Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation
Authors
Keywords
-
Journal
Cell Death & Disease
Volume 11, Issue 12, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-12-10
DOI
10.1038/s41419-020-03174-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module
- (2020) Laura Di Magno et al. Cell Reports
- Current Options for Third-Line and Beyond Treatment of Metastatic Colorectal Cancer. Spanish TTD Group Expert Opinion
- (2020) Ana Fernández-Montes et al. Clinical Colorectal Cancer
- Loss of HAT1 expression confers BRAFV600E inhibitor resistance to melanoma cells by activating MAPK signaling via IGF1R
- (2020) Suresh Bugide et al. Oncogenesis
- Inhibition of Eukaryotic Translation Initiation Factor 5A (eIF5A) Hypusination Suppress p53 Translation and Alters the Association of eIF5A to the Ribosomes
- (2020) Marianna Martella et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis
- (2019) Shuo Liu et al. CELL
- A Simplified Genomic Profiling Approach Predicts Outcome in Metastatic Colorectal Cancer
- (2019) Carlo Capalbo et al. Cancers
- Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence
- (2019) Hanlin Zhang et al. MOLECULAR CELL
- Suppression of Ribosomal Pausing by eIF5A Is Necessary to Maintain the Fidelity of Start Codon Selection
- (2019) Hema Manjunath et al. Cell Reports
- EIF5A1 promotes epithelial ovarian cancer proliferation and progression
- (2018) Jing Zhang et al. BIOMEDICINE & PHARMACOTHERAPY
- KRAS Oncoprotein Expression Is Regulated by a Self-Governing eIF5A-PEAK1 Feed-Forward Regulatory Loop
- (2018) Ken Fujimura et al. CANCER RESEARCH
- Hypusine, a polyamine-derived amino acid critical for eukaryotic translation
- (2018) Myung Hee Park et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cancer pharmacoprevention: Targeting polyamine metabolism to manage risk factors for colon cancer
- (2018) Eugene W. Gerner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Roles of polyamines in translation
- (2018) Thomas E. Dever et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- eIF5A Functions Globally in Translation Elongation and Termination
- (2017) Anthony P. Schuller et al. MOLECULAR CELL
- eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequences
- (2017) Vicent Pelechano et al. NUCLEIC ACIDS RESEARCH
- Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma
- (2017) Sonia Coni et al. Scientific Reports
- Global patterns and trends in colorectal cancer incidence and mortality
- (2016) Melina Arnold et al. GUT
- BPTF is required for c-MYC transcriptional activity and in vivo tumorigenesis
- (2016) Laia Richart et al. Nature Communications
- The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint
- (2016) Laura Di Magno et al. Oncotarget
- The translation factor eIF5A and human cancer
- (2015) Michael B. Mathews et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Non-canonical Hedgehog/AMPK-Mediated Control of Polyamine Metabolism Supports Neuronal and Medulloblastoma Cell Growth
- (2015) Davide D’Amico et al. DEVELOPMENTAL CELL
- Targeting Translation Initiation Bypasses Signaling Crosstalk Mechanisms That Maintain High MYC Levels in Colorectal Cancer
- (2015) A. Wiegering et al. Cancer Discovery
- Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth
- (2014) Laura Di Magno et al. CELL CYCLE
- Deoxyhypusine synthase (DHPS) inhibitor GC7 induces p21/Rb-mediated inhibition of tumor cell growth and DHPS expression correlates with poor prognosis in neuroblastoma patients
- (2014) Andrea Bandino et al. CELLULAR ONCOLOGY
- Overexpression of CK20, MAP3K8 and EIF5A correlates with poor prognosis in early-onset colorectal cancer patients
- (2013) Berrin Tunca et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- eIF5A Promotes Translation of Polyproline Motifs
- (2013) Erik Gutierrez et al. MOLECULAR CELL
- Epigenetic and genetic features of 24 colon cancer cell lines
- (2013) D Ahmed et al. Oncogenesis
- The Role of Polyamines in Supporting Growth of Mammalian Cells Is Mediated through Their Requirement for Translation Initiation and Elongation
- (2010) Guy Landau et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting Ornithine Decarboxylase Impairs Development of MYCN-Amplified Neuroblastoma
- (2009) R. J. Rounbehler et al. CANCER RESEARCH
- Polyamines Regulate c-Myc Translation through Chk2-dependent HuR Phosphorylation
- (2009) Lan Liu et al. MOLECULAR BIOLOGY OF THE CELL
- Molecular Basis of Colorectal Cancer
- (2009) Sanford D. Markowitz et al. NEW ENGLAND JOURNAL OF MEDICINE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started