Direct α-alkylation of primary aliphatic amines enabled by CO2 and electrostatics

Selective sp3 C–H alkylation via polarity-match-based cross-coupling

(2017) Chip Le et al.   NATURE

Harnessing non-covalent interactions to exert control over regioselectivity and site-selectivity in catalytic reactions

(2017) Holly J. Davis et al.   Chemical Science

Synthetic Utilization of α-Aminoalkyl Radicals and Related Species in Visible Light Photoredox Catalysis

(2016) Kazunari Nakajima et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Hydrazone-Based exo -Directing-Group Strategy for β C−H Oxidation of Aliphatic Amines

(2016) Zhongxing Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Transformations of Alkyl C–H Bonds

(2016) Jian He et al.   CHEMICAL REVIEWS

Contra-thermodynamic Hydrogen Atom Abstraction in the Selective C–H Functionalization of Trialkylamine N-CH3 Groups

(2016) Joshua P. Barham et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-Catalyzed γ-C(sp3)–H Arylation of Free Amines Using a Transient Directing Group

(2016) Yongwei Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Amide-directed photoredox-catalysed C–C bond formation at unactivated sp3 C–H bonds

(2016) John C. K. Chu et al.   NATURE

Catalytic alkylation of remote C–H bonds enabled by proton-coupled electron transfer

(2016) Gilbert J. Choi et al.   NATURE

Biologically active γ-lactams: synthesis and natural sources

(2016) J. Caruano et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A general catalytic β-C–H carbonylation of aliphatic amines to β-lactams

(2016) Darren Willcox et al.   SCIENCE

Native functionality in triple catalytic cross-coupling: sp3 C-H bonds as latent nucleophiles

(2016) M. H. Shaw et al.   SCIENCE

Amine Functionalization via Oxidative Photoredox Catalysis: Methodology Development and Complex Molecule Synthesis

(2015) Joel W. Beatty et al.   ACCOUNTS OF CHEMICAL RESEARCH

Platinum-Catalyzed, Terminal-Selective C(sp3)–H Oxidation of Aliphatic Amines

(2015) Melissa Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Remote Oxidation of Aliphatic C–H Bonds in Nitrogen-Containing Molecules

(2015) Jennifer M. Howell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A steric tethering approach enables palladium-catalysed C–H activation of primary amino alcohols

(2015) Jonas Calleja et al.   Nature Chemistry

O-H hydrogen bonding promotes H-atom transfer from   C-H bonds for C-alkylation of alcohols

(2015) J. L. Jeffrey et al.   SCIENCE

Solar Synthesis: Prospects in Visible Light Photocatalysis

(2014) D. M. Schultz et al.   SCIENCE

Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis

(2013) Christopher K. Prier et al.   CHEMICAL REVIEWS

Carbon dioxide as a reversible amine-protecting agent in selective Michael additions and acylations

(2013) Annelies Peeters et al.   GREEN CHEMISTRY

A General Strategy for Organocatalytic Activation of C–H Bonds via Photoredox Catalysis: Direct Arylation of Benzylic Ethers

(2013) Katrine Qvortrup et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Titanium-Catalyzed Hydroaminoalkylation of Alkenes by CH Bond Activation at sp3Centers in the α-Position to a Nitrogen Atom

(2009) Raphael Kubiak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Selective C−H Activation α to Primary Amines. Bridging Metallaaziridines for Catalytic, Intramolecular α-Alkylation

(2009) Jason A. Bexrud et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY