Hyperkalaemia, not apoptosis, accurately predicts insect chilling injury

Maintenance of hindgut reabsorption during cold exposure is a key adaptation for Drosophila cold tolerance

(2020) Mads Kuhlmann Andersen et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Neural shutdown under stress: an evolutionary perspective on spreading depolarization

(2020) R. Meldrum Robertson et al.   JOURNAL OF NEUROPHYSIOLOGY

Neural dysfunction correlates with heat coma and CTmax in Drosophila but does not set the boundaries for heat stress survival

(2020) Lisa B. Jørgensen et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Chilling induces unidirectional solute leak through the locust gut epithelia

(2020) Kaylen Brzezinski et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Dissecting cause from consequence: a systematic approach to thermal limits

(2019) Heath A. MacMillan   JOURNAL OF EXPERIMENTAL BIOLOGY

Cold acclimation modulates voltage gated Ca2+ channel currents and fiber excitability in skeletal muscles of Locusta migratoria

(2019) Jeppe Seamus Bayley et al.   JOURNAL OF INSECT PHYSIOLOGY

Which Spreading Depolarizations Are Deleterious To Brain Tissue?

(2019) C. William Shuttleworth et al.   Neurocritical Care

Functional plasticity of the gut and the Malpighian tubules underlies cold acclimation and mitigates cold-induced hyperkalemia in Drosophila melanogaster

(2018) Gil Y. Yerushalmi et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Central nervous system shutdown underlies acute cold tolerance in tropical and temperateDrosophilaspecies

(2018) Mads Kuhlmann Andersen et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Cold exposure causes cell death by depolarization-mediated Ca2+ overload in a chill-susceptible insect

(2018) Jeppe Seamus Bayley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cold tolerance ofDrosophilaspecies is tightly linked to the epithelial K+transport capacity of the Malpighian tubules and rectal pads

(2017) Mads Kuhlmann Andersen et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Chill coma in the locust, Locusta migratoria, is initiated by spreading depolarization in the central nervous system

(2017) R. Meldrum Robertson et al.   Scientific Reports

Thermal acclimation mitigates cold-induced paracellular leak from the Drosophila gut

(2017) Heath A. MacMillan et al.   Scientific Reports

Roles of Caspases in Necrotic Cell Death

(2016) Junying Yuan et al.   CELL

Does oxygen limit thermal tolerance in arthropods? A critical review of current evidence

(2016) Wilco C.E.P. Verberk et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY

Caspases Connect Cell-Death Signaling to Organismal Homeostasis

(2016) Lorenzo Galluzzi et al.   IMMUNITY

Hemolymph metabolites and osmolality are tightly linked to cold tolerance ofDrosophilaspecies: a comparative study

(2016) Trine Olsson et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Cold acclimation improves chill tolerance in the migratory locust through preservation of ion balance and membrane potential

(2016) Mads Kuhlmann Andersen et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Sodium distribution predicts the chill tolerance of Drosophila melanogaster raised in different thermal conditions

(2015) Heath A. MacMillan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Muscle membrane potential and insect chill coma

(2015) J. L. Andersen et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

The multifaceted activity of insect caspases

(2015) A. Accorsi et al.   JOURNAL OF INSECT PHYSIOLOGY

Constraints, independence, and evolution of thermal plasticity: Probing genetic architecture of long- and short-term thermal acclimation

(2015) Alison R. Gerken et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concurrent effects of cold and hyperkalaemia cause insect chilling injury

(2015) Heath A. MacMillan et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The capacity to maintain ion and water homeostasis underlies interspecific variation in Drosophila cold tolerance

(2015) Heath A. MacMillan et al.   Scientific Reports

Old, new and emerging functions of caspases

(2014) S Shalini et al.   CELL DEATH AND DIFFERENTIATION

Cold-induced depolarization of insect muscle: differing roles of extracellular K+ during acute and chronic chilling

(2014) H. A. MacMillan et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Caspase levels and execution efficiencies determine the apoptotic potential of the cell

(2012) Anat Florentin et al.   JOURNAL OF CELL BIOLOGY

Calcium and cell death mechanisms: A perspective from the cell death community

(2011) Boris Zhivotovsky et al.   CELL CALCIUM

The role of the gut in insect chilling injury: cold-induced disruption of osmoregulation in the fall field cricket, Gryllus pennsylvanicus

(2011) H. A. MacMillan et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

The Relationship between Chill-Coma Onset and Recovery at the Extremes of the Thermal Window of Drosophila melanogaster

(2011) Victoria E. Ransberry et al.   PHYSIOLOGICAL AND BIOCHEMICAL ZOOLOGY

Rapid cold-hardening blocks cold-induced apoptosis by inhibiting the activation of pro-caspases in the flesh fly Sarcophaga crassipalpis

(2010) Shu-Xia Yi et al.   APOPTOSIS

Mechanisms underlying insect chill-coma

(2010) Heath A. MacMillan et al.   JOURNAL OF INSECT PHYSIOLOGY

The insect caspases

(2009) Dawn M. Cooper et al.   APOPTOSIS

Autophagy, Not Apoptosis, Is Essential for Midgut Cell Death in Drosophila

(2009) Donna Denton et al.   CURRENT BIOLOGY