Epithelial processed Mycobacterium avium subsp. paratuberculosis induced prolonged Th17 response and suppression of phagocytic maturation in bovine peripheral blood mononuclear cells

Transcriptome Profiling of Bovine Macrophages Infected by Mycobacterium avium spp. paratuberculosis Depicts Foam Cell and Innate Immune Tolerance Phenotypes

(2020) Olivier Ariel et al.   Frontiers in Immunology

Mycobacterium avium subspecies paratuberculosis is able to manipulate host lipid metabolism and accumulate cholesterol within macrophages

(2019) Matt D. Johansen et al.   MICROBIAL PATHOGENESIS

The Mycobacterium tuberculosis glycoprotein Rv1016c protein inhibits dendritic cell maturation, and impairs Th1 /Th17 responses during mycobacteria infection

(2019) Haibo Su et al.   MOLECULAR IMMUNOLOGY

RNA-Seq analysis of ileocecal valve and peripheral blood from Holstein cattle infected with Mycobacterium avium subsp. paratuberculosis revealed dysregulation of the CXCL8/IL8 signaling pathway

(2019) Marta Alonso-Hearn et al.   Scientific Reports

Expansion, isolation and first characterization of bovine Th17 lymphocytes

(2019) Patricia Cunha et al.   Scientific Reports

Mycobacterium avium sp. paratuberculosis (MAP) induces IL-17a production in bovine peripheral blood mononuclear cells (PBMCs) and enhances IL-23R expression in-vivo and in-vitro

(2019) Justin L. DeKuiper et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Inflammatory Th17 responses to infection with Mycobacterium avium subspecies paratuberculosis (MAP) in cattle and their potential role in development of Johne’s disease

(2019) Justin L. DeKuiper et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

The Immunoregulation of Th17 in Host against Intracellular Bacterial Infection

(2018) Yonghong Li et al.   MEDIATORS OF INFLAMMATION

Gene expression profiles of immune-regulatory genes in whole blood of cattle with a subclinical infection of Mycobacterium avium subsp. paratuberculosis

(2018) Hyun-Eui Park et al.   PLoS One

Mycobacterium tuberculosis Exploits a Molecular Off Switch of the Immune System for Intracellular Survival

(2018) Ulrich von Both et al.   Scientific Reports

IL-36/LXR axis modulates cholesterol metabolism and immune defense to Mycobacterium tuberculosis

(2018) Fadhil Ahsan et al.   Scientific Reports

Cholesterol and fatty acids grease the wheels of Mycobacterium tuberculosis pathogenesis

(2018) Kaley M Wilburn et al.   Pathogens and Disease

The Immunologic Role of IL-17 in Psoriasis and Psoriatic Arthritis Pathogenesis

(2018) Andrew Blauvelt et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Johne’s disease in cattle: an in vitro model to study early response to infection of Mycobacterium avium subsp. paratuberculosis using RNA-seq.

(2017) Rosanna Marino et al.   MOLECULAR IMMUNOLOGY

Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis

(2016) Tamer Sallam et al.   NATURE

Can Immune Response Mechanisms Explain the Fecal Shedding Patterns of Cattle Infected with Mycobacterium avium Subspecies paratuberculosis?

(2016) Gesham Magombedze et al.   PLoS One

Transcriptional Profiling of Ileocecal Valve of Holstein Dairy Cows Infected with Mycobacterium avium subsp. Paratuberculosis

(2016) Randy J. Hempel et al.   PLoS One

Whole-Blood Gene-Expression Profiles of Cows Infected with Mycobacterium avium subsp. paratuberculosis Reveal Changes in Immune Response and Lipid Metabolism

(2015) Min-Kyoung Shin et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Characterization of the inflammatory phenotype of Mycobacterium avium subspecies paratuberculosis using a novel cell culture passage model

(2015) Jamie L. Everman et al.   MICROBIOLOGY-SGM

Mycobacterium lepraeintracellular survival relies on cholesterol accumulation in infected macrophages: a potential target for new drugs for leprosy treatment

(2014) Katherine A. Mattos et al.   CELLULAR MICROBIOLOGY

Increased blood-circulating interferon-γ, interleukin-17, and osteopontin levels in bovine paratuberculosis

(2014) P.L. Dudemaine et al.   JOURNAL OF DAIRY SCIENCE

Liver X receptors in lipid metabolism: opportunities for drug discovery

(2014) Cynthia Hong et al.   NATURE REVIEWS DRUG DISCOVERY

Expression of genes associated with cholesterol and lipid metabolism identified as a novel pathway in the early pathogenesis of Mycobacterium avium subspecies paratuberculosis-infection in cattle

(2014) Shyamala Thirunavukkarasu et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

Host-Mycobacterium avium subsp. paratuberculosis interactome reveals a novel iron assimilation mechanism linked to nitric oxide stress during early infection

(2013) Elise A Lamont et al.   BMC GENOMICS

Strain specific transcriptional response in Mycobacterium tuberculosis infected macrophages

(2012) Mi-Sun Koo et al.   Cell Communication and Signaling

Surface Proteome of “Mycobacterium avium subsp. hominissuis” during the Early Stages of Macrophage Infection

(2012) Michael McNamara et al.   INFECTION AND IMMUNITY

IL-23-dependent IL-17 drives Th1-cell responses followingMycobacterium bovisBCG vaccination

(2011) Radha Gopal et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Conversion of Mycobacterium smegmatis to a pathogenic phenotype via passage of epithelial cells during macrophage infection

(2011) Su-Young Kim et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Pathogenesis of Paratuberculosis

(2011) Raymond W. Sweeney   VETERINARY CLINICS OF NORTH AMERICA-FOOD ANIMAL PRACTICE

Primary transcriptomes of Mycobacterium avium subsp. paratuberculosis reveal proprietary pathways in tissue and macrophages

(2010) Harish K Janagama et al.   BMC GENOMICS

Essential Role of IL-17A in the Formation of a Mycobacterial Infection-Induced Granuloma in the Lung

(2010) Y. Okamoto Yoshida et al.   JOURNAL OF IMMUNOLOGY

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

The role of interleukin-17 in the pathogenesis of rheumatoid arthritis

(2009) Sarah L. Gaffen   Current Rheumatology Reports

Live Mycobacterium avium subsp. paratuberculosis and a Killed-Bacterium Vaccine Induce Distinct Subcutaneous Granulomas, with Unique Cellular and Cytokine Profiles

(2008) L. Lei et al.   Clinical and Vaccine Immunology

Ante mortem diagnosis of paratuberculosis: A review of accuracies of ELISA, interferon-γ assay and faecal culture techniques

(2008) S.S. Nielsen et al.   VETERINARY MICROBIOLOGY