Transfer RNA fragments replace microRNA regulators of the cholinergic poststroke immune blockade

Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

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A year-long immune profile of the systemic response in acute stroke survivors

(2019) Amy S Tsai et al.   BRAIN

MicroRNA and their target mRNAs change expression in whole blood of patients after intracerebral hemorrhage

(2019) Xiyuan Cheng et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Differential expression of human tRNA genes drives the abundance of tRNA-derived fragments

(2019) Adrian Gabriel Torres et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elevation of plasma tRNA fragments precedes seizures in human epilepsy

(2019) Marion C. Hogg et al.   JOURNAL OF CLINICAL INVESTIGATION

Integrative Transcriptomics Reveals Sexually Dimorphic Control of the Cholinergic/Neurokine Interface in Schizophrenia and Bipolar Disorder

(2019) Sebastian Lobentanzer et al.   Cell Reports

Microglia monitor and protect neuronal function through specialized somatic purinergic junctions

(2019) Csaba Cserép et al.   SCIENCE

ZBP1: Innate Sensor Regulating Cell Death and Inflammation

(2018) Teneema Kuriakose et al.   TRENDS IN IMMUNOLOGY

ATF3 Regulates the Expression of AChE During Stress

(2018) Ronit Heinrich et al.   Frontiers in Molecular Neuroscience

Experimental Stroke Differentially Affects Discrete Subpopulations of Splenic Macrophages

(2018) Laura McCulloch et al.   Frontiers in Immunology

Large Differences in Small RNA Composition Between Human Biofluids

(2018) Paula M. Godoy et al.   Cell Reports

Selective Export into Extracellular Vesicles and Function of tRNA Fragments during T Cell Activation

(2018) Ni-Ting Chiou et al.   Cell Reports

ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases

(2018) Doaa Glal et al.   Frontiers in Immunology

A transfer-RNA-derived small RNA regulates ribosome biogenesis

(2017) Hak Kyun Kim et al.   NATURE

MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1

(2017) Takashi Shichita et al.   NATURE MEDICINE

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

A comprehensive, cell specific microRNA catalogue of human peripheral blood

(2017) Simonas Juzenas et al.   NUCLEIC ACIDS RESEARCH

Expression and Function of the Cholinergic System in Immune Cells

(2017) Takeshi Fujii et al.   Frontiers in Immunology

MINTmap: fast and exhaustive profiling of nuclear and mitochondrial tRNA fragments from short RNA-seq data

(2017) Phillipe Loher et al.   Scientific Reports

Stroke-induced immunodepression and dysphagia independently predict stroke-associated pneumonia – The PREDICT study

(2016) Sarah Hoffmann et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Monocyte-Derived Macrophages Contribute to Spontaneous Long-Term Functional Recovery after Stroke in Mice

(2016) S. Wattananit et al.   JOURNAL OF NEUROSCIENCE

Weakened Cholinergic Blockade of Inflammation Associates with Diabetes-Related Depression

(2016) Shani Shenhar-Tsarfaty et al.   MOLECULAR MEDICINE

Tissue-specific regulatory circuits reveal variable modular perturbations across complex diseases

(2016) Daniel Marbach et al.   NATURE METHODS

The Role of Monocytes in Ischemic Stroke Pathobiology: New Avenues to Explore

(2016) Ayman ElAli et al.   Frontiers in Aging Neuroscience

tRNA-Derived Small Non-Coding RNAs in Response to Ischemia Inhibit Angiogenesis

(2016) Qing Li et al.   Scientific Reports

Endogenous tRNA-Derived Fragments Suppress Breast Cancer Progression via YBX1 Displacement

(2015) Hani Goodarzi et al.   CELL

ATF3 Is a Key Regulator of Macrophage IFN Responses

(2015) Larisa I. Labzin et al.   JOURNAL OF IMMUNOLOGY

fitdistrplus: AnRPackage for Fitting Distributions

(2015) Marie Laure Delignette-Muller et al.   Journal of Statistical Software

Cholinergic Pathway Suppresses Pulmonary Innate Immunity Facilitating Pneumonia After Stroke

(2015) Odilo Engel et al.   STROKE

Checks and balances on cholinergic signaling in brain and body function

(2015) Hermona Soreq   TRENDS IN NEUROSCIENCES

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

Meta-analysis of tRNA derived RNA fragments reveals that they are evolutionarily conserved and associate with AGO proteins to recognize specific RNA targets

(2014) Pankaj Kumar et al.   BMC BIOLOGY

The human miRNA repertoire of different blood compounds

(2014) Petra Leidinger et al.   BMC GENOMICS

Identification of Circulating MicroRNAs as Potential Biomarkers for Detecting Acute Ischemic Stroke

(2014) Pengfei Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Translational control of immune responses: from transcripts to translatomes

(2014) Ciriaco A Piccirillo et al.   NATURE IMMUNOLOGY

microRNA Expression in Peripheral Blood Cells following Acute Ischemic Stroke and Their Predicted Gene Targets

(2014) Glen C. Jickling et al.   PLoS One

Blood microRNAs in Low or No Risk Ischemic Stroke Patients

(2013) Jun Tan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma

(2013) Roy L. Maute et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Risk factors, inpatient care, and outcomes of pneumonia after ischemic stroke

(2011) O. Finlayson et al.   NEUROLOGY

A miRNA-tRNA mix-up: tRNA origin of proposed miRNA

(2011) Nick C.T. Schopman et al.   RNA Biology

Acetylcholine-Synthesizing T Cells Relay Neural Signals in a Vagus Nerve Circuit

(2011) M. Rosas-Ballina et al.   SCIENCE

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(2010) Einor Assayag et al.   MOLECULAR MEDICINE

miRExpress: Analyzing high-throughput sequencing data for profiling microRNA expression

(2009) Wei-Chi Wang et al.   BMC BIOINFORMATICS

Stressing Out over tRNA Cleavage

(2009) Debrah M. Thompson et al.   CELL

MicroRNA-132 Potentiates Cholinergic Anti-Inflammatory Signaling by Targeting Acetylcholinesterase

(2009) Iftach Shaked et al.   IMMUNITY

Angiogenin cleaves tRNA and promotes stress-induced translational repression

(2009) Satoshi Yamasaki et al.   JOURNAL OF CELL BIOLOGY

Monocyte Subtypes Predict Clinical Course and Prognosis in Human Stroke

(2009) Xabier Urra et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Sex differences in stroke: epidemiology, clinical presentation, medical care, and outcomes

(2008) Mathew J Reeves et al.   LANCET NEUROLOGY