MnO 2 Nanoflowers Induce Immunogenic Cell Death under Nutrient Deprivation: Enabling an Orchestrated Cancer Starvation‐Immunotherapy

Immunogenic Cell Death and Immunotherapy of Multiple Myeloma

(2019) Alfonso Serrano-del Valle et al.   Frontiers in Cell and Developmental Biology

Transformable Nanoparticle‐Enabled Synergistic Elicitation and Promotion of Immunogenic Cell Death for Triple‐Negative Breast Cancer Immunotherapy

(2019) Chenfeng Xu et al.   ADVANCED FUNCTIONAL MATERIALS

NaCl Nanoparticles as a Cancer Therapeutic

(2019) Wen Jiang et al.   ADVANCED MATERIALS

Biodegradable Polymer Microparticles with Tunable Shapes and Surface Textures for Enhancement of Dendritic Cell Maturation

(2019) Mubashir Hussain et al.   ACS Applied Materials & Interfaces

Simultaneous Fenton-like Ion Delivery and Glutathione Depletion by MnO2 -Based Nanoagent to Enhance Chemodynamic Therapy

(2018) Li-Sen Lin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanoparticle-mediated Immunogenic Cell Death Enables and Potentiates Cancer Immunotherapy

(2018) Xiaopin Duan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Virus-Like Particle, Liposome, and Polymeric Particle-Based Vaccines against HIV-1

(2018) Yong Gao et al.   Frontiers in Immunology

Biomimetic nanoflowers by self-assembly of nanozymes to induce intracellular oxidative damage against hypoxic tumors

(2018) Zhenzhen Wang et al.   Nature Communications

A bifunctional nanomodulator for boosting CpG-mediated cancer immunotherapy

(2017) Zhenzhen Wang et al.   Nanoscale

Magnesium silicide nanoparticles as a deoxygenation agent for cancer starvation therapy

(2017) Chen Zhang et al.   Nature Nanotechnology

Hollow MnO2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses

(2017) Guangbao Yang et al.   Nature Communications

Biodegradable Hollow Mesoporous Silica Nanoparticles for Regulating Tumor Microenvironment and Enhancing Antitumor Efficiency

(2017) Miao Kong et al.   Theranostics

Intelligent Albumin-MnO2Nanoparticles as pH-/H2O2-Responsive Dissociable Nanocarriers to Modulate Tumor Hypoxia for Effective Combination Therapy

(2016) Qian Chen et al.   ADVANCED MATERIALS

Synthesis of NiO@MnO2 core/shell nanocomposites for supercapacitor application

(2016) Junjiao Chen et al.   APPLIED SURFACE SCIENCE

Inducing enhanced immunogenic cell death with nanocarrier-based drug delivery systems for pancreatic cancer therapy

(2016) Xiao Zhao et al.   BIOMATERIALS

Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth

(2016) Sung Eun Kim et al.   Nature Nanotechnology

Late-stage inhibition of autophagy enhances calreticulin surface exposure

(2016) Dan-Dan Li et al.   Oncotarget

Tumor resistance to vascular disrupting agents: mechanisms, imaging, and solutions

(2016) Wenjie Liang et al.   Oncotarget

A multifunctional core–shell nanoplatform for enhanced cancer cell apoptosis and targeted chemotherapy

(2016) Fei Zhou et al.   Journal of Materials Chemistry B

MnO2-Nanosheet-Modified Upconversion Nanosystem for Sensitive Turn-On Fluorescence Detection of H2O2 and Glucose in Blood

(2015) Jing Yuan et al.   ACS Applied Materials & Interfaces

Bioconjugated Manganese Dioxide Nanoparticles Enhance Chemotherapy Response by Priming Tumor-Associated Macrophages toward M1-like Phenotype and Attenuating Tumor Hypoxia

(2015) Manli Song et al.   ACS Nano

A Smart DNAzyme-MnO2Nanosystem for Efficient Gene Silencing

(2015) Huanhuan Fan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Break-up of Two-Dimensional MnO2Nanosheets Promotes Ultrasensitive pH-Triggered Theranostics of Cancer

(2014) Yu Chen et al.   ADVANCED MATERIALS

Antiangiogenesis Strategies Revisited: From Starving Tumors to Alleviating Hypoxia

(2014) Rakesh K. Jain   CANCER CELL

Nanometer-sized manganese oxide-quenched fluorescent oligonucleotides: an effective sensing platform for probing biomolecular interactions

(2014) Dinggeng He et al.   CHEMICAL COMMUNICATIONS

Activatable Fluorescence/MRI Bimodal Platform for Tumor Cell Imaging via MnO2 Nanosheet–Aptamer Nanoprobe

(2014) Zilong Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

ER stress, autophagy and immunogenic cell death in photodynamic therapy-induced anti-cancer immune responses

(2014) Abhishek D. Garg et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

DMXAA Causes Tumor Site-Specific Vascular Disruption in Murine Non-Small Cell Lung Cancer, and like the Endogenous Non-Canonical Cyclic Dinucleotide STING Agonist, 2′3′-cGAMP, Induces M2 Macrophage Repolarization

(2014) Charlene M. Downey et al.   PLoS One

Multimodal immunogenic cancer cell death as a consequence of anticancer cytotoxic treatments

(2013) H Inoue et al.   CELL DEATH AND DIFFERENTIATION

Inducers of immunogenic cancer cell death

(2013) Aleksandra M. Dudek et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Tuning Innate Immune Activation by Surface Texturing of Polymer Microparticles: The Role of Shape in Inflammasome Activation

(2013) C. A. Vaine et al.   JOURNAL OF IMMUNOLOGY

Glutathione participates in the modulation of starvation-induced autophagy in carcinoma cells

(2012) Enrico Desideri et al.   Autophagy

Glutathione synthesis

(2012) Shelly C. Lu   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

5,6-Dimethylxanthenone-4-acetic Acid (DMXAA) Activates Stimulator of Interferon Gene (STING)-dependent Innate Immune Pathways and Is Regulated by Mitochondrial Membrane Potential

(2012) Daniel Prantner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The secret ally: immunostimulation by anticancer drugs

(2012) Lorenzo Galluzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Raising the Bar: The Curative Potential of Human Cancer Immunotherapy

(2012) S. A. Rosenberg   Science Translational Medicine

Intracellular Glutathione Detection Using MnO2-Nanosheet-Modified Upconversion Nanoparticles

(2011) Renren Deng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE