Coumarin hybrid derivatives as promising leads to treat tuberculosis: Recent developments and critical aspects of structural design to exhibit anti-tubercular activity

Potential role of adjuvant drugs on efficacy of first line oral antitubercular therapy: Drug repurposing

(2020) Ritu Mishra et al.   TUBERCULOSIS

New chalcone-sulfonamide hybrids exhibiting anticancer and antituberculosis activity

(2019) Lina Fernanda Castaño et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

4-Thiazolidinone coumarin derivatives as two-component NS2B/NS3 DENV flavivirus serine protease inhibitors: synthesis, molecular docking, biological evaluation and structure–activity relationship studies

(2018) Samina Khan Yusufzai et al.   Chemistry Central Journal

Synthesis and bio-evaluation of indole-chalcone based benzopyrans as promising antiligase and antiproliferative agents

(2018) Sampa Gupta et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of coumarin-theophylline hybrids as a new class of anti-tubercular and anti-microbial agents

(2018) Sumitra N. Mangasuli et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and evaluation of novel coumarin-oxime ethers as potential anti-tubercular agents: Their DNA cleavage ability and BSA interaction study

(2018) Dinesh S. Reddy et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and evaluation of oxime-functionalized nitrofuranylamides as novel antitubercular agents

(2018) Yi-Lei Fan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Recent developments of coumarin-containing derivatives and their anti-tubercular activity

(2017) Yuan-Qiang Hu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Azide-alkyne cycloaddition towards 1H-1,2,3-triazole-tethered gatifloxacin and isatin conjugates: Design, synthesis and in vitro anti-mycobacterial evaluation

(2017) Zhi Xu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Pyrrole: An emerging scaffold for construction of valuable therapeutic agents

(2016) Somnath S. Gholap   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Recent developments of C-4 substituted coumarin derivatives as anticancer agents

(2016) Jyoti Dandriyal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of α,β-Unsaturated Carbonyl-Based Compounds, Oxime and Oxime Ether Analogs as Potential Anticancer Agents for Overcoming Cancer Multidrug Resistance by Modulation of Efflux Pumps in Tumor Cells

(2016) Hua-Li Qin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Practical Pd(TFA)2-Catalyzed Aerobic [4+1] Annulation for the Synthesis of Pyrroles via “One-Pot” Cascade Reactions

(2016) Yang Yu et al.   Catalysts

Design, synthesis of benzocoumarin-pyrimidine hybrids as novel class of antitubercular agents, their DNA cleavage and X-ray studies

(2015) Dinesh S. Reddy et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Multi-target tacrine-coumarin hybrids: Cholinesterase and monoamine oxidase B inhibition properties against Alzheimer's disease

(2015) Sai-Sai Xie et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Recent progress in the drug development of coumarin derivatives as potent antituberculosis agents

(2015) Rangappa S. Keri et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A click chemistry approach for the synthesis of mono and bis aryloxy linked coumarinyl triazoles as anti-tubercular agents

(2015) Ashish Anand et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Tandem β-Elimination/Hetero-Michael Addition Rearrangement of an N-Alkylated Pyridinium Oxime to an O-Alkylated Pyridine Oxime Ether: An Experimental and Computational Study

(2015) Igor Picek et al.   JOURNAL OF ORGANIC CHEMISTRY

Microwave-assisted synthesis of new fluorinated coumarin–pyrimidine hybrids as potent anticancer agents, their DNA cleavage and X-ray crystal studies

(2015) Kallappa. M. Hosamani et al.   RSC Advances

Spirochromone-chalcone conjugates as antitubercular agents: synthesis, bio evaluation and molecular modeling studies

(2015) M. Mujahid et al.   RSC Advances

Novel hybrid-pyrrole derivatives: their synthesis, antitubercular evaluation and docking studies

(2015) Rikta Saha et al.   RSC Advances

3-(1-Phenyl-4-((2-(4-arylthiazol-2-yl)hydrazono)methyl)-1H-pyrazol-3-yl)-2H-chromen-2-ones: one-pot three component condensation, in vitro antimicrobial, antioxidant and molecular docking studies

(2015) Ramesh Gondru et al.   RSC Advances

A facile synthesis and evaluation of new biomolecule-based coumarin–thiazoline hybrids as potent anti-tubercular agents with cytotoxicity, DNA cleavage and X-ray studies

(2015) Dinesh S. Reddy et al.   RSC Advances

Quinoline: A promising antitubercular target

(2014) Rangappa S. Keri et al.   BIOMEDICINE & PHARMACOTHERAPY

Theophylline-7-acetic acid derivatives with amino acids as anti-tuberculosis agents

(2014) Yulian Voynikov et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of novel 4-nitropyrrole-based semicarbazide and thiosemicarbazide hybrids with antimicrobial and anti-tubercular activity

(2014) Rajesh A. Rane et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Modified Pyridine-Substituted Coumarins: A New Class of Antimicrobial and Antitubercular Agents

(2014) Rakesh R. Giri et al.   SYNTHETIC COMMUNICATIONS

Triazole containing novobiocin and biphenyl amides as Hsp90 C-terminal inhibitors

(2014) Jinbo Zhao et al.   MedChemComm

Syntheses of lipophilic chalcones and their conformationally restricted analogues as antitubercular agents

(2013) Imran Ahmad et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Review on Natural Coumarin Lead Compounds for Their Pharmacological Activity

(2013) K. N. Venugopala et al.   Biomed Research International

Click Chemistry Approach for Bis-Chromenyl Triazole Hybrids and Their Antitubercular Activity

(2012) Reshma J. Naik et al.   Chemical Biology & Drug Design

Evaluation of Structurally Diverse Benzoazepines Clubbed with Coumarins asMycobacterium tuberculosisAgents

(2012) Kuldip Upadhyay et al.   Chemical Biology & Drug Design

Recent Researches in Triazole Compounds as Medicinal Drugs

(2012) C. -H. Zhou et al.   CURRENT MEDICINAL CHEMISTRY

Quinolinyl Pyrimidines: Potent Inhibitors of NDH-2 as a Novel Class of Anti-TB Agents

(2012) Pravin S. Shirude et al.   ACS Medicinal Chemistry Letters

C-7 oxygenated coumarins from the fruits of Micromelum minutum

(2011) Ratsami Lekphrom et al.   ARCHIVES OF PHARMACAL RESEARCH

Synthesis and antimicrobial activity of amido linked pyrrolyl and pyrazolyl-oxazoles, thiazoles and imidazoles

(2011) V. Padmavathi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and anticancer activity of chalcone-pyrrolobenzodiazepine conjugates linked via 1,2,3-triazole ring side-armed with alkane spacers

(2011) Ahmed Kamal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel coumarin derivatives as potential antidyslipidemic agents

(2010) Koneni V. Sashidhara et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of novel benzocoumarin derivatives as lipid lowering agents

(2010) Koneni V. Sashidhara et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Conventional and microwave assisted synthesis of 2-oxo-4-substituted aryl-azetidine derivatives of benzotriazole: A new class of biological compounds

(2010) Adesh Dubey et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A Novel Dimeric Coumarin Analog and Antimycobacterial Constituents from Fatoua pilosa

(2010) Chun-Ching Chiang et al.   CHEMISTRY & BIODIVERSITY

Synthesis and in vitro antimycobacterial activity of balofloxacin ethylene isatin derivatives

(2010) Lian-Shun Feng et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of new pyrrolo[2,3-d]pyrimidine derivatives as antibacterial and antifungal agents

(2010) Khalid Mohammed Hassan Hilmy et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Analgesic, anti-pyretic and DNA cleavage studies of novel pyrimidine derivatives of coumarin moiety

(2010) Rangappa S. Keri et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Pharmacological significance of triazole scaffold

(2010) Rajeev Kharb et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Novel Synthesis of Hydrazide-Hydrazone Derivatives and Their Utilization in the Synthesis of Coumarin, Pyridine, Thiazole and Thiophene Derivatives with Antitumor Activity

(2010) Rafat M. Mohareb et al.   MOLECULES

Overview of the Chemistry of 2-Thiazolines

(2009) Annie-Claude Gaumont et al.   CHEMICAL REVIEWS

1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: Design, synthesis, and microbiological evaluation

(2009) Mariangela Biava et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and evaluation of in vitro anti-microbial and anti-tubercular activity of 2-styryl benzimidazoles

(2009) Ramya V. Shingalapur et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Challenges, successes and hopes in the development of novel TB therapeutics

(2009) Leonard V Sacks et al.   Future Medicinal Chemistry

Early Bactericidal Activity and Pharmacokinetics of the Diarylquinoline TMC207 in Treatment of Pulmonary Tuberculosis

(2008) R. Rustomjee et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Quantitative structure–activity relationship studies on nitrofuranyl anti-tubercular agents

(2008) Kirk E. Hevener et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and SAR studies of biaryloxy-substituted triazoles as antifungal agents

(2008) Ping Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Tetrahydronaphthyl azole oxime ethers: The conformationally rigid analogues of oxiconazole as antibacterials☆

(2008) Kalpana Bhandari et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Recent advances in the synthesis of purine derivatives and their precursors

(2008) Michel Legraverend   TETRAHEDRON

Synthesis, screening for antitubercular activity and 3D-QSAR studies of substituted N-phenyl-6-methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxamides

(2007) Vijay Virsodia et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of new 4-pyrrol-1-yl benzoic acid hydrazide analogs and some derived oxadiazole, triazole and pyrrole ring systems: A novel class of potential antibacterial and antitubercular agents

(2007) S.D. Joshi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY