Article
Cardiac & Cardiovascular Systems
Frank Qian, Nathan Tintle, Paul N. Jensen, Rozenn N. Lemaitre, Fumiaki Imamura, Tobias Rudholm Feldreich, Sarah Oppeneer Nomura, Weihua Guan, Federica Laguzzi, Eunjung Kim, Jyrki K. Virtanen, Marinka Steur, Christian S. Bork, Yoichiro Hirakawa, Michelle L. O'Donoghue, Aleix Sala-Vila, Andres V. Ardisson Korat, Qi Sun, Eric B. Rimm, Bruce M. Psaty, Susan R. Heckbert, Nita G. Forouhi, Nicholas J. Wareham, Matti Marklund, Ulf Riserus, Lars Lind, Johan Arnlov, Parveen Garg, Michael Y. Tsai, James Pankow, Jeffrey R. Misialek, Bruna Gigante, Karin Leander, Julie A. Pester, Christine M. Albert, Maryam Kavousi, Arfan Ikram, Trudy Voortman, Erik B. Schmidt, Toshiharu Ninomiya, David A. Morrow, Antoni Bayes-Genis, James H. O'Keefe, Kwok Leung Ong, Jason H. Y. Wu, Dariush Mozaffarian, William S. Harris, David S. Siscovick
Summary: This study aimed to determine the associations of blood or adipose tissue levels of EPA, DPA, and DHA with incident AF. Using participant-level data from 17 prospective cohort studies, it was found that levels of omega-3 fatty acids, including EPA, DPA, DHA, and EPA+DHA, were not associated with increased risk of incident AF.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Medicine, Research & Experimental
Linda Ljungblad, Filip Bergqvist, Conny Tummler, Samanthi Madawala, Thale Kristin Olsen, Teodora Andonova, Per-Johan Jakobsson, John Inge Johnsen, Jana Pickova, Birgitta Strandvik, Per Kogner, Helena Gleissman, Malin Wickstrom
Summary: The study demonstrated that omega 3-LCPUFA had negative effects on medulloblastoma cells, reducing their viability, clonogenic ability, and inducing apoptosis. DHA showed a tumor growth-inhibiting effect in vivo and decreased inflammatory factors in tumor tissues.
Article
Food Science & Technology
Fernanda de Melo Ramos, Vivaldo Silveira Junior, Ana Silvia Prata
Summary: The study demonstrated that vacuum spray drying technology can provide better protection against lipid oxidation for active materials, while spray drying technology had poorer performance and lower encapsulation efficiency.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Biochemistry & Molecular Biology
Shuai-Shuai Fu, Min Wen, Ying-Cai Zhao, Hao-Hao Shi, Yu-Ming Wang, Chang-Hu Xue, Zi-Hao Wei, Tian-Tian Zhang
Summary: A study found that dietary supplementation with EPA-pPE can significantly change the fatty acid composition in the brain and liver, especially in increasing the content of DHA. EPA-pPE has a more significant effect on increasing DHA compared to EPA-PC, making it a good nutritional supplement to increase DHA levels in n-3 PUFA-deficient offspring's brains.
Article
Fisheries
David Huyben, Teresa Grobler, Chessor Matthew, Marta Bou, Bente Ruyter, Brett Glencross
Summary: The requirement for omega-3 long-chain polyunsaturated fatty acids for Atlantic salmon is relative to the dietary lipid level, with high n-3 diets contributing to increased body weight and weight gain.
Article
Agriculture, Dairy & Animal Science
Paulo H. de Mello, Bruno C. Araujo, Victor H. Marques, Giovana S. Branco, Renato M. Honji, Renata G. Moreira, Artur N. Rombenso, Maria C. Portella
Summary: This study investigated the effects of different lipid classes on the physiological and morphological responses of dusky groupers. The results showed that including different lipid classes in the diet can improve fish fillet quality. Additionally, the study found that DHA and EPA have an impact on the morphophysiology of dusky grouper juveniles, providing valuable insights for establishing this fish species as a produced species worldwide.
Article
Pharmacology & Pharmacy
Chao Xuan, Qing-Wu Tian, Hui Li, Jun-Jie Guo, Guo-Wei He, Li-Min Lun
Summary: This study investigated the profile of fatty acids in the serum of EOCAD patients and identified a significant association between decreased levels of DHA, DPA, and EPA with EOCAD. Results indicated that elevated serum DHA level was an independent protective factor for EOCAD and MI. These findings contribute to understanding the cardiovascular effects of fatty acids, particularly the protective effects of omega-3 polyunsaturated fatty acids.
THERAPEUTIC ADVANCES IN CHRONIC DISEASE
(2021)
Article
Environmental Sciences
Ursula Strandberg, Minna Hiltunen, Jari Syvaeranta, Eti E. Levi, Thomas A. Davidson, Erik Jeppesen, Michael T. Brett
Summary: Climate change and eutrophication are key stressors for shallow freshwater ecosystems and have significant impacts on phytoplankton community structure. This study found that nutrient treatment had a significant effect on phytoplankton EPA and DHA concentrations, while warming had a marginal effect. The changes in EPA and DHA concentrations were mostly related to the phytoplankton community structure and biomass.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Nutrition & Dietetics
Felix Castillo Salinas, Alicia Montaner Ramon, Felix-Joel Castillo Ferrer, Adria Domingo-Carnice, Begona Cordobilla, Joan Carles Domingo
Summary: This study examines the differences in fatty acid profile between preterm and term neonates at birth and after 1 month. The findings indicate that preterm neonates have a deficiency in fatty acids at birth, which persists for the first month of life. This highlights the importance of adding DHA to milk banking and supplementing breastfeeding mothers with DHA.
Article
Biochemistry & Molecular Biology
L. Ljungblad, H. Gleissman, G. Hedberg, M. Wickstrom, N. Eissler, J. Pickova, J. I. Johnsen, K. Tedroff, B. Strandvik, P. Kogner
Summary: The study suggests that Ω-3 fatty acids can be used as a complementary treatment in cancer therapy, but the optimal dosage for children in remission needs further investigation. The dose-finding study showed that individualized supplementation based on body surface area can decrease variation in fatty acid levels among patients.
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
(2021)
Article
Fisheries
Marta Carvalho, Daniel Montero, Paolo Domenici, Juan Manuel Afonso, Marisol Izquierdo
Summary: N-3 long-chain polyunsaturated fatty acids (LC-PUFA), especially docosahexaenoic acid (22:6n-3, DHA), play a vital role in brain function of all vertebrates. Novel lipid sources, including those obtained from microorganisms, have become available for the industry. This study aimed to investigate the effects of different lipid sources on behavior and neural function in gilthead sea bream. It was found that the brain of sea bream fed poultry oil showed the highest DHA content and increased expression of genes related to LC-PUFA synthesis. The locomotor performance was not affected by the experimental diets, but there was a tendency for longer escape latency in fish fed poultry oil and microalgae oil combined with poultry oil diets.
Article
Agricultural Engineering
Nikhil L. Kadalag, Pratik R. Pawar, Gunjan Prakash
Summary: In this study, co-cultivation of Phaeodactylum tricornutum with Aurantiochytrium limacinum was used as a unique strategy to achieve the desired fatty acid composition. The initial cell density ratio was modulated to overcome the dominance of A. limacinum and regulate the proliferation of both species, resulting in the production of polyunsaturated fatty acids (PUFA) such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), as well as monounsaturated fatty acids (MUFA) and pigments.
BIORESOURCE TECHNOLOGY
(2022)
Article
Agriculture, Multidisciplinary
Xiao-Yu Cui, Shan Jiang, Cheng-Cheng Wang, Jin-Yue Yang, Ying-Cai Zhao, Chang-Hu Xue, Yu-Ming Wang, Tian-Tian Zhang
Summary: The study demonstrated that EPA-PC, EPA-LPC, and DHA-LPC have different effects on DHA or EPA recovery and supplementation efficiency in different tissues, providing important references for understanding the time course of DHA or EPA recovery in phospholipid molecular species in different tissues.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Nutrition & Dietetics
Yun-Jung Bae, Xiang-Shun Cui, Seung-Ho Shin
Summary: This study investigated the relationship between omega-3 fatty acid intake and sarcopenia in elderly Koreans. The results showed that elderly females with inadequate intake of EPA and DHA had lower grip strength and lower protein intake compared to those with adequate intake. Sufficient intake of EPA and DHA was found to be crucial in mitigating a reduction in grip strength and improving nutrient intake quality among elderly females.
Review
Nutrition & Dietetics
Clemens von Schacky
Summary: The structure and function of the brain rely on a sufficient supply of EPA and DHA through the bloodstream. Lower Omega-3 Index levels are associated with increased risks, highlighting the importance of adequate intake of these essential fatty acids for optimal brain health.