Human iNSC-derived brain organoid model of lysosomal storage disorder in Niemann–Pick disease type C
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Human iNSC-derived brain organoid model of lysosomal storage disorder in Niemann–Pick disease type C
Authors
Keywords
-
Journal
Cell Death & Disease
Volume 11, Issue 12, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-12-12
DOI
10.1038/s41419-020-03262-7
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Correction of Niemann-Pick type C1 trafficking and activity with the histone deacetylase inhibitor valproic acid
- (2020) Kanagaraj Subramanian et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Modeling G2019S-LRRK2 Sporadic Parkinson's Disease in 3D Midbrain Organoids
- (2019) Hongwon Kim et al. Stem Cell Reports
- NPC1 regulates ER contacts with endocytic organelles to mediate cholesterol egress
- (2019) D. Höglinger et al. Nature Communications
- Single-Factor SOX2 Mediates Direct Neural Reprogramming of Human Mesenchymal Stem Cells via Transfection of In Vitro Transcribed mRNA
- (2018) Bo-Eun Kim et al. CELL TRANSPLANTATION
- APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types
- (2018) Yuan-Ta Lin et al. NEURON
- Consensus clinical management guidelines for Niemann-Pick disease type C
- (2018) Tarekegn Geberhiwot et al. Orphanet Journal of Rare Diseases
- Intrathecal 2-hydroxypropyl-β-cyclodextrin decreases neurological disease progression in Niemann-Pick disease, type C1: a non-randomised, open-label, phase 1–2 trial
- (2017) Daniel S Ory et al. LANCET
- The use of brain organoids to investigate neural development and disease
- (2017) Elizabeth Di Lullo et al. NATURE REVIEWS NEUROSCIENCE
- Generation of patient specific human neural stem cells from Niemann-Pick disease type C patient-derived fibroblasts
- (2017) Eun-Ah Sung et al. Oncotarget
- Visualization of a short-range Wnt gradient in the intestinal stem-cell niche
- (2016) Henner F. Farin et al. NATURE
- Erratum: Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis
- (2016) Minoru Takasato et al. NATURE
- Retinal Organoids from Pluripotent Stem Cells Efficiently Recapitulate Retinogenesis
- (2016) Manuela Völkner et al. Stem Cell Reports
- Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer’s Disease Phenotypes
- (2016) Waseem K. Raja et al. PLoS One
- Rapid and Efficient Direct Conversion of Human Adult Somatic Cells into Neural Stem Cells by HMGA2/let-7b
- (2015) Kyung-Rok Yu et al. Cell Reports
- Neural progenitors, neurogenesis and the evolution of the neocortex
- (2014) M. Florio et al. DEVELOPMENT
- Generation of cerebral organoids from human pluripotent stem cells
- (2014) Madeline A Lancaster et al. Nature Protocols
- Organogenesis in a dish: Modeling development and disease using organoid technologies
- (2014) M. A. Lancaster et al. SCIENCE
- Cerebral organoids model human brain development and microcephaly
- (2013) Madeline A. Lancaster et al. NATURE
- Toward a 3D model of human brain development for studying gene/environment interactions
- (2013) Helena T Hogberg et al. Stem Cell Research & Therapy
- Autophagy in lysosomal storage disorders
- (2012) Andrew P. Lieberman et al. Autophagy
- Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts
- (2011) N. H. Pipalia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Niemann-Pick type C disease: molecular mechanisms and potential therapeutic approaches
- (2010) Anton I. Rosenbaum et al. JOURNAL OF NEUROCHEMISTRY
- Niemann-Pick C1 Functions Independently of Niemann-Pick C2 in the Initial Stage of Retrograde Transport of Membrane-impermeable Lysosomal Cargo
- (2009) Stephen D. B. Goldman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Niemann-Pick C1 Functions in Regulating Lysosomal Amine Content
- (2008) Allyn M. Kaufmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Niemann-Pick Type C1 I1061T Mutant Encodes a Functional Protein That Is Selected for Endoplasmic Reticulum-associated Degradation Due to Protein Misfolding
- (2008) Mark E. Gelsthorpe et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now