Brain NAD Is Associated With ATP Energy Production and Membrane Phospholipid Turnover in Humans

Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing

(2020) Brian C. Gilmour et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Diet modulates brain network stability, a biomarker for brain aging, in young adults

(2020) Lilianne R. Mujica-Parodi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-related NAD+ decline

(2020) Melanie R. McReynolds et al.   EXPERIMENTAL GERONTOLOGY

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

(2020) Stephen C. Cunnane et al.   NATURE REVIEWS DRUG DISCOVERY

The wrinkling of time: Aging, inflammation, oxidative stress, and the circadian clock in neurodegeneration

(2020) Brian V. Lananna et al.   NEUROBIOLOGY OF DISEASE

Blood NAD levels are reduced in very old patients hospitalized for heart failure

(2020) Marie Breton et al.   EXPERIMENTAL GERONTOLOGY

Links Between Metabolic and Structural Changes in the Brain of Cognitively Normal Older Adults: A 4-Year Longitudinal Follow-Up

(2019) Christian-Alexandre Castellano et al.   Frontiers in Aging Neuroscience

Single‐Voxel 1 H MR spectroscopy of cerebral nicotinamide adenine dinucleotide (NAD + ) in humans at 7T using a 32‐channel volume coil

(2019) Puneet Bagga et al.   MAGNETIC RESONANCE IN MEDICINE

NAD+ in Brain Aging and Neurodegenerative Disorders

(2019) Sofie Lautrup et al.   Cell Metabolism

NAD(H) and NADP(H) Redox Couples and Cellular Energy Metabolism

(2018) Wusheng Xiao et al.   ANTIOXIDANTS & REDOX SIGNALING

Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence

(2018) Luis Rajman et al.   Cell Metabolism

Functional energetic responses and individual variance of the human brain revealed by quantitative imaging of adenosine triphosphate production rates

(2018) Xiao-Hong Zhu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Effects of Aging on the Human Brain: A Proton and Phosphorus MR Spectroscopy Study at 3T

(2018) Birte Schmitz et al.   JOURNAL OF NEUROIMAGING

Metabolic aspects of neuronal degeneration: From a NAD + point of view

(2018) Yo Sasaki   NEUROSCIENCE RESEARCH

Characterization of Brain Metabolism by Nuclear Magnetic Resonance

(2018) Daniel P. Downes et al.   CHEMPHYSCHEM

Brain Glucose Metabolism: Integration of Energetics with Function

(2018) Gerald A. Dienel   PHYSIOLOGICAL REVIEWS

In vivo X-Nuclear MRS Imaging Methods for Quantitative Assessment of Neuroenergetic Biomarkers in Studying Brain Function and Aging

(2018) Xiao-Hong Zhu et al.   Frontiers in Aging Neuroscience

Pathways to Brain Aging and Their Modifiers: Free-Radical-Induced Energetic and Neural Decline in Senescence (FRIENDS) Model - A Mini-Review

(2017) Naftali Raz et al.   GERONTOLOGY

Imaging and spectroscopic approaches to probe brain energy metabolism dysregulation in neurodegenerative diseases

(2017) Gilles Bonvento et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The brain, sirtuins, and ageing

(2017) Akiko Satoh et al.   NATURE REVIEWS NEUROSCIENCE

Brain bioenergetics and redox state measured by 31 P magnetic resonance spectroscopy in unaffected siblings of patients with psychotic disorders

(2017) Virginie-Anne Chouinard et al.   SCHIZOPHRENIA RESEARCH

Bioenergetic state regulates innate inflammatory responses through the transcriptional co-repressor CtBP

(2017) Yiguo Shen et al.   Nature Communications

Age-Related Gray and White Matter Changes in Normal Adult Brains

(2017) Farnaz Farokhian et al.   Aging and Disease

Abnormalities in High-Energy Phosphate Metabolism in First-Episode Bipolar Disorder Measured Using 31P-Magnetic Resonance Spectroscopy

(2017) Fei Du et al.   BIOLOGICAL PSYCHIATRY

Cellular compartmentation of energy metabolism: creatine kinase microcompartments and recruitment of B-type creatine kinase to specific subcellular sites

(2016) Uwe Schlattner et al.   AMINO ACIDS

Electroencephalographic Fractal Dimension in Healthy Ageing and Alzheimer’s Disease

(2016) Fenne Margreeth Smits et al.   PLoS One

Redox Dysregulation in Schizophrenia Revealed by in vivo NAD+/NADH Measurement

(2016) Sang-Young Kim et al.   SCHIZOPHRENIA BULLETIN

In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences

(2015) Xiao-Hong Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NAD+ in aging, metabolism, and neurodegeneration

(2015) E. Verdin   SCIENCE

Dissociated Expression of Mitochondrial and Cytosolic Creatine Kinases in the Human Brain: A New Perspective on the Role of Creatine in Brain Energy Metabolism

(2013) Matthew TJ Lowe et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

In Vivo Evidence for Cerebral Bioenergetic Abnormalities in Schizophrenia Measured Using31P Magnetization Transfer Spectroscopy

(2013) Fei Du et al.   JAMA Psychiatry

Circadian clocks in human red blood cells

(2011) John S. O’Neill et al.   NATURE

Altered Brain Mitochondrial Metabolism in Healthy Aging as Assessed by in vivo Magnetic Resonance Spectroscopy

(2009) Fawzi Boumezbeur et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Age-related changes in brain energetics and phospholipid metabolism

(2009) Brent P. Forester et al.   NMR IN BIOMEDICINE

NAD+/NADH and NADP+/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences

(2007) Weihai Ying   ANTIOXIDANTS & REDOX SIGNALING