A highly conserved glutamic acid in ALFY inhibits membrane binding to aid in aggregate clearance

Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake

(2020) Arjen J. Jakobi et al.   Nature Communications

Huntington’s Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy

(2019) Leora M. Fox et al.   NEURON

Phosphoinositide conversion in endocytosis and the endolysosomal system

(2017) Alexander Wallroth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Quality Control by Molecular Chaperones in Neurodegeneration

(2017) Aaron Ciechanover et al.   Frontiers in Neuroscience

Distinguishing aggregate formation and aggregate clearance using cell-based assays

(2016) Evelien Eenjes et al.   JOURNAL OF CELL SCIENCE

ProViz—a web-based visualization tool to investigate the functional and evolutionary features of protein sequences

(2016) Peter Jehl et al.   NUCLEIC ACIDS RESEARCH

Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures

(2014) A. H. Lystad et al.   EMBO REPORTS

PhosphoSitePlus, 2014: mutations, PTMs and recalibrations

(2014) Peter V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

Protein quality control and elimination of protein waste: The role of the ubiquitin–proteasome system

(2013) Ingo Amm et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The role of ALFY in selective autophagy

(2012) P Isakson et al.   CELL DEATH AND DIFFERENTIATION

NMR Analyses of the Interaction between the FYVE Domain of Early Endosome Antigen 1 (EEA1) and Phosphoinositide Embedded in a Lipid Bilayer

(2012) Mariko Yokogawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular Strategies of Protein Quality Control

(2011) B. Chen et al.   Cold Spring Harbor Perspectives in Biology

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins

(2010) Eisuke Itakura et al.   Autophagy

p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy

(2010) Terje Høyvarde Clausen et al.   Autophagy

The Selective Macroautophagic Degradation of Aggregated Proteins Requires the PI3P-Binding Protein Alfy

(2010) Maria Filimonenko et al.   MOLECULAR CELL

Protein aggregation diseases: pathogenicity and therapeutic perspectives

(2010) Adriano Aguzzi et al.   NATURE REVIEWS DRUG DISCOVERY

The elimination of accumulated and aggregated proteins: A role for aggrephagy in neurodegeneration

(2010) Ai Yamamoto et al.   NEUROBIOLOGY OF DISEASE

Membrane insertion of the FYVE domain is modulated by pH

(2009) Ju He et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

(2008) Elizabeth L. Axe et al.   JOURNAL OF CELL BIOLOGY

A Picky Eater: Exploring the Mechanisms of Selective Autophagy in Human Pathologies

(2008) Aniek van der Vaart et al.   TRAFFIC