Development of DNA Vaccine Targeting E6 and E7 Proteins of Human Papillomavirus 16 (HPV16) and HPV18 for Immunotherapy in Combination with Recombinant Vaccinia Boost and PD-1 Antibody

Potential of Pembrolizumab in Metastatic or Recurrent Head and Neck Cancer: Evidence to Date

(2020) Michael G McCusker et al.   OncoTargets and Therapy

High-Risk HPV Oncoproteins and PD-1/PD-L1 Interplay in Human Cervical Cancer: Recent Evidence and Future Directions

(2020) Soumaya Allouch et al.   Frontiers in Oncology

PD-1/PD-L1 Inhibitors in Cervical Cancer

(2019) Yuncong Liu et al.   Frontiers in Pharmacology

Epidemiology and burden of HPV-related disease

(2018) Beatriz Serrano et al.   BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY

Therapeutic DNA Vaccines for Human Papillomavirus and Associated Diseases

(2018) Max A. Cheng et al.   HUMAN GENE THERAPY

Measuring multiple parameters of CD8+ tumor-infiltrating lymphocytes in human cancers by image analysis

(2018) Keith E. Steele et al.   Journal for ImmunoTherapy of Cancer

Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods

(2018) J. Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

The Immune Epitope Database (IEDB): 2018 update

(2018) Randi Vita et al.   NUCLEIC ACIDS RESEARCH

Epithelial boost enhances antigen expression by vaccinia virus for the generation of potent CD8+ T cell-mediated antitumor immunity following DNA priming vaccination

(2018) Jin Qiu et al.   VIROLOGY

Increased expression of PD-L1 by the human papillomavirus 16 E7 oncoprotein inhibits anticancer immunity

(2017) Chaoqi Liu et al.   Molecular Medicine Reports

Characterization of HPV18 E6-specific T cell responses and establishment of HPV18 E6-expressing tumor model

(2017) Ying Ma et al.   VACCINE

The current state of therapeutic and T cell-based vaccines against human papillomaviruses

(2017) Andrew Yang et al.   VIRUS RESEARCH

Facilitating T Cell Infiltration in Tumor Microenvironment Overcomes Resistance to PD-L1 Blockade

(2016) Haidong Tang et al.   CANCER CELL

Identification of the murine H-2Db and human HLA-A*0201 MHC class I-restricted HPV6 E7-specific cytotoxic T lymphocyte epitopes

(2016) Shiwen Peng et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

A pilot study of pNGVL4a-CRT/E7(detox) for the treatment of patients with HPV16 + cervical intraepithelial neoplasia 2/3 (CIN2/3)

(2016) Ronald D. Alvarez et al.   GYNECOLOGIC ONCOLOGY

Elevated Expression of Programmed Death-1 and Programmed Death Ligand-1 Negatively Regulates Immune Response against Cervical Cancer Cells

(2016) Zhifang Chen et al.   MEDIATORS OF INFLAMMATION

Optimization of heterologous DNA-prime, protein boost regimens and site of vaccination to enhance therapeutic immunity against human papillomavirus-associated disease

(2016) Shiwen Peng et al.   Cell and Bioscience

HPV Associated Head and Neck Cancer

(2016) Tara Spence et al.   Cancers

Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential

(2015) Padmanee Sharma et al.   CELL

Local HPV Recombinant Vaccinia Boost Following Priming with an HPV DNA Vaccine Enhances Local HPV-Specific CD8+ T-cell-Mediated Tumor Control in the Genital Tract

(2015) Y.-Y. Sun et al.   CLINICAL CANCER RESEARCH

Epidemiology of Human Papillomavirus–Positive Head and Neck Squamous Cell Carcinoma

(2015) Maura L. Gillison et al.   JOURNAL OF CLINICAL ONCOLOGY

Enhanced expression of PD L1 in cervical intraepithelial neoplasia and cervical cancers

(2015) Louisa Mezache et al.   MODERN PATHOLOGY

Human papillomavirus molecular biology and disease association

(2015) John Doorbar et al.   REVIEWS IN MEDICAL VIROLOGY

PD-1 or PD-L1 Blockade Restores Antitumor Efficacy Following SSX2 Epitope-Modified DNA Vaccine Immunization

(2015) B. T. Rekoske et al.   Cancer Immunology Research

A Novel Mutant of Human Papillomavirus Type 18 E6E7 Fusion Gene and its Transforming Activity

(2014) Zhi-Xiang Zhou et al.   Asian Pacific Journal of Cancer Prevention

Preclinical Evidence That PD1 Blockade Cooperates with Cancer Vaccine TEGVAX to Elicit Regression of Established Tumors

(2014) J. Fu et al.   CANCER RESEARCH

Intramuscular Therapeutic Vaccination Targeting HPV16 Induces T Cell Responses That Localize in Mucosal Lesions

(2014) L. Maldonado et al.   Science Translational Medicine

A fast Peptide Match service for UniProt Knowledgebase

(2013) Chuming Chen et al.   BIOINFORMATICS

Suppression of breast tumor growth by DNA vaccination against phosphatase of regenerating liver 3

(2013) J Lv et al.   GENE THERAPY

Papillomavirus E6 oncoproteins

(2013) Scott B. Vande Pol et al.   VIROLOGY

The role of HPV in head and neck cancer and review of the HPV vaccine

(2011) Gypsyamber D'Souza et al.   PREVENTIVE MEDICINE

Molecular mechanisms of cervical carcinogenesis by high-risk human papillomaviruses: novel functions of E6 and E7 oncoproteins

(2009) Takashi Yugawa et al.   REVIEWS IN MEDICAL VIROLOGY

A Phase I Trial of a Human Papillomavirus DNA Vaccine for HPV16+ Cervical Intraepithelial Neoplasia 2/3

(2008) C. L. Trimble et al.   CLINICAL CANCER RESEARCH

DNA vaccines: ready for prime time?

(2008) Michele A. Kutzler et al.   NATURE REVIEWS GENETICS

Deletion of the PDZ motif of HPV16 E6 preventing immortalization and anchorage-independent growth in human tonsil epithelial cells

(2007) William C. Spanos et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK