ZBP1 promotes LPS-induced cell death and IL-1β release via RHIM-mediated interactions with RIPK1

Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis

(2020) Ting Zhang et al.   CELL

cFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation

(2020) Hayley I. Muendlein et al.   SCIENCE

Yersinia pestis and plague: an updated view on evolution, virulence determinants, immune subversion, vaccination, and diagnostics

(2019) Christian E. Demeure et al.   GENES AND IMMUNITY

Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation

(2019) Yves Dondelinger et al.   Nature Communications

ZBP1/DAI Drives RIPK3-Mediated Cell Death Induced by IFNs in the Absence of RIPK1

(2019) Justin P. Ingram et al.   JOURNAL OF IMMUNOLOGY

TNFR1 and TNFR2 in the Control of the Life and Death Balance of Macrophages

(2019) Harald Wajant et al.   Frontiers in Cell and Developmental Biology

ZBP1 and TAK1: Master Regulators of NLRP3 Inflammasome/Pyroptosis, Apoptosis, and Necroptosis (PAN-optosis)

(2019) R. K. Subbarao Malireddi et al.   Frontiers in Cellular and Infection Microbiology

Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture

(2018) Nathalia M. de Vasconcelos et al.   CELL DEATH AND DIFFERENTIATION

ZBP1: Innate Sensor Regulating Cell Death and Inflammation

(2018) Teneema Kuriakose et al.   TRENDS IN IMMUNOLOGY

Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection

(2018) Joseph Sarhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death

(2018) Pontus Orning et al.   SCIENCE

RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense

(2017) Lance W. Peterson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death

(2017) Sannula Kesavardhana et al.   JOURNAL OF EXPERIMENTAL MEDICINE

DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death

(2016) Roshan J. Thapa et al.   Cell Host & Microbe

RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus

(2016) Shoko Nogusa et al.   Cell Host & Microbe

The intersection of cell death and inflammasome activation

(2016) James E. Vince et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cell-Extrinsic TNF Collaborates with TRIF Signaling To PromoteYersinia-Induced Apoptosis

(2016) Lance W. Peterson et al.   JOURNAL OF IMMUNOLOGY

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

(2016) Xing Liu et al.   NATURE

RIPK1 inhibits ZBP1-driven necroptosis during development

(2016) Kim Newton et al.   NATURE

RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation

(2016) Juan Lin et al.   NATURE

GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes

(2016) Robin A. Aglietti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

Toll-like receptor signalling through macromolecular protein complexes

(2015) Clare E. Bryant et al.   MOLECULAR IMMUNOLOGY

Receptor-Interacting Protein Homotypic Interaction Motif-Dependent Control of NF- B Activation via the DNA-Dependent Activator of IFN Regulatory Factors

(2014) W. J. Kaiser et al.   JOURNAL OF IMMUNOLOGY

Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF- B and MAPK signaling

(2014) N. H. Philip et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death

(2014) D. Weng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DAI/ZBP1/DLM-1 Complexes with RIP3 to Mediate Virus-Induced Programmed Necrosis that Is Targeted by Murine Cytomegalovirus vIRA

(2012) Jason W. Upton et al.   Cell Host & Microbe

Serine/threonine acetylation of TGF -activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling

(2012) N. Paquette et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

(2011) Ivan Zanoni et al.   CELL

DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-κB

(2009) Manuele Rebsamen et al.   EMBO REPORTS

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

(2008) Jonathan C Kagan et al.   NATURE IMMUNOLOGY