Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer
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Title
Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer
Authors
Keywords
hypoxia, CRISPR library screening, liver cancer, metabolism, mitochondria, cardiolipin, electron transport chain, oxidative stress, ROS
Journal
Cell Reports
Volume 34, Issue 4, Pages 108676
Publisher
Elsevier BV
Online
2021-01-26
DOI
10.1016/j.celrep.2020.108676
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