Mutation bias within oncogene families is related to proliferation-specific codon usage

Translational efficiency across healthy and tumor tissues is proliferation‐related

(2020) Xavier Hernandez‐Alias et al.   Molecular Systems Biology

Novel Gastric Cancer Stem Cell-Related Marker LINGO2 Is Associated with Cancer Cell Phenotype and Patient Outcome

(2019) Jung Jo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Widespread and Functional RNA Circularization in Localized Prostate Cancer

(2019) Sujun Chen et al.   CELL

Translation affects mRNA stability in a codon-dependent manner in human cells

(2019) Qiushuang Wu et al.   eLife

A pan-cancer analysis of synonymous mutations

(2019) Yogita Sharma et al.   Nature Communications

Accurate mapping of tRNA reads

(2018) Anne Hoffmann et al.   BIOINFORMATICS

Posttranslational Modifications of RAS Proteins

(2018) Ian Ahearn et al.   Cold Spring Harbor Perspectives in Medicine

Repertoires of tRNAs: The Couplers of Genomics and Proteomics

(2018) Roni Rak et al.   Annual Review of Cell and Developmental Biology

Cells alter their tRNA abundance to selectively regulate protein synthesis during stress conditions

(2018) Marc Torrent et al.   Science Signaling

Codon usage regulates human KRAS expression at both transcriptional and translational levels

(2018) Jingjing Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Codon optimality, bias and usage in translation and mRNA decay

(2017) Gavin Hanson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Characterizing Expression and Processing of Precursor and Mature Human tRNAs by Hydro-tRNAseq and PAR-CLIP

(2017) Tasos Gogakos et al.   Cell Reports

H-Ras and K-Ras Oncoproteins Induce Different Tumor Spectra When Driven by the Same Regulatory Sequences

(2016) Matthias Drosten et al.   CANCER RESEARCH

The DEAD-Box Protein Dhh1p Couples mRNA Decay and Translation by Monitoring Codon Optimality

(2016) Aditya Radhakrishnan et al.   CELL

Modulated Expression of Specific tRNAs Drives Gene Expression and Cancer Progression

(2016) Hani Goodarzi et al.   CELL

RAS isoforms and mutations in cancer at a glance

(2016) G. Aaron Hobbs et al.   JOURNAL OF CELL SCIENCE

Codon influence on protein expression in E. coli correlates with mRNA levels

(2016) Grégory Boël et al.   NATURE

Single Synonymous Mutations in KRAS Cause Transformed Phenotypes in NIH3T3 Cells

(2016) Andrew M. Waters et al.   PLoS One

Codon Optimality Is a Major Determinant of mRNA Stability

(2015) Vladimir Presnyak et al.   CELL

K-Ras Promotes Tumorigenicity through Suppression of Non-canonical Wnt Signaling

(2015) Man-Tzu Wang et al.   CELL

OncodriveROLE classifies cancer driver genes in loss of function and activating mode of action

(2014) Michael P. Schroeder et al.   BIOINFORMATICS

A Dual Program for Translation Regulation in Cellular Proliferation and Differentiation

(2014) Hila Gingold et al.   CELL

Synonymous Mutations Frequently Act as Driver Mutations in Human Cancers

(2014) Fran Supek et al.   CELL

Rare codons capacitate Kras-driven de novo tumorigenesis

(2014) Nicole L.K. Pershing et al.   JOURNAL OF CLINICAL INVESTIGATION

Discovery and saturation analysis of cancer genes across 21 tumour types

(2014) Michael S. Lawrence et al.   NATURE

ArrayExpress update—simplifying data submissions

(2014) Nikolay Kolesnikov et al.   NUCLEIC ACIDS RESEARCH

Ras GTPases: Codon Bias Holds KRas Down but Not Out

(2013) Brian O. Bodemann et al.   CURRENT BIOLOGY

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model

(2013) Emilie A Bard-Chapeau et al.   NATURE GENETICS

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

IntOGen-mutations identifies cancer drivers across tumor types

(2013) Abel Gonzalez-Perez et al.   NATURE METHODS

A Comprehensive Survey of Ras Mutations in Cancer

(2012) I. A. Prior et al.   CANCER RESEARCH

Rare Codons Regulate KRas Oncogenesis

(2012) Benjamin L. Lampson et al.   CURRENT BIOLOGY

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

(2012) Christopher E Barbieri et al.   NATURE GENETICS

Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus

(2010) Q. Li et al.   BLOOD

tRNA over-expression in breast cancer and functional consequences

(2009) Mariana Pavon-Eternod et al.   NUCLEIC ACIDS RESEARCH

Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon

(2008) Kevin M Haigis et al.   NATURE GENETICS