Four sesquiterpene glycosides from loquat (Eriobotrya japonica) leaf ameliorates palmitic acid-induced insulin resistance and lipid accumulation in HepG2 Cells via AMPK signaling pathway

Polysaccharides from loquat (Eriobotrya japonica) leaves: Impacts of extraction methods on their physicochemical characteristics and biological activities

(2020) Yuan Fu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Neutrophil elastase inhibitory effects of pentacyclic triterpenoids from Eriobotrya japonica (loquat leaves)

(2019) Jie Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Aspalathin-Enriched Green Rooibos Extract Reduces Hepatic Insulin Resistance by Modulating PI3K/AKT and AMPK Pathways

(2019) Sithandiwe Mazibuko-Mbeje et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pterostilbene reverses palmitic acid mediated insulin resistance in HepG2 cells by reducing oxidative stress and triglyceride accumulation

(2019) Sajad Ahmad Malik et al.   FREE RADICAL RESEARCH

Eriobotrya japonica leaf extract attenuates airway inflammation in ovalbumin-induced mice model of asthma

(2019) Tae-muk Kim et al.   JOURNAL OF ETHNOPHARMACOLOGY

WITHDRAWN: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition

(2019) Pouya Saeedi et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Physicochemical characteristics and biological activities of polysaccharides from the leaves of different loquat (Eriobotrya japonica) cultivars

(2019) Yuan Fu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Sonchus oleraceus Linn extract enhanced glucose homeostasis through the AMPK/Akt/ GSK-3β signaling pathway in diabetic liver and HepG2 cell culture

(2019) Lei Chen et al.   FOOD AND CHEMICAL TOXICOLOGY

A novel sesquiterpene glycoside from Loquat leaf alleviates oleic acid-induced steatosis and oxidative stress in HepG2 cells

(2018) Tunyu Jian et al.   BIOMEDICINE & PHARMACOTHERAPY

Melatonin improves insulin resistance and hepatic steatosis through attenuation of alpha-2-HS-glycoprotein

(2018) Jee-In Heo et al.   JOURNAL OF PINEAL RESEARCH

Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway

(2018) Jiting Yan et al.   PHARMACOLOGICAL RESEARCH

Prolonged high-glucose exposure decreased SREBP-1/FASN/ACC in Schwann cells of diabetic mice via blocking PI3K/Akt pathway

(2018) Lin Zhu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Theaflavins Improve Insulin Sensitivity through Regulating Mitochondrial Biosynthesis in Palmitic Acid-Induced HepG2 Cells

(2018) Tuantuan Tong et al.   MOLECULES

Baicalin and its metabolites suppresses gluconeogenesis through activation of AMPK or AKT in insulin resistant HepG-2 cells

(2017) Tao Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

AMPK: guardian of metabolism and mitochondrial homeostasis

(2017) Sébastien Herzig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Diosgenin ameliorates gestational diabetes through inhibition of sterol regulatory element-binding protein-1

(2016) Shaofang Hua et al.   BIOMEDICINE & PHARMACOTHERAPY

A New Sesquiterpene Glycoside from the Leaves of Eriobotrya japonica

(2015) Lei Zhao et al.   CHEMISTRY OF NATURAL COMPOUNDS

Sterol Regulatory Element-binding Protein-1 (SREBP-1) Is Required to Regulate Glycogen Synthesis and Gluconeogenic Gene Expression in Mouse Liver

(2014) Rafaela Ruiz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 Diabetes

(2013) Andreas L. Birkenfeld et al.   HEPATOLOGY

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

Emerging role of AMP-activated protein kinase in endocrine control of metabolism in the liver

(2012) Clinton M. Hasenour et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

(2011) Yu Li et al.   Cell Metabolism

Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes

(2009) R. A. DeFronzo et al.   DIABETES CARE

Defining and Characterizing the Progression of Type 2 Diabetes

(2009) V. A. Fonseca   DIABETES CARE

Hypoglycemic effect of the total flavonoid fraction from Folium Eriobotryae

(2009) H. Lü et al.   PHYTOMEDICINE

Citrate diminishes hypothalamic acetyl-CoA carboxylase phosphorylation and modulates satiety signals and hepatic mechanisms involved in glucose homeostasis in rats

(2008) Maristela Cesquini et al.   LIFE SCIENCES

Hypoglycemic effects of a sesquiterpene glycoside isolated from leaves of loquat (Eriobotrya japonica (Thunb.) Lindl.)

(2007) J. Chen et al.   PHYTOMEDICINE