Iron accumulation in macrophages promotes the formation of foam cells and development of atherosclerosis

Atherosclerosis is aggravated by iron overload and ameliorated by dietary and pharmacological iron restriction

(2019) Francesca Vinchi et al.   EUROPEAN HEART JOURNAL

Iron‐load exacerbates the severity of atherosclerosis via inducing inflammation and enhancing the glycolysis in macrophages

(2019) Xiaorong Hu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Chronic iron overload intensifies atherosclerosis in apolipoprotein E deficient mice: Role of oxidative stress and endothelial dysfunction

(2019) Vinícius Bermond Marques et al.   LIFE SCIENCES

The role of Kupffer cells in hepatic iron and lipid metabolism

(2018) Charlotte L. Scott et al.   JOURNAL OF HEPATOLOGY

Liver X receptors in lipid signalling and membrane homeostasis

(2018) Bo Wang et al.   Nature Reviews Endocrinology

Haemochromatosis

(2018) Pierre Brissot et al.   Nature Reviews Disease Primers

Hepcidin Deficiency Protects Against Atherosclerosis

(2018) Rajeev Malhotra et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Macrophage Phenotype and Function in Different Stages of Atherosclerosis

(2016) Ira Tabas et al.   CIRCULATION RESEARCH

Iron Together with Lipid Downregulates Protein Levels of Ceruloplasmin in Macrophages Associated with Rapid Foam Cell Formation

(2016) Qi Wang et al.   Journal of Atherosclerosis and Thrombosis

Macrophage Sortilin Promotes LDL Uptake, Foam Cell Formation, and Atherosclerosis

(2015) K. M. Patel et al.   CIRCULATION RESEARCH

Mitochondrion-Targeted Peptide SS-31 Inhibited Oxidized Low-Density Lipoproteins-Induced Foam Cell Formation through both ROS Scavenging and Inhibition of Cholesterol Influx in RAW264.7 Cells

(2015) Shuangying Hao et al.   MOLECULES

Atherogenesis and iron: from epidemiology to cellular level

(2014) Francesca Vinchi et al.   Frontiers in Pharmacology

Liver X Receptor Activation Stimulates Iron Export in Human Alternative Macrophages

(2013) Gaël Bories et al.   CIRCULATION RESEARCH

Testing the Iron Hypothesis in a Mouse Model of Atherosclerosis

(2013) Léon Kautz et al.   Cell Reports

Aging and Atherosclerosis

(2012) Julie C. Wang et al.   CIRCULATION RESEARCH

Ferroportin1 deficiency in mouse macrophages impairs iron homeostasis and inflammatory responses

(2011) Z. Zhang et al.   BLOOD

Hemoglobin Directs Macrophage Differentiation and Prevents Foam Cell Formation in Human Atherosclerotic Plaques

(2011) Aloke V. Finn et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Do Hemochromatosis Mutations Protect Against Iron-Mediated Atherogenesis?

(2009) Jerome L. Sullivan   Circulation-Cardiovascular Genetics

Iron in arterial plaque: A modifiable risk factor for atherosclerosis

(2008) Jerome L. Sullivan   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Forging a field: the golden age of iron biology

(2008) N. C. Andrews   BLOOD