γ-Amino phosphonates via the photocatalytic α-C–H alkylation of primary amines

Photocatalytic α‐Tertiary Amine Synthesis via C–H Alkylation of Unmasked Primary Amines

(2020) Alexander James Cresswell et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphine Oxides from a Medicinal Chemist’s Perspective: Physicochemical and in vitro Parameters Relevant for Drug Discovery

(2020) Peter Finkbeiner et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dual Catalytic Platform for Enabling sp3 α C–H Arylation and Alkylation of Benzamides

(2020) Alexander W. Rand et al.   ACS Catalysis

Photoredox-Catalyzed Site-Selective α-C(sp3 )−H Alkylation of Primary Amine Derivatives

(2019) Melissa A. Ashley et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct α-alkylation of primary aliphatic amines enabled by CO2 and electrostatics

(2018) Juntao Ye et al.   Nature Chemistry

Selective sp3 C–H alkylation via polarity-match-based cross-coupling

(2017) Chip Le et al.   NATURE

Recent progress in asymmetric synthesis of aminophosphonic acids mediated by chiral sulfinyl auxiliary

(2017) Marian Mikołajczyk et al.   PURE AND APPLIED CHEMISTRY

Organophosphorus Compounds at 80: Some Old and New Issues

(2017) Lucio G Costa   TOXICOLOGICAL SCIENCES

Peramivir Phosphonate Derivatives as Influenza Neuraminidase Inhibitors

(2016) Peng-Cheng Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel Easily Recyclable Bifunctional Phosphonic Acid Carrying Tripeptides for the Stereoselective Michael Addition of Aldehydes with Nitroalkenes

(2015) Margery Cortes-Clerget et al.   ADVANCED SYNTHESIS & CATALYSIS

Covalent Surface Modification of Oxide Surfaces

(2014) Sidharam P. Pujari et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Beyond C, H, O, and N! Analysis of the Elemental Composition of U.S. FDA Approved Drug Architectures

(2014) Brandon R. Smith et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of α-brominated phosphonates and their application as phosphate bioisosteres

(2014) A. Michael Downey et al.   MedChemComm

Continuous-Flow Oxidative Cyanation of Primary and Secondary Amines Using Singlet Oxygen

(2013) Dmitry B. Ushakov et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modulators of the Sphingosine 1-phosphate receptor 1

(2013) Mariangela Urbano et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Sphingosine 1-phosphate receptor agonists: a patent review (2010 – 2012)

(2013) Edward Roberts et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

2-Pyridonate Titanium Complexes for Chemoselectivity. Accessing Intramolecular Hydroaminoalkylation over Hydroamination

(2013) Eugene Chong et al.   ORGANIC LETTERS

Aminophosphonic Acids - Phosphorus Analogues of Natural Amino Acids.Part 1: Syntheses of α-Aminophosphonic Acids

(2012) Zbigniew H. Kudzin et al.   CURRENT ORGANIC CHEMISTRY

A general approach to enantiomeric γ-aminophosphonic acids using chiral sulfinimine methodology

(2011) Piotr Łyżwa et al.   HETEROATOM CHEMISTRY

The revival of fosfomycin

(2011) Argyris S. Michalopoulos et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Remarkable Potential of the α-Aminophosphonate/Phosphinate Structural Motif in Medicinal Chemistry

(2011) Artur Mucha et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Practical Synthesis of Zanamivir Phosphonate Congeners with Potent Anti-influenza Activity

(2011) Jiun-Jie Shie et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and structure–activity relationships of tyrosine-based inhibitors of autotaxin (ATX)

(2010) James E. East et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Recent synthesis of aminophosphonic acids as potential biological importance

(2009) Emilia D. Naydenova et al.   AMINO ACIDS

Titanium-Catalyzed Hydroaminoalkylation of Alkenes by CH Bond Activation at sp3Centers in the α-Position to a Nitrogen Atom

(2009) Raphael Kubiak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aminophosphonic Acids and Derivatives. Synthesis and Biological Applications

(2009) F. Orsini et al.   CURRENT MEDICINAL CHEMISTRY

Selective C−H Activation α to Primary Amines. Bridging Metallaaziridines for Catalytic, Intramolecular α-Alkylation

(2009) Jason A. Bexrud et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organophosphorus Compounds: Intervention in Mechanisms of Signal Transduction Relevant to Proliferative, Immunological and Circulatory Disorders

(2008) Nick Wardle et al.   CURRENT MEDICINAL CHEMISTRY

An overview of stereoselective synthesis of α-aminophosphonic acids and derivatives

(2008) Mario Ordóñez et al.   TETRAHEDRON