Pseudotyping Lentiviral Vectors: When the Clothes Make the Virus

Lentiviral gene therapy for X-linked chronic granulomatous disease

(2020) Donald B. Kohn et al.   NATURE MEDICINE

Nuclear pore blockade reveals that HIV-1 completes reverse transcription and uncoating in the nucleus

(2020) Adarsh Dharan et al.   Nature Microbiology

Tropism of the Chikungunya Virus

(2019) Giulia Matusali et al.   Viruses-Basel

Differential role for phosphorylation in alternative polyadenylation function versus nuclear import of SR-like protein CPSF6

(2019) Sooin Jang et al.   NUCLEIC ACIDS RESEARCH

A lipid-based partitioning mechanism for selective incorporation of proteins into membranes of HIV particles

(2019) Prabuddha Sengupta et al.   NATURE CELL BIOLOGY

Conformational changes in Chikungunya virus E2 protein upon heparan sulfate receptor binding explain mechanism of E2–E1 dissociation during viral entry

(2019) Bibekananda Sahoo et al.   BIOSCIENCE REPORTS

Successful engraftment of gene-corrected hematopoietic stem cells in non-conditioned patients with Fanconi anemia

(2019) Paula Río et al.   NATURE MEDICINE

Macropinocytosis dependent entry of Chikungunya virus into human muscle cells

(2019) Ching Hua et al.   PLoS Neglected Tropical Diseases

Prohibitin (PHB) expression is associated with aggressiveness in DLBCL and flavagline-mediated inhibition of cytoplasmic PHB functions induces anti-tumor effects

(2019) Hafidha Bentayeb et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Single HIV-1 Imaging Reveals Progression of Infection through CA-Dependent Steps of Docking at the Nuclear Pore, Uncoating, and Nuclear Transport

(2018) Ashwanth C. Francis et al.   Cell Host & Microbe

Mxra8 is a receptor for multiple arthritogenic alphaviruses

(2018) Rong Zhang et al.   NATURE

Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia

(2018) Alexis A. Thompson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gene therapy comes of age

(2018) Cynthia E. Dunbar et al.   SCIENCE

Metabotropic glutamate receptor subtype 2 is a cellular receptor for rabies virus

(2018) Jinliang Wang et al.   PLoS Pathogens

Consensus approach for the management of severe combined immune deficiency caused by adenosine deaminase deficiency

(2018) Donald B. Kohn et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lentiviral transduction of mammalian cells for fast, scalable and high-level production of soluble and membrane proteins

(2018) Jonathan Elegheert et al.   Nature Protocols

The Range of Neurological Complications in Chikungunya Fever

(2017) T. Cerny et al.   Neurocritical Care

Gene Therapy in a Patient with Sickle Cell Disease

(2017) Jean-Antoine Ribeil et al.   NEW ENGLAND JOURNAL OF MEDICINE

CAR T-Cell Therapy: Progress and Prospects

(2017) Olivia Wilkins et al.   Human Gene Therapy Methods

Dynamics and regulation of nuclear import and nuclear movements of HIV-1 complexes

(2017) Ryan C. Burdick et al.   PLoS Pathogens

Efficient Ex Vivo Engineering and Expansion of Highly Purified Human Hematopoietic Stem and Progenitor Cell Populations for Gene Therapy

(2017) Erika Zonari et al.   Stem Cell Reports

Glycosylphosphatidylinositol Anchor Deficiency Attenuates the Production of Infectious HIV-1 and Renders Virions Sensitive to Complement Attack

(2016) Tohti Amet et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

The benefits of integration

(2016) A. Ciuffi   CLINICAL MICROBIOLOGY AND INFECTION

Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial

(2016) Maria Sessa et al.   LANCET

Raft-based interactions of gangliosides with a GPI-anchored receptor

(2016) Naoko Komura et al.   Nature Chemical Biology

Getting to the Outer Leaflet: Physiology of Phosphatidylserine Exposure at the Plasma Membrane

(2016) Edouard M. Bevers et al.   PHYSIOLOGICAL REVIEWS

Mechanism of membrane fusion induced by vesicular stomatitis virus G protein

(2016) Irene S. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lentiviral hematopoietic stem cell gene therapy for X-linked severe combined immunodeficiency

(2016) Suk See De Ravin et al.   Science Translational Medicine

Measles Virus Fusion Protein: Structure, Function and Inhibition

(2016) Philippe Plattet et al.   Viruses-Basel

Transcriptional, epigenetic and retroviral signatures identify regulatory regions involved in hematopoietic lineage commitment

(2016) Oriana Romano et al.   Scientific Reports

Ophthalmologic aspects of chikungunya infection

(2016) Dayron F. Martínez-Pulgarín et al.   Travel Medicine and Infectious Disease

Receptor-Targeted Nipah Virus Glycoproteins Improve Cell-Type Selective Gene Delivery and Reveal a Preference for Membrane-Proximal Cell Attachment

(2016) Ruben R. Bender et al.   PLoS Pathogens

Rabies Internalizes into Primary Peripheral Neurons via Clathrin Coated Pits and Requires Fusion at the Cell Body

(2016) Silvia Piccinotti et al.   PLoS Pathogens

Prohibitin 2: At a communications crossroads

(2015) Alberto Bavelloni et al.   IUBMB LIFE

Liver-directed lentiviral gene therapy in a dog model of hemophilia B

(2015) Alessio Cantore et al.   Science Translational Medicine

Early Events in Chikungunya Virus Infection—From Virus CellBinding to Membrane Fusion

(2015) Mareike van Duijl-Richter et al.   Viruses-Basel

Expressed Glycosylphosphatidylinositol-Anchored Horseradish Peroxidase Identifies Co-Clustering Molecules in Individual Lipid Raft Domains

(2014) Arisa Miyagawa-Yamaguchi et al.   PLoS One

Gene Therapy for Wiskott-Aldrich Syndrome--Long-Term Efficacy and Genotoxicity

(2014) C. J. Braun et al.   Science Translational Medicine

Chikungunya fever: Epidemiology, clinical syndrome, pathogenesis and therapy

(2013) Simon-Djamel Thiberville et al.   ANTIVIRAL RESEARCH

Gene therapy on the move

(2013) Kerstin B. Kaufmann et al.   EMBO Molecular Medicine

History of gene therapy

(2013) Thomas Wirth et al.   GENE

Characterization of a third generation lentiviral vector pseudotyped with Nipah virus envelope proteins for endothelial cell transduction

(2013) S R Witting et al.   GENE THERAPY

Alphavirus Genome Delivery Occurs Directly at the Plasma Membrane in a Time- and Temperature-Dependent Process

(2013) R. Vancini et al.   JOURNAL OF VIROLOGY

The Role of E3 in pH Protection during Alphavirus Assembly and Exit

(2013) O. Uchime et al.   JOURNAL OF VIROLOGY

Crystal Structure of the Nipah Virus Phosphoprotein Tetramerization Domain

(2013) J. F. Bruhn et al.   JOURNAL OF VIROLOGY

Laminin Receptor 37/67LR Regulates Adhesion and Proliferation of Normal Human Intestinal Epithelial Cells

(2013) Taoufik Khalfaoui et al.   PLoS One

LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus

(2013) D. Finkelshtein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm

(2013) Alberto De Iaco et al.   Retrovirology

Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses

(2013) D. Gao et al.   SCIENCE

Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome

(2013) A. Aiuti et al.   SCIENCE

Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy

(2013) A. Biffi et al.   SCIENCE

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

HIV-1 Assembly, Budding, and Maturation

(2013) W. I. Sundquist et al.   Cold Spring Harbor Perspectives in Medicine

Mosquito Cellular Factors and Functions in Mediating the Infectious entry of Chikungunya Virus

(2013) Regina Ching Hua Lee et al.   PLoS Neglected Tropical Diseases

Hyperfunctional coagulation factor IX improves the efficacy of gene therapy in hemophilic mice

(2012) A. Cantore et al.   BLOOD

Targeted lentiviral vectors pseudotyped with the Tupaia paramyxovirus glycoproteins

(2012) T Enkirch et al.   GENE THERAPY

Identification of prohibitin as a Chikungunya virus receptor protein

(2012) Phitchayapak Wintachai et al.   JOURNAL OF MEDICAL VIROLOGY

The Alphavirus E3 Glycoprotein Functions in a Clade-Specific Manner

(2012) A. J. Snyder et al.   JOURNAL OF VIROLOGY

Nipah Virus Envelope-Pseudotyped Lentiviruses Efficiently Target ephrinB2-Positive Stem Cell Populations In Vitro and Bypass the Liver Sink When Administered In Vivo

(2012) K. Palomares et al.   JOURNAL OF VIROLOGY

FLASH assembly of TALENs for high-throughput genome editing

(2012) Deepak Reyon et al.   NATURE BIOTECHNOLOGY

Measles Virus Glycoprotein-Based Lentiviral Targeting Vectors That Avoid Neutralizing Antibodies

(2012) Sabrina Kneissl et al.   PLoS One

Molecular and Cellular Aspects of Rhabdovirus Entry

(2012) Aurélie A. V. Albertini et al.   Viruses-Basel

Paramyxovirus Fusion and Entry: Multiple Paths to a Common End

(2012) Andres Chang et al.   Viruses-Basel

Natural Resistance-Associated Macrophage Protein Is a Cellular Receptor for Sindbis Virus in Both Insect and Mammalian Hosts

(2011) Patrick P. Rose et al.   Cell Host & Microbe

DARPins: An Efficient Targeting Domain for Lentiviral Vectors

(2011) Robert C Münch et al.   MOLECULAR THERAPY

Atomic-level modelling of the HIV capsid

(2011) Owen Pornillos et al.   NATURE

Adherens junction protein nectin-4 is the epithelial receptor for measles virus

(2011) Michael D. Mühlebach et al.   NATURE

Long-Term Persistence of a Polyclonal T Cell Repertoire After Gene Therapy for X-Linked Severe Combined Immunodeficiency

(2011) H. B. Gaspar et al.   Science Translational Medicine

HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency

(2011) Torsten Schaller et al.   PLoS Pathogens

Tumor Cell Marker PVRL4 (Nectin 4) Is an Epithelial Cell Receptor for Measles Virus

(2011) Ryan S. Noyce et al.   PLoS Pathogens

Nectin 4 Overexpression in Ovarian Cancer Tissues and Serum

(2010) Melissa S. DeRycke et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

High-definition mapping of retroviral integration sites identifies active regulatory elements in human multipotent hematopoietic progenitors

(2010) C. Cattoglio et al.   BLOOD

Effective in vivo and ex vivogene transfer to intestinal mucosa by VSV-G-pseudotyped lentiviral vectors

(2010) Hiroshi Matsumoto et al.   BMC GASTROENTEROLOGY

Flexible Use of Nuclear Import Pathways by HIV-1

(2010) KyeongEun Lee et al.   Cell Host & Microbe

Redirecting Lentiviral Vectors Pseudotyped with Sindbis Virus-Derived Envelope Proteins to DC-SIGN by Modification of N-Linked Glycans of Envelope Proteins

(2010) K. Morizono et al.   JOURNAL OF VIROLOGY

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

(2010) Marina Cavazzana-Calvo et al.   NATURE

Stem-Cell Gene Therapy for the Wiskott–Aldrich Syndrome

(2010) Kaan Boztug et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Functional Henipavirus Envelope Glycoprotein Pseudotyped Lentivirus Assay System

(2010) Dimple Khetawat et al.   Virology Journal

Identification of Nectin-4 Oncoprotein as a Diagnostic and Therapeutic Target for Lung Cancer

(2009) A. Takano et al.   CANCER RESEARCH

Internalization and fusion mechanism of vesicular stomatitis virus and related rhabdoviruses

(2009) Xiangjie Sun et al.   Future Virology

The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy

(2009) Eugenio Montini et al.   JOURNAL OF CLINICAL INVESTIGATION

Insertional Transformation of Hematopoietic Cells by Self-inactivating Lentiviral and Gammaretroviral Vectors

(2009) Ute Modlich et al.   MOLECULAR THERAPY

Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy

(2009) N. Cartier et al.   SCIENCE

Characterization of Chikungunya pseudotyped viruses: Identification of refractory cell lines and demonstration of cellular tropism differences mediated by mutations in E1 glycoprotein

(2009) Beatriz Salvador et al.   VIROLOGY

Targeted Cell Entry of Lentiviral Vectors

(2008) Sabrina Funke et al.   MOLECULAR THERAPY