The ANGPTL8 rs2278426 (C/T) Polymorphism Is Associated with Prediabetes and Type 2 Diabetes in a Han Chinese Population in Hebei Province

Association of ANGPTL8 (Betatrophin) Gene Variants with Components of Metabolic Syndrome in Arab Adults

(2020) Amal Alenad et al.   Scientific Reports

UCP2–866G/A Polymorphism is Associated with Prediabetes and Type 2 Diabetes

(2020) Guangsen Hou et al.   ARCHIVES OF MEDICAL RESEARCH

Interaction between endothelial nitric oxide synthase rs1799983, cholesteryl ester-transfer protein rs708272 and angiopoietin-like protein 8 rs2278426 gene variants highly elevates the risk of type 2 diabetes mellitus and cardiovascular disease

(2018) Dalia El-Lebedy   Cardiovascular Diabetology

High frequency of type 2 diabetes and impaired glucose tolerance in Japanese subjects with the angiopoietin-like protein 8 R59W variant

(2018) Jianhui Liu et al.   Journal of Clinical Lipidology

Association between rs2278426 (C/T) and rs892066 (C/G) variants of ANGPTL8 (betatrophin) and susceptibility to type2 diabetes mellitus

(2018) Hassan Ghasemi et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Visualizing the regulatory role of Angiopoietin-like protein 8 (ANGPTL8) in glucose and lipid metabolic pathways

(2017) Amnah Siddiqa et al.   GENOMICS

Small Ubiquitin-Like Modifier 4 (SUMO4) Gene M55V Polymorphism and Type 2 Diabetes Mellitus: A Meta-analysis Including 6,823 Subjects

(2017) Yan-yan Li et al.   Frontiers in Endocrinology

Higher serum betatrophin level in type 2 diabetes subjects is associated with urinary albumin excretion and renal function

(2016) Chang-Chiang Chen et al.   Cardiovascular Diabetology

ANGPTL8/betatrophin alleviates insulin resistance via the Akt-GSK3β or Akt-FoxO1 pathway in HepG2 cells

(2016) Xing Rong Guo et al.   EXPERIMENTAL CELL RESEARCH

Targeting pancreatic expressed PAX genes for the treatment of diabetes mellitus and pancreatic neuroendocrine tumors

(2016) Alejandro Martin-Montalvo et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Positive Association Between Betatrophin and Diabetic Retinopathy Risk in Type 2 Diabetes Patients

(2016) Y.-Y. Wang et al.   HORMONE AND METABOLIC RESEARCH

Circulating betatrophin in healthy control and type 2 diabetic subjects and its association with metabolic parameters

(2016) Nasser M. Al-Daghri et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

ANGPTL8/Betatrophin R59W variant is associated with higher glucose level in non-diabetic Arabs living in Kuwaits

(2016) Mohamed Abu-Farha et al.   Lipids in Health and Disease

The Arg59Trp variant in ANGPTL8 (betatrophin) is associated with total and HDL-cholesterol in American Indians and Mexican Americans and differentially affects cleavage of ANGPTL3

(2016) Robert L. Hanson et al.   MOLECULAR GENETICS AND METABOLISM

The Effects of Serum ANGPTL8/betatrophin on the Risk of Developing the Metabolic Syndrome – A Prospective Study

(2016) Haoyu Wang et al.   Scientific Reports

Circulating ANGPTL8/Betatrophin Is Increased in Obesity and Reduced after Exercise Training

(2016) Mohamed Abu-Farha et al.   PLoS One

In vivo targeted delivery of ANGPTL8 gene for beta cell regeneration in rats

(2015) Jiaxi Chen et al.   DIABETOLOGIA

Circulating Betatrophin Levels Are Increased in Patients With Type 2 Diabetes and Associated With Insulin Resistance

(2015) Xi Chen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Association of the angiopoietin-like protein 8 rs2278426 polymorphism and several environmental factors with serum lipid levels

(2015) TAO GUO et al.   Molecular Medicine Reports

Pax4 acts as a key player in pancreas development and plasticity

(2015) Tiziana Napolitano et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Betatrophin Acts as a Diagnostic Biomarker in Type 2 Diabetes Mellitus and Is Negatively Associated with HDL-Cholesterol

(2015) Min Yi et al.   International Journal of Endocrinology

Higher plasma betatrophin/ANGPTL8 level in Type 2 Diabetes subjects does not correlate with blood glucose or insulin resistance

(2015) Mohamed Abu-Farha et al.   Scientific Reports

The Association between HMGA1 rs146052672 Variant and Type 2 Diabetes: A Transethnic Meta-Analysis

(2015) Aida Bianco et al.   PLoS One

A dual role of lipasin (betatrophin) in lipid metabolism and glucose homeostasis: consensus and controversy

(2014) Ren Zhang et al.   Cardiovascular Diabetology

Pax genes: regulators of lineage specification and progenitor cell maintenance

(2014) J. A. Blake et al.   DEVELOPMENT

Emerging Regulation and Function of Betatrophin

(2014) Yi-Hsin Tseng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

BMI and waist circumference are associated with impaired glucose metabolism and type 2 diabetes in normal weight Chinese adults

(2014) Shengxu Li et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

A Novel Arginine to Tryptophan (R144W) Mutation in Troponin T (cTnT) Gene in an Indian Multigenerational Family with Dilated Cardiomyopathy (FDCM)

(2014) Deepa Selvi Rani et al.   PLoS One

The ability of an arginine to tryptophan substitution in Saccharomyces cerevisiae tRNA nucleotidyltransferase to alleviate a temperature-sensitive phenotype suggests a role for motif C in active site organization

(2013) Mark E. Goring et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The Origins and Drivers of Insulin Resistance

(2013) Andrew M.F. Johnson et al.   CELL

Betatrophin Fuels β Cell Proliferation: First Step toward Regenerative Therapy?

(2013) Heiko Lickert   Cell Metabolism

Direct Autocrine Action of Insulin on  -Cells: Does It Make Physiological Sense?

(2013) C. J. Rhodes et al.   DIABETES

Incretin Action in the Pancreas: Potential Promise, Possible Perils, and Pathological Pitfalls

(2013) D. J. Drucker   DIABETES

Prevalence and Control of Diabetes in Chinese Adults

(2013) Yu Xu   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Evidence That an HMGA1 Gene Variant Associates with Type 2 Diabetes, Body Mass Index, and High-Density Lipoprotein Cholesterol in a Hispanic-American Population

(2013) Clive R. Pullinger et al.   Metabolic Syndrome and Related Disorders

Betatrophin—inducing β-cell expansion to treat diabetes mellitus?

(2013) Elisabeth Kugelberg   Nature Reviews Endocrinology

Identification of RIFL, a novel adipocyte-enriched insulin target gene with a role in lipid metabolism

(2012) Gang Ren et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels

(2012) Ren Zhang   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lipasin, thermoregulated in brown fat, is a novel but atypical member of the angiopoietin-like protein family

(2012) Zhiyao Fu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Diabetes Mellitus and the β Cell: The Last Ten Years

(2012) Frances M. Ashcroft et al.   CELL

Atypical angiopoietin-like protein that regulates ANGPTL3

(2012) F. Quagliarini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perplexing Pax: From puzzle to paradigm

(2008) Judith A. Blake et al.   DEVELOPMENTAL DYNAMICS