Deletion of Mir223 Exacerbates Lupus Nephritis by Targeting S1pr1 in Faslpr/lpr Mice

The Potential for microRNA Therapeutics and Clinical Research

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Innate Immune Cells' Contribution to Systemic Lupus Erythematosus

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MiRNA Regulation of MIF in SLE and Attenuation of Murine Lupus Nephritis With miR-654

(2019) Yang Tu et al.   Frontiers in Immunology

Siponimod in the treatment of multiple sclerosis

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miR-223-3p promotes autoreactive Th17 cell responses in experimental autoimmune uveitis (EAU) by inhibiting transcription factor FOXO3 expression

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MicroRNA miR-223 as regulator of innate immunity

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Ozanimod (RPC1063), a selective S1PR1 and S1PR5 modulator, reduces chronic inflammation and alleviates kidney pathology in murine systemic lupus erythematosus

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Essential Roles for Mannose-Binding Lectin-Associated Serine Protease-1/3 in the Development of Lupus-Like Glomerulonephritis in MRL/lpr Mice

(2018) Takeshi Machida et al.   Frontiers in Immunology

Neuropsychiatric Systemic Lupus Erythematosus Is Dependent on Sphingosine-1-Phosphate Signaling

(2018) Elise V. Mike et al.   Frontiers in Immunology

Downregulation of miR-200a-3p, Targeting CtBP2 Complex, Is Involved in the Hypoproduction of IL-2 in Systemic Lupus Erythematosus–Derived T Cells

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Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells

(2017) Alejandra Mendoza et al.   NATURE

The emerging role of miR-223 as novel potential diagnostic and therapeutic target for inflammatory disorders

(2016) Faisal Aziz   CELLULAR IMMUNOLOGY

Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential

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New insights into the immunopathogenesis of systemic lupus erythematosus

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Circulating hsa-miR-30e-5p, hsa-miR-92a-3p, and hsa-miR-223-3p may be novel biomarkers in systemic lupus erythematosus

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Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy

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miR-155 Deficiency Ameliorates Autoimmune Inflammation of Systemic Lupus Erythematosus by TargetingS1pr1inFaslpr/lprMice

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Homeostatic regulation of T cell trafficking by a B cell–derived peptide is impaired in autoimmune and chronic inflammatory disease

(2015) Myriam Chimen et al.   NATURE MEDICINE

Expanded Double Negative T Cells in Patients with Systemic Lupus Erythematosus Produce IL-17 and Infiltrate the Kidneys

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Circulating MicroRNA Expression Profiles Associated With Systemic Lupus Erythematosus

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miR-223: infection, inflammation and cancer

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Sphingosine-1-Phosphate and Lymphocyte Egress from Lymphoid Organs

(2012) Jason G. Cyster et al.   Annual Review of Immunology

Brief Report: Amelioration of collagen-induced arthritis in mice by lentivirus-mediated silencing of microRNA-223

(2012) Yuan-Tsung Li et al.   ARTHRITIS AND RHEUMATISM

A Novel Regulator of Macrophage Activation

(2012) Guoqing Zhuang et al.   CIRCULATION

The potential role of Th17 cells and Th17-related cytokines in the pathogenesis of lupus nephritis

(2012) D-Y Chen et al.   LUPUS

Circulating microRNAs as candidate biomarkers in patients with systemic lupus erythematosus

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Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression

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Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus

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Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

The lectin pathway and its implications in coagulation, infections and auto-immunity

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Adenosine 2A receptor is protective against renal injury in MRL/lpr mice

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Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

(2010) Volker Brinkmann et al.   NATURE REVIEWS DRUG DISCOVERY

miR-223 is overexpressed in T-lymphocytes of patients affected by rheumatoid arthritis

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T cells and dendritic cells in glomerular disease: the new glomerulotubular feedback loop

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Increased survival and reduced renal injury in MRL/lpr mice treated with a novel sphingosine-1-phosphate receptor agonist

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Regulation of progenitor cell proliferation and granulocyte function by microRNA-223

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