Histone deacetylase 2 regulates ULK1 mediated pyroptosis during acute liver failure by the K68 acetylation site

Incidence and Mortality of Acute on Chronic Liver Failure using Two Definitions in Patients with Compensated Cirrhosis

(2019) Nadim Mahmud et al.   HEPATOLOGY

Regulation of Acetylation in High Mobility Group Protein B1 Cytosol Translocation

(2019) Yao Wang et al.   DNA AND CELL BIOLOGY

Histone deacetylases and acetylated histone H3 are involved in the process of hepatitis B virus DNA replication

(2019) Di Zhang et al.   LIFE SCIENCES

ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97

(2019) Bo Wang et al.   MOLECULAR CELL

Acute liver failure

(2019) R Todd Stravitz et al.   LANCET

Liver Transplantation for Acute Liver Failure

(2018) Raquel Olivo et al.   Clinics in Liver Disease

The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages

(2018) Zsolt Czimmerer et al.   IMMUNITY

Gasdermin D plays a key role as a pyroptosis executor of non-alcoholic steatohepatitis in humans and mice

(2018) Bing Xu et al.   JOURNAL OF HEPATOLOGY

Hepatocyte-specific deletion of IL1-RI attenuates liver injury by blocking IL-1 driven autoinflammation

(2018) Nadine Gehrke et al.   JOURNAL OF HEPATOLOGY

Globular adiponectin protects hepatocytes from tunicamycin-induced cell death via modulation of the inflammasome and heme oxygenase-1 induction

(2018) Amrita Khakurel et al.   PHARMACOLOGICAL RESEARCH

DAMPs and sterile inflammation in drug hepatotoxicity

(2018) Runkuan Yang et al.   Hepatology International

Benzo[a]pyrene Induces Autophagic and Pyroptotic Death Simultaneously in HL-7702 Human Normal Liver Cells

(2017) Li Yuan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure

(2017) Julia Wendon et al.   JOURNAL OF HEPATOLOGY

Cutting Edge: Eosinophils Undergo Caspase-1–Mediated Pyroptosis in Response to Necrotic Liver Cells

(2017) Daphne Palacios-Macapagal et al.   JOURNAL OF IMMUNOLOGY

Histone modifications: A review about the presence of this epigenetic phenomenon in carcinogenesis

(2017) Emanuely Silva Chrun et al.   PATHOLOGY RESEARCH AND PRACTICE

Inflammasomes in Liver Fibrosis

(2017) Fernando Alegre et al.   SEMINARS IN LIVER DISEASE

Defects in MAP1S-mediated autophagy turnover of fibronectin cause renal fibrosis

(2016) Guibin Xu et al.   Aging-US

SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages

(2016) Min-Ji Kim et al.   Autophagy

CdSe/ZnS quantum dots induce hepatocyte pyroptosis and liver inflammation via NLRP3 inflammasome activation

(2016) Yonghui Lu et al.   BIOMATERIALS

Gut microbiome and liver diseases

(2016) Herbert Tilg et al.   GUT

Pore-forming activity and structural autoinhibition of the gasdermin family

(2016) Jingjin Ding et al.   NATURE

Experimental models of hepatotoxicity related to acute liver failure

(2016) Michaël Maes et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mechanism and Regulation of NLRP3 Inflammasome Activation

(2016) Yuan He et al.   TRENDS IN BIOCHEMICAL SCIENCES

Hepatitis C Virus Infection of Cultured Human Hepatoma Cells Causes Apoptosis and Pyroptosis in Both Infected and Bystander Cells

(2016) H. M. Kofahi et al.   Scientific Reports

Potassium Bisperoxo(1,10-phenanthroline)oxovanadate (bpV(phen)) Induces Apoptosis and Pyroptosis and Disrupts the P62-HDAC6 Protein Interaction to Suppress the Acetylated Microtubule-dependent Degradation of Autophagosomes

(2015) Qi Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy.

(2015) Katy J. Petherick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heatstroke induces liver injury via IL-1β and HMGB1-induced pyroptosis

(2015) Yan Geng et al.   JOURNAL OF HEPATOLOGY

Salvianolic acid A attenuates TNF-α- and d-GalN-induced ER stress-mediated and mitochondrial-dependent apoptosis by modulating Bax/Bcl-2 ratio and calcium release in hepatocyte LO2 cells

(2015) Xiaojing Yan et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

ER stress induces NLRP3 inflammasome activation and hepatocyte death

(2015) C Lebeaupin et al.   Cell Death & Disease

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

Hepatitis B flares in chronic hepatitis B: Pathogenesis, natural course, and management

(2014) Ming-Ling Chang et al.   JOURNAL OF HEPATOLOGY

Cell Death-Associated Molecular-Pattern Molecules: Inflammatory Signaling and Control

(2014) Beatriz Sangiuliano et al.   MEDIATORS OF INFLAMMATION

Erasers of Histone Acetylation: The Histone Deacetylase Enzymes

(2014) E. Seto et al.   Cold Spring Harbor Perspectives in Biology

Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation

(2014) Nina Van Opdenbosch et al.   Nature Communications

Involvement of Inflammasome Activation in Lipopolysaccharide-induced Mice Depressive-like Behaviors

(2013) Yi Zhang et al.   CNS Neuroscience & Therapeutics

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

(2012) Chong-Shan Shi et al.   NATURE IMMUNOLOGY

GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy

(2012) S.-Y. Lin et al.   SCIENCE

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Caspase-1 Inhibitor Prevents Neurogenic Pulmonary Edema After Subarachnoid Hemorrhage in Mice

(2009) Hidenori Suzuki et al.   STROKE

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE