Ellagic Acid Protects Dopamine Neurons via Inhibition of NLRP3 Inflammasome Activation in Microglia

Kir6.1/K-ATP channel on astrocytes protects against dopaminergic neurodegeneration in the MPTP mouse model of Parkinson’s disease via promoting mitophagy

(2019) Zhao-Li Hu et al.   BRAIN BEHAVIOR AND IMMUNITY

Naringenin Produces Neuroprotection Against LPS-Induced Dopamine Neurotoxicity via the Inhibition of Microglial NLRP3 Inflammasome Activation

(2019) Ce Chen et al.   Frontiers in Immunology

Renoprotective effects of artemisinin and hydroxychloroquine combination therapy on IgA nephropathy via suppressing NF-κB signaling and NLRP3 inflammasome activation by exosomes in rats

(2019) Lixia Bai et al.   BIOCHEMICAL PHARMACOLOGY

MPTP-driven NLRP3 inflammasome activation in microglia plays a central role in dopaminergic neurodegeneration

(2018) Eunju Lee et al.   CELL DEATH AND DIFFERENTIATION

Icariin Reduces Dopaminergic Neuronal Loss and Microglia-Mediated Inflammation in Vivo and in Vitro

(2018) Guo-Qing Wang et al.   Frontiers in Molecular Neuroscience

Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice

(2018) Richard Gordon et al.   Science Translational Medicine

Astrocytic Orosomucoid-2 Modulates Microglial Activation and Neuroinflammation

(2017) Myungjin Jo et al.   JOURNAL OF NEUROSCIENCE

Aging and Parkinson's disease: Different sides of the same coin?

(2017) Timothy J. Collier et al.   MOVEMENT DISORDERS

Hydroxysafflor Yellow A Improves Motor Dysfunction in the Rotenone-Induced Mice Model of Parkinson’s Disease

(2017) Tian Wang et al.   NEUROCHEMICAL RESEARCH

Quantitative Analysis and In vitro Anti-inflammatory effects of gallic acid, ellagic acid, and quercetin from radix sanguisorbae

(2016) Hyeun-Kyoo Shin et al.   Pharmacognosy Magazine

Mechanism and Regulation of NLRP3 Inflammasome Activation

(2016) Yuan He et al.   TRENDS IN BIOCHEMICAL SCIENCES

Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome

(2015) Yiqing Yan et al.   CELL

Lipoic Acid: Its Antioxidant and Anti-Inflammatory Role and Clinical Applications

(2015) Fabiana Moura et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

TDP-43 activates microglia through NF-κB and NLRP3 inflammasome

(2015) Weihua Zhao et al.   EXPERIMENTAL NEUROLOGY

Ellagic acid prevents monocrotaline-induced pulmonary artery hypertension via inhibiting NLRP3 inflammasome activation in rats

(2015) Bing Tang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

The pathogenic role of the inflammasome in neurodegenerative diseases

(2015) Leslie C. Freeman et al.   JOURNAL OF NEUROCHEMISTRY

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin

(2012) Wei Shao et al.   NATURE

Sensing and reacting to microbes through the inflammasomes

(2012) Luigi Franchi et al.   NATURE IMMUNOLOGY

Dopaminergic neurotoxicant 6-OHDA induces oxidative damage through proteolytic activation of PKCδ in cell culture and animal models of Parkinson's disease

(2011) Calivarathan Latchoumycandane et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Anti-inflammatory activities of resveratrol in the brain: Role of resveratrol in microglial activation

(2010) Feng Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Neuroinflammation is a key player in Parkinson’s disease and a prime target for therapy

(2010) Li Qian et al.   JOURNAL OF NEURAL TRANSMISSION

Resveratrol Protects Dopamine Neurons Against Lipopolysaccharide-Induced Neurotoxicity through Its Anti-Inflammatory Actions

(2010) F. Zhang et al.   MOLECULAR PHARMACOLOGY

Parkinson's disease

(2009) Andrew J Lees et al.   LANCET

Amperometric measurements of catecholamine release from single vesicles in MN9D cells

(2008) Yan Dong et al.   JOURNAL OF NEUROCHEMISTRY