Exome sequencing identifies ARID2 as a novel tumor suppressor in early-onset sporadic rectal cancer

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SWI/SNF-compromised cancers are susceptible to bromodomain inhibitors

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Dangerous liaisons: interplay between SWI/SNF, NuRD, and Polycomb in chromatin regulation and cancer

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The GenomeAsia 100K Project enables genetic discoveries across Asia

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Universal Patterns of Selection in Cancer and Somatic Tissues

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XPNPEP3 is a novel transcriptional target of canonical Wnt/β-catenin signaling

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A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing

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Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations

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Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

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Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability

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The chromatin-remodeling subunit Baf200 promotes homology-directed DNA repair and regulates distinct chromatin-remodeling complexes

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Ca2+/nuclear factor of activated T cells signaling is enriched in early-onset rectal tumors devoid of canonical Wnt activation

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Global patterns and trends in colorectal cancer incidence and mortality

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A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC

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Chromatin remodeling gene ARID2 targets cyclin D1 and cyclin E1 to suppress hepatoma cell progression

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Exome sequencing reveals frequent inactivating mutations inARID1A, ARID1B, ARID2andARID4Ain microsatellite unstable colorectal cancer

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Rectal cancer profiling identifies distinct subtypes in India based on age at onset, genetic, epigenetic and clinicopathological characteristics

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ARID1B, a member of the human SWI/SNF chromatin remodeling complex, exhibits tumour-suppressor activities in pancreatic cancer cell lines

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Mutational heterogeneity in cancer and the search for new cancer-associated genes

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Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

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Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy

(2013) Cigall Kadoch et al.   NATURE GENETICS

Mutational landscape of gingivo-buccal oral squamous cell carcinoma reveals new recurrently-mutated genes and molecular subgroups

(2013)   Nature Communications

A Landscape of Driver Mutations in Melanoma

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A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

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Recurrent inactivating mutations ofARID2in non-small cell lung carcinoma

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Evidence for possible non-canonical pathway(s) driven early-onset colorectal cancer in India

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Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

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TCF12 Protein Functions as Transcriptional Repressor of E-cadherin, and Its Overexpression Is Correlated with Metastasis of Colorectal Cancer

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Essential Role of ARID2 Protein-containing SWI/SNF Complex in Tissue-specific Gene Expression

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Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma

(2011) Meng Li et al.   NATURE GENETICS

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

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Clinical Relevance of Microsatellite Instability in Colorectal Cancer

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Fast and accurate short read alignment with Burrows-Wheeler transform

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Frequency and type of KRAS mutations in routine diagnostic analysis of metastatic colorectal cancer

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KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradiotherapy

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