoid Receptor

(2014) Diego M. Presman et al.   PLOS BIOLOGY

A phase III randomized trial comparing glucocorticoid monotherapyversusglucocorticoid and rituximab in patients with autoimmune haemolytic anaemia

(2013) Henrik Birgens et al.   BRITISH JOURNAL OF HAEMATOLOGY

New Insights into the Anti-inflammatory Mechanisms of Glucocorticoids: An Emerging Role for Glucocorticoid-Receptor-Mediated Transactivation

(2013) Sofie Vandevyver et al.   ENDOCRINOLOGY

Pancreatobiliary reflux in individuals with a normal pancreaticobiliary junction: a prospective multicenter study

(2013) Jun Horaguchi et al.   JOURNAL OF GASTROENTEROLOGY

Plasma exchange and glucocorticoid dosing in the treatment of anti-neutrophil cytoplasm antibody associated vasculitis (PEXIVAS): protocol for a randomized controlled trial

(2013) Michael Walsh et al.   Trials

Salvage therapy of refractory hemophagocytic lymphohistiocytosis with alemtuzumab

(2012) Rebecca A. Marsh et al.   PEDIATRIC BLOOD & CANCER

Novel p65 Binding Glucocorticoid-induced Leucine Zipper Peptide Suppresses Experimental Autoimmune Encephalomyelitis

(2011) Mythily Srinivasan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucocorticoids Sensitize the Innate Immune System through Regulation of the NLRP3 Inflammasome

(2011) John M. Busillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional Regulation of Human Dual Specificity Protein Phosphatase 1 (DUSP1) Gene by Glucocorticoids

(2010) Lauren E. Shipp et al.   PLoS One

Glucocorticoid-induced leucine zipper (GILZ): a new important mediator of glucocorticoid action

(2009) Emira Ayroldi et al.   FASEB JOURNAL

Glucocorticoid resistance in inflammatory diseases

(2009) Peter J Barnes et al.   LANCET

Glucocorticoid-Induced Leucine Zipper Is Protective in Th1-Mediated Models of Colitis

(2008) Lorenza Cannarile et al.   GASTROENTEROLOGY