Cytotoxicity comparison of 35 developmental neurotoxicants in human induced pluripotent stem cells (iPSC), iPSC-derived neural progenitor cells, and transformed cell lines

Human Induced Pluripotent Stem Cell-Derived 3D-Neurospheres Are Suitable for Neurotoxicity Screening

(2020) Julianna Kobolak et al.   Cells

The role of Pax6 in brain development and its impact on pathogenesis of autism spectrum disorder

(2018) Takako Kikkawa et al.   BRAIN RESEARCH

Development of the concept for stem cell-based Developmental Neurotoxicity (DNT) evaluation

(2018) Ellen Fritsche et al.   TOXICOLOGICAL SCIENCES

OUP accepted manuscript

(2018)   TOXICOLOGICAL SCIENCES

Testing for developmental neurotoxicity using a battery of in vitro assays for key cellular events in neurodevelopment

(2018) Joshua A. Harrill et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

(2018) Ellen Fritsche et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Strategies to improve the regulatory assessment of developmental neurotoxicity (DNT) using in vitro methods

(2018) Anna Bal-Price et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity

(2018) Anna Bal-Price   ALTEX-Alternatives to Animal Experimentation

OUP accepted manuscript

(2018)   TOXICOLOGICAL SCIENCES

Tributyltin Inhibits Neural Induction of Human Induced Pluripotent Stem Cells

(2018) Shigeru Yamada et al.   Scientific Reports

Chlorpyrifos inhibits neural induction via Mfn1-mediated mitochondrial dysfunction in human induced pluripotent stem cells

(2017) Shigeru Yamada et al.   Scientific Reports

Comparative neurotoxicity screening in human iPSC-derived neural stem cells, neurons and astrocytes

(2016) Ying Pei et al.   BRAIN RESEARCH

Microtubule and microtubule associated protein anomalies in psychiatric disease

(2016) Francesca Marchisella et al.   Cytoskeleton

Behavioral difficulties in 7-year old children in relation to developmental exposure to perfluorinated alkyl substances

(2016) Youssef Oulhote et al.   ENVIRONMENT INTERNATIONAL

Plasma phthalate and bisphenol a levels and oxidant-antioxidant status in autistic children

(2016) Meda Kondolot et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Developmental neurotoxicity test guidelines: problems and perspectives

(2016) Chiharu Tohyama   JOURNAL OF TOXICOLOGICAL SCIENCES

Neurite outgrowth in human induced pluripotent stem cell-derived neurons as a high-throughput screen for developmental neurotoxicity or neurotoxicity

(2016) Kristen R. Ryan et al.   NEUROTOXICOLOGY

Pyrethroid insecticide exposure and cognitive developmental disabilities in children: The PELAGIE mother–child cohort

(2015) Jean-François Viel et al.   ENVIRONMENT INTERNATIONAL

Developmental neurotoxic effects of two pesticides: Behavior and biomolecular studies on chlorpyrifos and carbaryl

(2015) Iwa Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Neurobehavioural effects of developmental toxicity

(2014) Philippe Grandjean et al.   LANCET NEUROLOGY

Developmental Consequences of Fetal Exposure to Drugs: What We Know and What We Still Must Learn

(2014) Emily J Ross et al.   NEUROPSYCHOPHARMACOLOGY

Otx2 and Oct4 Drive Early Enhancer Activation during Embryonic Stem Cell Transition from Naive Pluripotency

(2014) Shen-Hsi Yang et al.   Cell Reports

Narrowing of the responsible region for severe developmental delay and autistic behaviors in WAGR syndrome down to 1.6 Mb includingPAX6,WT1, andPRRG4

(2013) Toshiyuki Yamamoto et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

The homeobox gene Otx2 in development and disease

(2013) Francis Beby et al.   EXPERIMENTAL EYE RESEARCH

Pesticide Exposure and Neurodevelopmental Outcomes: Review of the Epidemiologic and Animal Studies

(2013) Carol J. Burns et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Developmental neurotoxicity guideline study: Issues with methodology, evaluation and regulation*

(2012) Ryozo Tsuji et al.   CONGENITAL ANOMALIES

A Research Strategy to Discover the Environmental Causes of Autism and Neurodevelopmental Disabilities

(2012) Philip J Landrigan et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures

(2011) Bin-Kuan Chou et al.   CELL RESEARCH

Hep G2 is a hepatoblastoma-derived cell line

(2009) Dolores López-Terrada et al.   HUMAN PATHOLOGY

Testing for Carcinogens: Shift From Animals to Automation Gathers Steam—Slowly

(2009) Charlie Schmidt   JNCI-Journal of the National Cancer Institute

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY