Dose- and time-dependent increase in circulating anti-inflammatory and pro-resolving lipid mediators following eicosapentaenoic acid supplementation in patients with major depressive disorder and chronic inflammation

Plasma oxylipins respond in a linear dose-response manner with increased intake of EPA and DHA: results from a randomized controlled trial in healthy humans

(2019) Annika I Ostermann et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Resolvin E3 attenuates allergic airway inflammation via the interleukin-23–interleukin-17A pathway

(2019) Makiko Sato et al.   FASEB JOURNAL

Efficacy of omega-3 PUFAs in depression: A meta-analysis

(2019) Yuhua Liao et al.   Translational Psychiatry

Different metabolism of EPA, DPA and DHA in humans: A double-blind cross-over study

(2019) Xiao-fei Guo et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Enriched Marine Oil Supplements Increase Peripheral Blood Specialized Pro-Resolving Mediators Concentrations and Reprogram Host Immune Responses

(2019) Patricia R. Souza et al.   CIRCULATION RESEARCH

Frontline Science: Specialized proresolving lipid mediators inhibit the priming and activation of the macrophage NLRP3 inflammasome

(2018) Aritz Lopategi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Resolvin E3 attenuates lipopolysaccharide-induced depression-like behavior in mice

(2018) Satoshi Deyama et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Influence of adjuvant omega-3-polyunsaturated fatty acids on depression, sleep, and emotion regulation among outpatients with major depressive disorders - Results from a double-blind, randomized and placebo-controlled clinical trial

(2018) Leila Jahangard et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia

(2018) Deepak L. Bhatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of specialized pro-resolving mediator clusters from healthy adults after intravenous low-dose endotoxin and omega-3 supplementation: a methodological validation

(2018) Paul C. Norris et al.   Scientific Reports

Protectin D1n-3 DPAand resolvin D5n-3 DPAare effectors of intestinal protection

(2017) Thomas Gobbetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of omega-3 oxylipins in human plasma and response to treatment with omega-3 acid ethyl esters

(2017) Gregory C. Shearer et al.   JOURNAL OF LIPID RESEARCH

Inflammation as a predictive biomarker for response to omega-3 fatty acids in major depressive disorder: a proof-of-concept study

(2015) M H Rapaport et al.   MOLECULAR PSYCHIATRY

Short-term supplementation of acute long-chain omega-3 polyunsaturated fatty acids may alter depression status and decrease symptomology among young adults with depression: A preliminary randomized and placebo controlled trial

(2015) Annie T. Ginty et al.   PSYCHIATRY RESEARCH

Changes in PTGS1 and ALOX12 Gene Expression in Peripheral Blood Mononuclear Cells Are Associated with Changes in Arachidonic Acid, Oxylipins, and Oxylipin/Fatty Acid Ratios in Response to Omega-3 Fatty Acid Supplementation

(2015) Claire C. Berthelot et al.   PLoS One

Eicosanomic profiling reveals dominance of the epoxygenase pathway in human amniotic fluid at term in spontaneous labor

(2014) Krishna Rao Maddipati et al.   FASEB JOURNAL

Proresolving Lipid Mediators and Mechanisms in the Resolution of Acute Inflammation

(2014) Christopher D. Buckley et al.   IMMUNITY

Dietary omega-3 fatty acids modulate the eicosanoid profile in man primarily via the CYP-epoxygenase pathway

(2014) Robert Fischer et al.   JOURNAL OF LIPID RESEARCH

Increase of EPA-derived hydroxy, epoxy and dihydroxy fatty acid levels in human plasma after a single dose of long-chain omega-3 PUFA

(2014) Jan Philipp Schuchardt et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Nonesterified Fatty Acid Determination for Functional Lipidomics: Comprehensive Ultrahigh Performance Liquid Chromatography–Tandem Mass Spectrometry Quantitation, Qualification, and Parameter Prediction

(2012) Christian Hellmuth et al.   ANALYTICAL CHEMISTRY

Identification and Structure Determination of Novel Anti-inflammatory Mediator Resolvin E3, 17,18-Dihydroxyeicosapentaenoic Acid

(2012) Yosuke Isobe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resolvin E2 Formation and Impact in Inflammation Resolution

(2012) S. F. Oh et al.   JOURNAL OF IMMUNOLOGY

ALOX5 gene variants affect eicosanoid production and response to fish oil supplementation

(2011) Charles B. Stephensen et al.   JOURNAL OF LIPID RESEARCH

Association Between Depression and Inflammation-Differences by Race and Sex

(2011) Alanna AMYRE Morris et al.   PSYCHOSOMATIC MEDICINE

Inflammation in Atherosclerosis:

(2010) Peter Libby et al.   CIRCULATION JOURNAL

Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators

(2008) Aksam J. Merched et al.   FASEB JOURNAL