Bersaldegenin-1,3,5-orthoacetate induces caspase-independent cell death, DNA damage and cell cycle arrest in human cervical cancer HeLa cells

Identification of Flavonoids and Bufadienolides and Cytotoxic Effects of Kalanchoe daigremontiana Extracts on Human Cancer Cell Lines

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Bufadienolides from the whole plants of Helleborus foetidus and their cytotoxicity

(2020) Tomoki Iguchi et al.   PHYTOCHEMISTRY

Alpha-Hederin, the Active Saponin of Nigella sativa, as an Anticancer Agent Inducing Apoptosis in the SKOV-3 Cell Line

(2019) Anna Adamska et al.   MOLECULES

Multiple cytotoxic effects of gamabufotalin against human glioblastoma cell line U-87

(2019) Bo Yuan et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Proscillaridin A exerts anti-tumor effects through GSK3β activation and alteration of microtubule dynamics in glioblastoma

(2018) Raphael Berges et al.   Cell Death & Disease

Arenobufagin induces MCF-7 cell apoptosis by promoting JNK-mediated multisite phosphorylation of Yes-associated protein

(2018) Li-Juan Deng et al.   Cancer Cell International

Anti-proliferative and pro-apoptotic effects of cinobufagin on human breast cancer MCF-7 cells and its molecular mechanism

(2017) Ling Zhu et al.   NATURAL PRODUCT RESEARCH

Bufadienolides of Kalanchoe species: an overview of chemical structure, biological activity and prospects for pharmacological use

(2017) Joanna Kolodziejczyk-Czepas et al.   PHYTOCHEMISTRY REVIEWS

Metabolites profiling of 10 bufadienolides in human liver microsomes and their cytotoxicity variation in HepG2 cell

(2016) Lingyu Han et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Bufalin induces apoptosis in vitro and has Antitumor activity against human lung cancer xenografts in vivo

(2016) Shin-Hwar Wu et al.   ENVIRONMENTAL TOXICOLOGY

New Bufadienolides Isolated from the Roots of Kalanchoe daigremontiana (Crassulaceae)

(2016) Barbara Moniuszko-Szajwaj et al.   MOLECULES

Antioxidant efficacy of Kalanchoe daigremontiana bufadienolide-rich fraction in blood plasma in vitro

(2016) Joanna Kolodziejczyk-Czepas et al.   PHARMACEUTICAL BIOLOGY

Cinobufagin inhibits tumor growth by inducing intrinsic apoptosis through AKT signaling pathway in human nonsmall cell lung cancer cells

(2016) Guangxin Zhang et al.   Oncotarget

Cinobufagin exerts anti-proliferative and pro-apoptotic effects through the modulation ROS-mediated MAPKs signaling pathway

(2015) Seung Ho Baek et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Cardenolides and Bufadienolide Glycosides from Kalanchoe tubiflora and Evaluation of Cytotoxicity

(2013) Hui-Chi Huang et al.   PLANTA MEDICA

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Bufadienolides and their antitumor activity

(2011) Huimin Gao et al.   NATURAL PRODUCT REPORTS

Bufogargarizins A and B: Two Novel 19-Norbufadienolides with Unprecedented Skeletons from the Venom of Bufo bufo gargarizans

(2010) Hai-Yan Tian et al.   CHEMISTRY-A EUROPEAN JOURNAL

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Natural and synthetic 2H-pyran-2-ones and their versatility in organic synthesis

(2009) Atul Goel et al.   TETRAHEDRON