S1PR2 links germinal center confinement and growth regulation

The Effect of Deleting p110  on the Phenotype and Function of PTEN-Deficient B Cells

(2014) M. L. Janas et al.   JOURNAL OF IMMUNOLOGY

Sphingosine-1-Phosphate and Lymphocyte Egress from Lymphoid Organs

(2012) Jason G. Cyster et al.   Annual Review of Immunology

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

Germinal Center B Cell and T Follicular Helper Cell Development Initiates in the Interfollicular Zone

(2011) Steven M. Kerfoot et al.   IMMUNITY

Bcl6 Protein Expression Shapes Pre-Germinal Center B Cell Dynamics and Follicular Helper T Cell Heterogeneity

(2011) Masahiro Kitano et al.   IMMUNITY

Lipid phosphate phosphatase 3 enables efficient thymic egress

(2011) Béatrice Bréart et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Follicular dendritic cells help establish follicle identity and promote B cell retention in germinal centers

(2011) Xiaoming Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Distinct Waves of BCL6 Expression during T Follicular Helper Cell Development

(2011) D. Baumjohann et al.   JOURNAL OF IMMUNOLOGY

EBI2 Guides Serial Movements of Activated B Cells and Ligand Activity Is Detectable in Lymphoid and Nonlymphoid Tissues

(2011) L. M. Kelly et al.   JOURNAL OF IMMUNOLOGY

Oxysterols direct B-cell migration through EBI2

(2011) Changlu Liu et al.   NATURE

Oxysterols direct immune cell migration via EBI2

(2011) Sébastien Hannedouche et al.   NATURE

The sphingosine 1-phosphate receptor S1P2 maintains the homeostasis of germinal center B cells and promotes niche confinement

(2011) Jesse A Green et al.   NATURE IMMUNOLOGY

B cells within germinal centers migrate preferentially from dark to light zone

(2011) J. B. Beltman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sphingosine-1-Phosphate Receptor-2 Function in Myeloid Cells Regulates Vascular Inflammation and Atherosclerosis

(2010) Athanasia Skoura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter

(2010) Gabriel D. Victora et al.   CELL

Optimal Germinal Center Responses Require a Multistage T Cell:B Cell Adhesion Process Involving Integrins, SLAM-Associated Protein, and CD84

(2010) Jennifer L. Cannons et al.   IMMUNITY

Finding the right niche: B-cell migration in the early phases of T-dependent antibody responses

(2010) J. P. Pereira et al.   INTERNATIONAL IMMUNOLOGY

Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice

(2010) Fei Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo

(2010) Masaru Ishii et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Essential roles of sphingosine-1–phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema

(2010) Carole A. Oskeritzian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bam32/DAPP1 Promotes B Cell Adhesion and Formation of Polarized Conjugates with T Cells

(2010) M. Al-Alwan et al.   JOURNAL OF IMMUNOLOGY

Akt Contributes to Activation of the TRIF-Dependent Signaling Pathways of TLRs by Interacting with TANK-Binding Kinase 1

(2010) S. M. Joung et al.   JOURNAL OF IMMUNOLOGY

Phosphoinositide 3-Kinase Activity in T Cells Regulates the Magnitude of the Germinal Center Reaction

(2010) J. Rolf et al.   JOURNAL OF IMMUNOLOGY

Control systems and decision making for antibody production

(2010) Christopher C Goodnow et al.   NATURE IMMUNOLOGY

B cell follicles and antigen encounters of the third kind

(2010) Jason G Cyster   NATURE IMMUNOLOGY

The PI3K Isoforms p110  and p110  Are Essential for Pre-B Cell Receptor Signaling and B Cell Development

(2010) F. Ramadani et al.   Science Signaling

Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells

(2009) K. Basso et al.   BLOOD

AID constrains germinal center size by rendering B cells susceptible to apoptosis

(2009) A. Zaheen et al.   BLOOD

Targeted Disruption of the S1P2 Sphingosine 1-Phosphate Receptor Gene Leads to Diffuse Large B-Cell Lymphoma Formation

(2009) G. Cattoretti et al.   CANCER RESEARCH

PI3 Kinase Signals BCR-Dependent Mature B Cell Survival

(2009) Lakshmi Srinivasan et al.   CELL

The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment

(2009) Di Yu et al.   IMMUNITY

B Lymphocytes Exit Lymph Nodes through Cortical Lymphatic Sinusoids by a Mechanism Independent of Sphingosine-1-Phosphate-Mediated Chemotaxis

(2009) Rajesh K. Sinha et al.   IMMUNITY

Initial Clonal Expansion of Germinal Center B Cells Takes Place at the Perimeter of Follicles

(2009) Francis Coffey et al.   IMMUNITY

Guidance of B Cells by the Orphan G Protein-Coupled Receptor EBI2 Shapes Humoral Immune Responses

(2009) Dominique Gatto et al.   IMMUNITY

Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

(2009) Trung H.M. Pham et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Pleckstrin Homology Domain Adaptor Protein Bam32/DAPP1 Is Required for Germinal Center Progression

(2009) Ting-ting Zhang et al.   JOURNAL OF IMMUNOLOGY

Inhibitory Role of Sphingosine 1-Phosphate Receptor 2 in Macrophage Recruitment during Inflammation

(2009) J. Michaud et al.   JOURNAL OF IMMUNOLOGY

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production

(2009) Katrina L Randall et al.   NATURE IMMUNOLOGY

Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation

(2009) Tri Giang Phan et al.   NATURE IMMUNOLOGY

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

Bcl6 Mediates the Development of T Follicular Helper Cells

(2009) R. I. Nurieva et al.   SCIENCE

G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase

(2008) Shin-ichiro Takashima et al.   CARDIOVASCULAR RESEARCH

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

Vascular Endothelium As a Contributor of Plasma Sphingosine 1-Phosphate

(2008) Krishnan Venkataraman et al.   CIRCULATION RESEARCH

Regulation of cAMP Responses by the G12/13 Pathway Converges on Adenylyl Cyclase VII

(2008) Lily I. Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SAP-controlled T–B cell interactions underlie germinal centre formation

(2008) Hai Qi et al.   NATURE

The p110  isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110 

(2008) J. Guillermet-Guibert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Follicular dendritic cell networks of primary follicles and germinal centers: Phenotype and function

(2008) Christopher D.C. Allen et al.   SEMINARS IN IMMUNOLOGY