Generating adverse outcome pathway (AOP) of inorganic arsenic-induced adult male reproductive impairment via integration of phenotypic analysis in comparative toxicogenomics database (CTD) and AOP wiki

The role of arsenic in obesity and diabetes

(2019) Tahereh Farkhondeh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The cross talk of adrenal and Leydig cell steroids in Leydig cells

(2019) Yiyan Wang et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Toxicity testing in the 21st century: progress in the past decade and future perspectives

(2019) D. Krewski et al.   ARCHIVES OF TOXICOLOGY

Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice

(2019) Yongli Han et al.   CHEMOSPHERE

Accessing an Expanded Exposure Science Module at the Comparative Toxicogenomics Database

(2018) Cynthia J. Grondin et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Chemical-Induced Phenotypes at CTD Help Inform the Predisease State and Construct Adverse Outcome Pathways

(2018) Allan Peter Davis et al.   TOXICOLOGICAL SCIENCES

Current EU research activities on combined exposure to multiple chemicals

(2018) Stephanie K. Bopp et al.   ENVIRONMENT INTERNATIONAL

Application of the adverse outcome pathway (AOP) approach to inform mode of action (MOA): A case study with inorganic arsenic

(2018) Harvey J. Clewell et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

The Comparative Toxicogenomics Database: update 2019

(2018) Allan Peter Davis et al.   NUCLEIC ACIDS RESEARCH

Metal/metalloid levels in urine and seminal plasma in relation to computer-aided sperm analysis motion parameters

(2018) Zhen-Zhen Wan et al.   CHEMOSPHERE

Enhanced histone H3K9 tri-methylation suppresses steroidogenesis in rat testis chronically exposed to arsenic

(2018) Ambreen Alamdar et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Metabolism, toxicity and anticancer activities of arsenic compounds

(2017) Islam Khairul et al.   Oncotarget

Associations of urinary metal levels with serum hormones, spermatozoa apoptosis and sperm DNA damage in a Chinese population

(2016) Yi-Xin Wang et al.   ENVIRONMENT INTERNATIONAL

Arsenic trioxide induces ROS activity and DNA damage, leading to G0/G1 extension in skin fibroblasts through the ATM-ATR-associated Chk pathway

(2016) Jutapon Chayapong et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Low-level environmental arsenic exposure correlates with unexplained male infertility risk

(2016) Xiaofei Wang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

An integrative data mining approach to identifying adverse outcome pathway signatures

(2016) Noffisat O. Oki et al.   TOXICOLOGY

Generating Gene Ontology-Disease Inferences to Explore Mechanisms of Human Disease at the Comparative Toxicogenomics Database

(2016) Allan Peter Davis et al.   PLoS One

Systems Toxicology of Male Reproductive Development: Profiling 774 Chemicals for Molecular Targets and Adverse Outcomes

(2015) Maxwell C.K. Leung et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Prenatal arsenic exposure alters the programming of the glucocorticoid signaling system during embryonic development

(2015) Katharine E. Caldwell et al.   NEUROTOXICOLOGY AND TERATOLOGY

The potential of AOP networks for reproductive and developmental toxicity assay development

(2015) Dries Knapen et al.   REPRODUCTIVE TOXICOLOGY

Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment

(2015) Yeyejide Adeleye et al.   TOXICOLOGY

Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA)

(2014) Knut Erik Tollefsen et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Melatonin Improves Mitochondrial Function by Promoting MT1/SIRT1/PGC-1 Alpha-Dependent Mitochondrial Biogenesis in Cadmium-Induced Hepatotoxicity In Vitro

(2014) Pan Guo et al.   TOXICOLOGICAL SCIENCES

Adverse Outcome Pathway Development II: Best Practices

(2014) Daniel L. Villeneuve et al.   TOXICOLOGICAL SCIENCES

Systems Biology and Birth Defects Prevention: Blockade of the Glucocorticoid Receptor Prevents Arsenic-Induced Birth Defects

(2013) Bhavesh K. Ahir et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Ranking Transitive Chemical-Disease Inferences Using Local Network Topology in the Comparative Toxicogenomics Database

(2012) Benjamin L. King et al.   PLoS One

Effect of vitamin E on sperm number and testis histopathology of sodium arsenite-treated rats

(2012) Hamid Reza Momeni et al.   Reproductive Biology

Inhibition of Androgen Receptor Transcriptional Activity as a Novel Mechanism of Action of Arsenic

(2009) Adena E. Rosenblatt et al.   MOLECULAR ENDOCRINOLOGY

Local Network Topology in Human Protein Interaction Data Predicts Functional Association

(2009) Hua Li et al.   PLoS One

Arsenic Trioxide Impairs Spermatogenesis via Reducing Gene Expression Levels in Testosterone Synthesis Pathway

(2008) Tzeon-Jye Chiou et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Risk of Erectile Dysfunction Induced by Arsenic Exposure through Well Water Consumption in Taiwan

(2008) Fang-I Hsieh et al.   ENVIRONMENTAL HEALTH PERSPECTIVES