The Histone Methyltransferase DOT1L Is Essential for Humoral Immune Responses
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Histone Methyltransferase DOT1L Is Essential for Humoral Immune Responses
Authors
Keywords
B cells, antibody, epigenetics, DOT1L, humoral responses, H3K79
Journal
Cell Reports
Volume 33, Issue 11, Pages 108504
Publisher
Elsevier BV
Online
2020-12-16
DOI
10.1016/j.celrep.2020.108504
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Epigenetic regulation of B cell fate and function during an immune response
- (2019) Yan Zhang et al. IMMUNOLOGICAL REVIEWS
- G‐protein coupled receptors and ligands that organize humoral immune responses
- (2019) Erick Lu et al. IMMUNOLOGICAL REVIEWS
- Restricted Clonality and Limited Germinal Center Reentry Characterize Memory B Cell Reactivation by Boosting
- (2019) Luka Mesin et al. CELL
- Strength in diversity: Phenotypic, functional, and molecular heterogeneity within the memory B cell repertoire
- (2018) Kim L. Good-Jacobson IMMUNOLOGICAL REVIEWS
- Atypical chemokine receptor 4 shapes activated B cell fate
- (2018) Ervin E. Kara et al. JOURNAL OF EXPERIMENTAL MEDICINE
- An epigenetic regulator-related score (EpiScore) predicts survival in patients with diffuse large B cell lymphoma and identifies patients who may benefit from epigenetic therapy
- (2018) Vanessa Szablewski et al. Oncotarget
- The Histone Demethylase LSD1 Regulates B Cell Proliferation and Plasmablast Differentiation
- (2018) Robert R. Haines et al. JOURNAL OF IMMUNOLOGY
- B cells turn on, tune in with LSD1
- (2018) Kim L. Good-Jacobson NATURE IMMUNOLOGY
- Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis
- (2018) Katerina Hatzi et al. NATURE IMMUNOLOGY
- Assessing the role of the T-box transcription factor Eomes in B cell differentiation during either Th1 or Th2 cell-biased responses
- (2018) Lucy Cooper et al. PLoS One
- A chemical biology toolbox to study protein methyltransferases and epigenetic signaling
- (2018) Sebastian Scheer et al. Nature Communications
- EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop
- (2017) Wendy Béguelin et al. Nature Communications
- c-Myb Regulates the T-Bet-Dependent Differentiation Program in B Cells to Coordinate Antibody Responses
- (2017) Dana Piovesan et al. Cell Reports
- Somatically Hypermutated Plasmodium-Specific IgM+ Memory B Cells Are Rapid, Plastic, Early Responders upon Malaria Rechallenge
- (2016) Akshay T. Krishnamurty et al. IMMUNITY
- Mixed lineage rearranged leukaemia
- (2015) Eytan M. Stein et al. CURRENT OPINION IN HEMATOLOGY
- An epigenetic view of B-cell disorders
- (2015) Federica Alberghini et al. IMMUNOLOGY AND CELL BIOLOGY
- Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis
- (2015) Jiyuan Zhang et al. NATURE MEDICINE
- Transcription Factor IRF4 Regulates Germinal Center Cell Formation through a B Cell-Intrinsic Mechanism
- (2014) S. N. Willis et al. JOURNAL OF IMMUNOLOGY
- Regulation of germinal center responses and B-cell memory by the chromatin modifier MOZ
- (2014) Kim L. Good-Jacobson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- voom: precision weights unlock linear model analysis tools for RNA-seq read counts
- (2014) Charity W Law et al. GENOME BIOLOGY
- featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
- (2013) Y. Liao et al. BIOINFORMATICS
- EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation
- (2013) Wendy Béguelin et al. CANCER CELL
- Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis
- (2013) Marieta Caganova et al. JOURNAL OF CLINICAL INVESTIGATION
- Acute lymphoblastic leukaemia
- (2013) Hiroto Inaba et al. LANCET
- The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway
- (2013) Lucille C Rankin et al. NATURE IMMUNOLOGY
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- S1PR2 links germinal center confinement and growth regulation
- (2012) Jesse A. Green et al. IMMUNOLOGICAL REVIEWS
- Epigenetic protein families: a new frontier for drug discovery
- (2012) Cheryl H. Arrowsmith et al. NATURE REVIEWS DRUG DISCOVERY
- Integrative Epigenomic Analysis Identifies Biomarkers and Therapeutic Targets in Adult B-Acute Lymphoblastic Leukemia
- (2012) Huimin Geng et al. Cancer Discovery
- Universal expression and dual function of the atypical chemokine receptor D6 on innate-like B cells in mice
- (2011) C. A. H. Hansell et al. BLOOD
- MLL-Rearranged Leukemia Is Dependent on Aberrant H3K79 Methylation by DOT1L
- (2011) Kathrin M. Bernt et al. CANCER CELL
- Germinal Center B Cell and T Follicular Helper Cell Development Initiates in the Interfollicular Zone
- (2011) Steven M. Kerfoot et al. IMMUNITY
- Bcl6 Protein Expression Shapes Pre-Germinal Center B Cell Dynamics and Follicular Helper T Cell Heterogeneity
- (2011) Masahiro Kitano et al. IMMUNITY
- The Eleven-Nineteen Lysine-rich Leukemia Gene (ELL2) Influences the Histone H3 Protein Modifications Accompanying the Shift to Secretory Immunoglobulin Heavy Chain mRNA Production
- (2011) Christine Milcarek et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Different B Cell Populations Mediate Early and Late Memory During an Endogenous Immune Response
- (2011) K. A. Pape et al. SCIENCE
- Plasticity and Heterogeneity in the Generation of Memory B Cells and Long-Lived Plasma Cells: The Influence of Germinal Center Interactions and Dynamics
- (2010) K. L. Good-Jacobson et al. JOURNAL OF IMMUNOLOGY
- A scaling normalization method for differential expression analysis of RNA-seq data
- (2010) Mark D Robinson et al. GENOME BIOLOGY
- Antigen Affinity Controls Rapid T-Dependent Antibody Production by Driving the Expansion Rather than the Differentiation or Extrafollicular Migration of Early Plasmablasts
- (2009) T. D. Chan et al. JOURNAL OF IMMUNOLOGY
- Multiple layers of B cell memory with different effector functions
- (2009) Ismail Dogan et al. NATURE IMMUNOLOGY
- H3K79 Methylation Profiles Define Murine and Human MLL-AF4 Leukemias
- (2008) Andrei V. Krivtsov et al. CANCER CELL
- Instructive Role of the Transcription Factor E2A in Early B Lymphopoiesis and Germinal Center B Cell Development
- (2008) Kyongrim Kwon et al. IMMUNITY
- DOT1L/KMT4 Recruitment and H3K79 Methylation Are Ubiquitously Coupled with Gene Transcription in Mammalian Cells
- (2008) D. J. Steger et al. MOLECULAR AND CELLULAR BIOLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started