Pharmacological significance of triazole scaffold

The Immunosuppressor ST1959, a 3,5-Diaryl-S-Triazole Derivative, Inhibits T Cell Activation by Reducing NFAT Nuclear Residency

(2017) R. Lindstedt et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Fluorinated 1,2,4-Triazolo[1,5-a]pyrimidine-6-carboxylic Acid Derivatives as Antimycobacterial Agents

(2009) Hamdy M. Abdel-Rahman et al.   ARCHIV DER PHARMAZIE

Design, synthesis and biological evaluation of novel triazole, urea and thiourea derivatives of quinoline against Mycobacterium tuberculosis

(2009) Ram Shankar Upadhayaya et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of novel 3-(1-(1-substituted piperidin-4-yl)-1H-1,2,3-triazol-4-yl)-1,2,4-oxadiazol-5(4H)-one as antifungal agents

(2009) Jaiprakash N. Sangshetti et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The use of oxadiazole and triazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 1: Establishing the pharmacophore

(2009) Brian A. Johns et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, structure elucidation and antitumour activity of N-substituted amides of 3-(3-ethylthio-1,2,4-triazol-5-yl)propenoic acid

(2009) Anna Pachuta-Stec et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of 3,6-disubstituted [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives as a novel class of potential anti-tumor agents

(2009) D.A. Ibrahim   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antiviral evaluation of N-amino-1,2,3-triazoles against Cantagalo virus replication in cell culture

(2009) Alessandro K. Jordão et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Regioselective reaction: Synthesis, characterization and pharmacological studies of some new Mannich bases derived from 1,2,4-triazoles

(2009) Arun M. Isloor et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New generation azole antifungals in clinical investigation

(2009) Corrado Girmenia   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Effectiveness of a Letter Notification Program for Women With Early-Stage Breast Cancer Eligible for Extended Adjuvant Letrozole

(2009) Heather L. McArthur et al.   JOURNAL OF CLINICAL ONCOLOGY

Design, Synthesis, and Evaluation of Novel Fluoroquinolone−Aminoglycoside Hybrid Antibiotics

(2009) Varvara Pokrovskaya et al.   JOURNAL OF MEDICINAL CHEMISTRY

Identification of a Metabolically Stable Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Antimalarial Activity in Mice

(2009) Ramesh Gujjar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Biological Activity of Some New 1,3,4-Thiadiazole and 1,2,4-Triazole Compounds Containing a Phenylalanine Moiety

(2009) Mihaela Moise et al.   MOLECULES

Synthesis, anticonvulsant and toxicity evaluation of 2-(1H-indol-3-yl)acetyl-N-(substituted phenyl)hydrazine carbothioamides and their related heterocyclic derivatives

(2008) Nadeem Siddiqui et al.   ACTA PHARMACEUTICA

Synthesis and evaluation of analgesic, anti-inflammatory and ulcerogenic activities of some triazolo- and 2-pyrazolyl-pyrido[2,3-d]-pyrimidines

(2008) Hend Hafez et al.   ACTA PHARMACEUTICA

Posaconazole: An Oral Triazole with an Extended Spectrum of Activity

(2008) Erik J Rachwalski et al.   ANNALS OF PHARMACOTHERAPY

Synthesis and cyclooxygenase inhibition of various (aryl-1,2,3-triazole-1-yl)-methanesulfonylphenyl derivatives

(2008) Frank Wuest et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Phenylcyclobutyl triazoles as selective inhibitors of 11β-hydroxysteroid dehydrogenase type I

(2008) Yuping Zhu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and SAR studies of biaryloxy-substituted triazoles as antifungal agents

(2008) Ping Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of 1,2,3-triazole-linked pyrrolobenzodiazepine conjugates employing ‘click’ chemistry: DNA-binding affinity and anticancer activity

(2008) Ahmed Kamal et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Clubbed [1,2,3] triazoles by fluorine benzimidazole: A novel approach to H37Rv inhibitors as a potential treatment for tuberculosis

(2008) Charansingh Gill et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inhibition of human mitochondrial carbonic anhydrases VA and VB with para-(4-phenyltriazole-1-yl)-benzenesulfonamide derivatives

(2008) Sally-Ann Poulsen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and Cytotoxicity Studies of Novel [1,2,4]Triazolo[1,5-a]pyrimidine-7-amines

(2008) Xin Zhai et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Combinatorial library methodology applied to cancer and protease targets

(2008) Paul J. Edwards   DRUG DISCOVERY TODAY

1,3,4-Oxadiazole/thiadiazole and 1,2,4-triazole derivatives of biphenyl-4-yloxy acetic acid: Synthesis and preliminary evaluation of biological properties

(2008) Harish Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

SAR study of clubbed [1,2,4]-triazolyl with fluorobenzimidazoles as antimicrobial and antituberculosis agents

(2008) Ganesh Rajaram Jadhav et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A Series of Potent and Selective, Triazolylphenyl-Based Histone Deacetylases Inhibitors with Activity against Pancreatic Cancer Cells andPlasmodium falciparum

(2008) Yufeng Chen et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Copper(I)-Catalyzed 1,2,3-Triazole Azide−Alkyne Click Compound Is a Potent Inhibitor of a Multidrug-Resistant HIV-1 Protease Variant

(2008) Michael J. Giffin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Parkinson's disease: clinical features and diagnosis

(2008) J Jankovic   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

In vitro efficacy of ribavirin against canine distemper virus

(2007) Gabriella Elia et al.   ANTIVIRAL RESEARCH

Synthesis, determination of the lipophilicity, anticancer and antimicrobial properties of some fused 1,2,4-triazole derivatives

(2007) Krzysztof Sztanke et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of novel substituted 1,3-diaryl propenone derivatives and their antimalarial activity in vitro

(2007) Nidhi Mishra et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Click chemistry reactions in medicinal chemistry: Applications of the 1,3-dipolar cycloaddition between azides and alkynes

(2007) Gian Cesare Tron et al.   MEDICINAL RESEARCH REVIEWS