Overexpression of circRNA circUCK2 Attenuates Cell Apoptosis in Cerebral Ischemia-Reperfusion Injury via miR-125b-5p/GDF11 Signaling

LncRNA DANCR attenuates brain microvascular endothelial cell damage induced by oxygen-glucose deprivation through regulating of miR-33a-5p/XBP1s

(2020) Mengqi Zhang et al.   Aging-US

Acetate attenuates perioperative neurocognitive disorders in aged mice

(2020) Cen Wen et al.   Aging-US

MicroRNA-384-5p Promotes Endothelial Progenitor Cell Proliferation and Angiogenesis in Cerebral Ischemic Stroke through the Delta-Likeligand 4-Mediated Notch Signaling Pathway

(2020) Jia Fan et al.   CEREBROVASCULAR DISEASES

Rapid degeneration of neurons in the penumbra region following a small, focal ischemic stroke

(2020) Kathleen E. Fifield et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Targeted tPA overexpression in denervated spinal motor neurons promotes stroke recovery in mice

(2020) Xinling Gan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

CircRNA-AKT1 sequesters miR-942-5p to upregulate AKT1 and promote cervical cancer progression

(2020) Rongying Ou et al.   Molecular Therapy-Nucleic Acids

CircRNA-CIDN mitigated compression loading-induced damage in human nucleus pulposus cells via miR-34a-5p/SIRT1 axis

(2020) Qian Xiang et al.   EBioMedicine

Growth differentiation factor-11 supplementation improves survival and promotes recovery after ischemic stroke in aged mice

(2020) Jacob Hudobenko et al.   Aging-US

Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective

(2020) M. Iqbal Hossain et al.   Autophagy

Extracellular Vesicle-Mediated Delivery of CircSCMH1 Promotes Functional Recovery in Rodent and Nonhuman Primate Ischemic Stroke Models

(2020) Li Yang et al.   CIRCULATION

Autophagy-associated circRNA circCDYL augments autophagy and promotes breast cancer progression

(2020) Gehao Liang et al.   Molecular Cancer

PERK (Protein Kinase RNA-Like ER Kinase) Branch of the Unfolded Protein Response Confers Neuroprotection in Ischemic Stroke by Suppressing Protein Synthesis

(2020) Ya-chao Wang et al.   STROKE

Highly bioactive zeolitic imidazolate framework-8–capped nanotherapeutics for efficient reversal of reperfusion-induced injury in ischemic stroke

(2020) Lizhen He et al.   Science Advances

Circular RNA circDLGAP4 is involved in lung cancer development through modulating microRNA-143/CDK1 axis

(2020) Bin Wang et al.   CELL CYCLE

MiRNA-339-5p suppresses the malignant development of gastric cancer via targeting ALKBH1

(2020) Chenchen Wang et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

MicroRNA-665-3p attenuates oxygen-glucose deprivation-evoked microglial cell apoptosis and inflammatory response by inhibiting NF-κB signaling via targeting TRIM8

(2020) Xiajing Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Circulating circRNA predicting the occurrence of hepatocellular carcinoma in patients with HBV infection

(2020) Chen Wu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Plasma endothelial microvesicles and their carrying miRNA‐155 serve as biomarkers for ischemic stroke

(2020) Huiting Zhang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Upregulation of miRNA-9-5p Promotes Angiogenesis after Traumatic Brain Injury by Inhibiting Ptch-1

(2020) Jingchuan Wu et al.   NEUROSCIENCE

The Protective Effect of Safinamide in Ischemic Stroke Mice and a Brain Endothelial Cell Line

(2020) Tingting Xu et al.   NEUROTOXICITY RESEARCH

Hsa_circRNA_000166 Promotes Cell Proliferation, Migration and Invasion by Regulating miR-330-5p/ELK1 in Colon Cancer

(2020) Gang Zhao et al.   OncoTargets and Therapy

Neuroprotective and Anti-neuroinflammatory Properties of Ebselen Derivatives and Their Potential to Inhibit Neurodegeneration

(2020) Alexander D. Landgraf et al.   ACS Chemical Neuroscience

The role of miRNA-155 in the immunopathogenesis of obliterative airway disease in mice induced by circulating exosomes from human lung transplant recipients with chronic lung allograft dysfunction

(2020) Sandhya Bansal et al.   CELLULAR IMMUNOLOGY

Endothelin-1-mediated cerebral ischemia in mice: early cellular events and the role of caspase-3

(2019) Chesarahmia Dojo Soeandy et al.   APOPTOSIS

Mutations in GDF11 and the extracellular antagonist, Follistatin, as a likely cause of Mendelian forms of orofacial clefting in humans

(2019) Timothy C. Cox et al.   HUMAN MUTATION

Circular RNA TLK1 aggravates neuronal injury and neurological deficits after ischemic stroke via miR-335-3p/TIPARP

(2019) Fangfang Wu et al.   JOURNAL OF NEUROSCIENCE

Circular RNA circSLC8A1 acts as a sponge of miR-130b/miR-494 in suppressing bladder cancer progression via regulating PTEN

(2019) Qun Lu et al.   Molecular Cancer

Homocysteine enhances neural stem cell autophagy in in vivo and in vitro model of ischemic stroke

(2019) Mengying Wang et al.   Cell Death & Disease

The Integrative Regulatory Network of circRNA, microRNA, and mRNA in Atrial Fibrillation

(2019) Shengyang Jiang et al.   Frontiers in Genetics

CircRNA expression profiles and function prediction in peripheral blood mononuclear cells of patients with acute ischemic stroke

(2019) Zhaofei Dong et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Increased plasma levels of miR-124-3p, miR-125b-5p and miR-192-5p are associated with outcomes in acute ischaemic stroke patients receiving thrombolysis

(2019) Xin-Wei He et al.   ATHEROSCLEROSIS

TGF-β2/Smad3 Signaling Pathway Activation Through Enhancing VEGF and CD34 Ameliorates Cerebral Ischemia/Reperfusion Injury After Isoflurane Post-conditioning in Rats

(2019) Li Peng et al.   NEUROCHEMICAL RESEARCH

MiR-92a regulates endothelial progenitor cells (EPCs) by targeting GDF11 via activate SMAD2/3/FAK/Akt/eNOS pathway

(2019) Hai-Tao Huang et al.   Annals of Translational Medicine

MiR-340-5p alleviates oxygen-glucose deprivation/reoxygenation-induced neuronal injury via PI3K/Akt activation by targeting PDCD4

(2019) Yake Zheng et al.   NEUROCHEMISTRY INTERNATIONAL

Circulating Circular RNAs as Biomarkers for the Diagnosis and Prediction of Outcomes in Acute Ischemic Stroke

(2019) Lei Zuo et al.   STROKE

Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition

(2018) Li Yang et al.   Autophagy

CircRNA circHIPK3 serves as a prognostic marker to promote glioma progression by regulating miR-654/IGF2BP3 signaling

(2018) Pengcheng Jin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Growth differentiation factor 11 improves neurobehavioral recovery and stimulates angiogenesis in rats subjected to cerebral ischemia/reperfusion

(2018) Jingxi Ma et al.   BRAIN RESEARCH BULLETIN

Neonatal Systemic AAV-Mediated Gene Delivery of GDF11 Inhibits Skeletal Muscle Growth

(2018) Quan Jin et al.   MOLECULAR THERAPY

Thrombolytic fucoidans inhibit the tPA-PAI1 complex, indicating activation of plasma tissue-type plasminogen activator is a mechanism of fucoidan-mediated thrombolysis in a mouse thrombosis model

(2018) Younshick Choi et al.   THROMBOSIS RESEARCH

circHIPK3 regulates cell proliferation and migration by sponging miR-124 and regulating AQP3 expression in hepatocellular carcinoma

(2018) Genwen Chen et al.   Cell Death & Disease

Retrovirus-Mediated Transfection of the Tissue-type Plasminogen Activator Gene Results in Increased Thrombolysis of Blood Clots

(2018) Xianhua Wu et al.   BIOCHEMICAL GENETICS

CircRNA_001569 promotes cell proliferation through absorbing miR-145 in gastric cancer

(2018) Fengqian Shen et al.   JOURNAL OF BIOCHEMISTRY

Behavioral tests that reveal long-term deficits after permanent focal cerebral ischemia in mouse

(2018) Magalie Fréchou et al.   BEHAVIOURAL BRAIN RESEARCH

In Vitro Evaluation of Focused Ultrasound-Enhanced TNK-Tissue Plasminogen Activator-Mediated Thrombolysis

(2016) Nikolaos Papadopoulos et al.   Journal of Stroke & Cerebrovascular Diseases

Transcutaneous auricular vagus nerve stimulation regulates expression of growth differentiation factor 11 and activin-like kinase 5 in cerebral ischemia/reperfusion rats

(2016) Jingxi Ma et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

(2016) Qiupeng Zheng et al.   Nature Communications

In Vitro Evaluation of Focused Ultrasound-Enhanced TNK-Tissue Plasminogen Activator-Mediated Thrombolysis

(2016) Nikolaos Papadopoulos et al.   Journal of Stroke & Cerebrovascular Diseases

Association of growth differentiation factor 11/8, putative anti-ageing factor, with cardiovascular outcomes and overall mortality in humans: analysis of the Heart and Soul and HUNT3 cohorts

(2015) Kristoff A. Olson et al.   EUROPEAN HEART JOURNAL

Acceleration of Tissue Plasminogen Activator-Mediated Thrombolysis by Magnetically Powered Nanomotors

(2014) Rui Cheng et al.   ACS Nano

Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice

(2014) Jesús Planagumà et al.   BRAIN